Black Haw Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Black Haw interacts with medications. The heart of this page is the interaction list — every drug Black Haw is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Black Haw is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Black Haw against your medication
Add one medicationDrugs that interact with Black Haw
0 medications have a known interaction with Black Haw, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Black Haw. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Black Haw combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Black Haw: Uses, Safety & Side Effects
Black Haw is a traditional herbal bark long used to ease menstrual cramps and uterine spasms, but modern human studies are very limited. It contains compounds that may relax smooth muscle, but its effectiveness is not well proven, and it should be used with caution, especially during pregnancy. Talk to a pharmacist or doctor before trying it.

- Scientific name
- Viburnum prunifolium
- Family
- Adoxaceae
- Part used
- Bark of the stem and root
- Common forms
- Tea (decoction), tincture, liquid extract, capsules, dried bark
- Menstrual cramps
- Uterine spasms
- Threatened miscarriage (traditional)
- Menopause-related discomfort
- General muscle cramps
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Generally used in traditional medicine, but human safety data are limited.
When used orally. Some evidence suggests black haw has uterine relaxant effects; avoid using.
Read the full pregnancy detailInsufficient reliable information available.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Black Haw (Viburnum prunifolium) is a deciduous shrub or small tree native to the southeastern and central United States. It is also known as Nanny Bush, Stag Bush, and Southern Black Haw.
The part used in herbal medicine is the bark, taken from the stem or root. It has a long history of folk use, especially among Native American and early American practitioners, mainly for women's health concerns.
Today it is sold as a tea, tincture, liquid extract, or capsule. Most of its reputation comes from tradition rather than modern clinical testing.
How it works
Black Haw bark contains several plant compounds, including scopoletin (a coumarin), salicin-like substances, tannins, and other constituents. Researchers have suggested that some of these may help relax smooth muscle, such as the muscle of the uterus, which could in theory ease cramping.
It is sometimes described as a "uterine relaxant" or antispasmodic. However, these ideas are based largely on laboratory and animal studies, not on strong human trials, so the real-world effect in people is uncertain.
Does Black Haw work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
For Black Haw, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.
Also studied for 4 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Asthma
Although there has been interest in using oral black haw for asthma, there is insufficient reliable information about the clinical effects of black haw for this purpose.
Insufficient Reliable Evidence To Rate Diarrhea
Although there has been interest in using oral black haw for diarrhea, there is insufficient reliable information about the clinical effects of black haw for this purpose.
Insufficient Reliable Evidence To Rate Dysmenorrhea
Although there has been interest in using oral black haw for dysmenorrhea, there is insufficient reliable information about the clinical effects of black haw for this purpose.
Insufficient Reliable Evidence To Rate Miscarriage
Although there has been interest in using oral black haw for miscarriage, there is insufficient reliable information about the clinical effects of black haw for this purpose.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
Black Haw has been used traditionally without widespread reports of serious harm, but modern safety data are limited. This means we cannot be sure how safe it is, especially with long-term use or high doses.
It contains salicylate-related and tannin compounds. People who are sensitive to aspirin or salicylates, or who have a history of kidney stones, should be cautious and check with a clinician first.
Pregnancy: Even though it has been used traditionally in pregnancy, its effects on the uterus are not well understood. Because of this uncertainty, it is best to avoid Black Haw during pregnancy unless a doctor specifically recommends it. Breastfeeding: There is not enough information to know if it is safe, so nursing mothers should also avoid it. Always talk to a pharmacist or doctor before use.
Side effects
Reported side effects are not well documented because formal studies are scarce. Possible issues, based on its plant chemistry, include stomach upset or nausea, and the bitter, astringent tannins may cause digestive irritation in some people.
Because Black Haw contains salicylate-like compounds, people who react to aspirin could in theory have an allergic or sensitivity reaction. Stop using it and seek care if you notice rash, swelling, trouble breathing, or other signs of an allergic reaction.
Dosing
There is no established standardized dose for Black Haw. Traditional preparations include teas (decoctions of the bark), tinctures, and liquid extracts, but reliable dosing has not been confirmed by modern research.
If you choose to use a product, follow the directions on the label and do not exceed the recommended amount. Because strength varies between products, it is wise to check with a pharmacist or doctor first, especially if you take other medicines or have a health condition.
Black Haw & Pregnancy
Black Haw & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 1 references that drive our Black Haw monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Brands that make products with Black Haw
6 brands in our database make a supplement containing Black Haw.
Supplement products with Black Haw
20 products in our database contain Black Haw. Open any to see its full ingredient list and every drug interaction we check.
Black Haw: Common Questions
What is Black Haw used for, and does it work?
Does Black Haw interact with prescription medications?
How are Black Haw interactions rated?
Is it safe to take Black Haw with my medications?
Where does this Black Haw interaction information come from?
What is Black Haw used for?
Is Black Haw safe to take?
Can I take Black Haw if I am pregnant or breastfeeding?
How is Black Haw usually taken?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Black Haw
A rotating sample of real supplements in our database that list Black Haw — open any to see its full ingredients and every drug interaction we check.
- Black Haw Bark Vanilla Flavor by TerraVita
- Cramp Care by Herb Pharm
- Black Haw Bark Chocolate Flavor by TerraVita
- Black Haw Alcohol Free by Herbal Terra
- Black Haw by Hawaii Pharm
- Black Haw Bark Powder by TerraVita Premium Collection
- Black Haw by Herbal Terra
- Black Haw Bark Mint Flavor by TerraVita
- Black Haw by Hawaii Pharm
- Black Haw Bark by TerraVita
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