Burdock Interactions Overview
Check For Interactions With Burdock
Burdock
- Arctium lappa
- Arctium
- Bardana
- Bardana-minor
- Bardanae Radix
- Bardane
- Beggar's Buttons
- Burdock Root Extract
- Burr Seed
- Cocklebur
- Cockle Buttons
- Fox's Clote
- Gobo
- Glouteron
- Grande Bardane
- Great Bur
- Great Burdocks
- Hardock
- Harebur
- Lappa
- Love Leaves
- Niubang
- Niu Ba

Additional Details
Is Burdock Safe? Are There Any Warnings?
Burdock root is generally considered safe when consumed as a food in common amounts. Topical use of an emulsion containing burdock fruit extract has been deemed safe for short-term application to the face. However, there is insufficient reliable information available about the safety of using burdock in supplemental doses. Pregnant and breastfeeding individuals should avoid using burdock due to a lack of reliable information on its safety during these periods.
Adverse Effects
Burdock is well-tolerated when used as a food, and historical use suggests few adverse effects. However, allergic reactions like contact dermatitis and anaphylaxis have been reported, albeit rarely.
Effectiveness
While there is interest in using burdock for various purposes, such as acne treatment, aging skin, atopic dermatitis, breast cancer, common cold symptoms, diabetes, diverticulitis, dry skin, gout, hepatitis, metabolic syndrome, urinary tract infections, and vaginitis, the reliable evidence supporting its effectiveness is insufficient for most of these uses. Some preliminary research exists, but more robust studies are needed to establish its benefits.
Dosing & Administration
Research on burdock dosing is limited, and typical dosing is unavailable for both adults and children.
Standardization & Formulation
Information on the standardization of burdock fruit is limited. Some clinical research utilized a product containing 1.2% burdock fruit extract standardized to 0.25% arctiin.
Interaction Overview
Burdock might interact with anticoagulant/antiplatelet drugs and herbs/supplements, potentially increasing the risk of bleeding. Cross-allergenicity and perioperative interactions are also noted.
Pharmacokinetics
Burdock constituents are absorbed and metabolized in the body. The constituent arctiin gets converted into arctigenin, with excretion occurring primarily through urine and feces.
Mechanism of Action
Burdock acts through various mechanisms, including anticancer, anti-inflammatory, antioxidant, antimicrobial, antiplatelet, hormonal, immunologic, metabolic, and respiratory effects. Its bioactive components include arctigenin, arctiin, beta-eudesmol, caffeic acid, chlorogenic acid, diarctigenin, inulin, lappaol, tannin, trachelogenin, and sitosterol-beta-D-glucopyranoside. Burdock is also a source of vitamins, minerals, and amino acids.
Drugs that interact with Burdock
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLCs