Iodine Interactions Overview
Check For Interactions With Iodine
Iodine
- KI
- Lugol's Solution

Additional Details
Is Iodine Safe? Are They Any Warnings?
Iodine is a trace element necessary for the production of thyroid hormone. It is generally safe to use orally and topically in appropriate amounts. Oral iodine should not exceed the recommended daily intake level to avoid side effects like thyroid dysfunction and other complications. However, in some regions like Japan, higher dietary intake of iodine has been observed without adverse effects. It is also safe to use during pregnancy and lactation, but excessive intake may lead to increased iodine levels in breast milk and potential risks for the baby's development.
How Is Iodine Thought To Work?
Iodine is needed for the production of thyroid hormone, which plays a crucial role in regulating metabolism. It helps maintain the normal function of the thyroid gland and prevents iodine deficiency. The addition of iodine to salt has been effective in reducing deficiency in the US and Canada. Dietary sources of iodine include iodized salt, seaweed, marine products, eggs, and cow's milk.
Pharmacokinetics
Iodine exists in various forms and is commonly used as potassium or sodium salts. It can be taken orally as iodized salt or applied topically in the form of solutions or ointments containing povidone-iodine. The pharmacokinetics of iodine are not extensively studied.
Interaction Overview (See Below For Full List)
Iodine may interact with certain medications and conditions. Caution should be exercised when combining iodine with medications like amiodarone and antithyroid drugs, as it may cause adverse effects or alter their effectiveness. Individuals with dermatitis herpetiformis or thyroid disease should be cautious when using iodine. There are no known interactions with supplements or lab tests.
Common Side Effects To Watch For
When used in appropriate amounts, iodine is generally well-tolerated. However, some common side effects to watch for include abdominal upset, diarrhea, goiter, headache, metallic taste, nausea, and skin irritation. Serious adverse effects are rare but may include hypersensitivity reactions such as anaphylaxis and angioedema.
Drugs that interact with Iodine
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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