Herb & supplement monograph

Mentabolan Drug Interactions, Uses, Effectiveness, Safety & More

Medically reviewed by ·Updated June 2026
What is this page for?

First and foremost: how Mentabolan interacts with medications. The heart of this page is the interaction list — every drug Mentabolan is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Mentabolan is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

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Interaction report

Drugs that interact with Mentabolan

0 medications have a known interaction with Mentabolan, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Mentabolan. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Mentabolan combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Mentabolan: Uses, Safety & Side Effects

Medically reviewed by · Reviewed June 2026 ·
The bottom line

Mentabolan is a marketing name for a synthetic steroid-like compound (often linked to dimethandrostenediol/prohormone chemicals) sold in some bodybuilding 'prohormone' products, not a natural herb. These designer steroid products can be unsafe, may be illegal or unapproved, and have been associated with liver and hormonal harm, so we strongly recommend avoiding them and talking with a doctor or pharmacist.

Part used
Not applicable (synthetic compound)
Common forms
Capsules, tablets
People commonly use it for
  • Muscle building and strength
  • Athletic performance enhancement
  • Body recomposition
  • Sold as a 'prohormone' bodybuilding supplement

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallBest avoided

It is a synthetic steroid-type compound with real risks and little reliable safety data.

PregnancyPossibly Unsafe

When used orally. Prohormones can be converted to active hormones in the body and cause adverse effects such as menstrual irregularities, infertility,...

Read the full pregnancy detail
BreastfeedingPossibly Unsafe

When used orally. Prohormones can be converted to active hormones in the body and cause adverse effects such as menstrual irregularities, infertility,...

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Mentabolan is not an herb or a plant. It is a brand or marketing name used for a synthetic, steroid-like chemical sold in some 'prohormone' or 'anabolic' bodybuilding supplements. Products with this name have been associated with compounds related to designer anabolic steroids, sometimes described by chemical names like dimethandrostenediol.

These products are usually sold online or in supplement shops and are marketed to people who want to build muscle, gain strength, or change their body shape quickly. Despite being sold as 'supplements,' compounds like this act more like drugs than like food or vitamins.

It is important to know that ingredients in these products are often poorly labeled, change over time, and may not match what is on the bottle. Many such designer steroid products have been the target of warnings and recalls by health authorities.

How it works

Mentabolan-type compounds are thought to act like anabolic steroids or steroid precursors (prohormones). The idea is that the body converts the compound, or that it directly stimulates androgen (male hormone) receptors, which can promote muscle growth.

Because it may behave like a hormone, it can also disrupt the body's natural hormone balance. This is the same mechanism behind many of its side effects, such as suppressing the body's own testosterone production.

Most of what is 'known' about these mechanisms comes from comparisons to other anabolic steroids rather than from direct, careful study of this specific product.

Effectiveness

Does Mentabolan work?

Here’s what the research actually shows for each use — graded by Natural Medicines and reviewed by .

Evidence overview · 4 uses evaluated
4 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Mentabolan, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 4 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Athletic performance
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using mentabolan for athletic performance, there is insufficient reliable information about the clinical effects of mentabolan for this purpose.

Insufficient Reliable Evidence To Rate Exercise-induced muscle damage
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using mentabolan for muscle recovery after exercise, there is insufficient reliable information about the clinical effects of mentabolan for this purpose.

Insufficient Reliable Evidence To Rate Muscle strength
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using mentabolan to increase muscle strength, there is insufficient reliable information about the clinical effects of mentabolan for this purpose.

Insufficient Reliable Evidence To Rate Obesity
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using mentabolan for weight loss, there is insufficient reliable information about the clinical effects of mentabolan for this purpose.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

We recommend avoiding Mentabolan. Designer steroid and prohormone products have been linked to serious problems, including liver damage, hormonal imbalance, and heart and blood pressure issues. Some have been pulled from the market by regulators.

People with liver disease, heart disease, high blood pressure, hormone-sensitive conditions, or a history of mood disorders are at especially high risk. These products should never be used by teenagers or young adults whose bodies are still developing.

Pregnancy and breastfeeding: Avoid completely. Hormone-altering steroid compounds can harm a developing baby and may pass into breast milk. There is no safe known use during these times.

Athletes should also note that these substances are typically banned in tested sports and can cause a failed drug test.

Side effects

Reported and expected side effects of anabolic/prohormone products like this include:

  • Liver injury, sometimes serious, including jaundice (yellow skin or eyes)
  • Suppressed natural testosterone and other hormone changes
  • Acne, oily skin, and hair loss
  • Mood changes, irritability, or aggression
  • High blood pressure and unhealthy cholesterol changes
  • In some people, breast tissue growth (men) or menstrual and voice changes (women)

Rare but serious harms can include heart problems and significant liver toxicity. Any yellowing of the skin or eyes, dark urine, severe abdominal pain, or chest pain needs urgent medical care.

Dosing

There is no established, safe, or medically recommended dose for Mentabolan. It is not an approved medication or a tested supplement, and product labels may be inaccurate.

Because of the serious safety concerns, we do not recommend using it at any dose. If you are considering it or already taking it, please speak with a doctor or pharmacist before continuing.

Pregnancy & Breastfeeding

Mentabolan & Pregnancy

Possibly Unsafe

When used orally. Prohormones can be converted to active hormones in the body and cause adverse effects such as menstrual irregularities, infertility, hair loss, and acne. Prohormones have also been associated with hepatotoxicity and increased risk of cardiovascular disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing prohormones are dangerous. Avoid using.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100.

Mentabolan & Breastfeeding

Possibly Unsafe

When used orally. Prohormones can be converted to active hormones in the body and cause adverse effects such as menstrual irregularities, infertility, hair loss, and acne. Prohormones have also been associated with hepatotoxicity and increased risk of cardiovascular disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing prohormones are dangerous. Avoid using.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 1 references that drive our Mentabolan monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Mentabolan

1 brand in our database make a supplement containing Mentabolan.

Product directory

Supplement products with Mentabolan

1 product in our database contain Mentabolan. Open any to see its full ingredient list and every drug interaction we check.

Pharmacist Counseling Corner

Mentabolan: Common Questions

What is Mentabolan used for, and does it work?
People use Mentabolan for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Mentabolan interact with prescription medications?
We do not currently list any known drug interactions for Mentabolan. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Mentabolan interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Mentabolan with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Mentabolan interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
Is Mentabolan a natural herb?
No. Despite being sold as a 'supplement,' it is a synthetic, steroid-like compound (a prohormone), not a plant or herbal product.
Is Mentabolan safe to take?
We do not consider it safe. Designer steroid products like this have been linked to liver damage, hormone disruption, and heart problems, and they lack proper safety testing.
Will Mentabolan help me build muscle?
It is marketed for muscle and strength gains, but there is no reliable human research proving it works safely, and the risks are significant.
Can I take Mentabolan if I'm pregnant or breastfeeding?
No. Hormone-altering steroid compounds should be completely avoided during pregnancy and breastfeeding because they can harm the baby.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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