Herb & supplement monograph

Pantothenic Acid Drug Interactions, Uses, Effectiveness, Safety & More

Medically reviewed by ·Updated July 2026
What is this page for?

First and foremost: how Pantothenic Acid interacts with medications. The heart of this page is the interaction list — every drug Pantothenic Acid is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Pantothenic Acid is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

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Interaction report

Drugs that interact with Pantothenic Acid

0 medications have a known interaction with Pantothenic Acid, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Pantothenic Acid. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Pantothenic Acid combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Pantothenic Acid: Uses, Safety & Side Effects

Medically reviewed by · Reviewed July 2026 ·
The bottom line

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nearly all foods, and most people meet their needs through diet. Supplements are generally considered safe, but evidence that extra amounts treat acne, high cholesterol, or other conditions is limited.

Common forms
Tablets, capsules, softgels, multivitamins, topical creams (as panthenol)
People commonly use it for
  • General nutrition and energy
  • Skin and hair health
  • Acne (topical and oral)
  • Wound healing (as panthenol)
  • Cholesterol support (as pantethine)

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallLikely safe

Considered safe for most people at typical supplement doses, with few side effects.

PregnancyLikely Safe

When used orally and appropriately. The daily adequate intake (AI) during pregnancy is 6 mg.

Read the full pregnancy detail
BreastfeedingLikely Safe

When used orally and appropriately. The daily adequate intake (AI) during lactation is 7 mg.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

Pantothenic acid is one of the B vitamins, known as vitamin B5. It is a water-soluble vitamin, which means your body does not store large amounts of it and you need a steady supply from food.

The name comes from a Greek word meaning "from everywhere," because this vitamin is found in almost all plant and animal foods. Good sources include meat, eggs, whole grains, legumes, avocados, mushrooms, and many vegetables.

People take pantothenic acid as part of a multivitamin or B-complex, or as a separate supplement. A related form called panthenol is used in many skin and hair products, and a form called pantethine has been studied for cholesterol.

How it works

Pantothenic acid is needed to make a molecule called coenzyme A, which your body uses to break down fats, carbohydrates, and proteins for energy. It also helps build certain fats, hormones, and other important substances.

Because coenzyme A is involved in so many basic chemical reactions, the vitamin plays a role throughout the body. This broad role is why marketers connect it to energy, skin, and hair, but having more than your body needs does not necessarily speed these processes up.

The proposed effects on acne and cholesterol come mostly from small studies and laboratory work, and the exact mechanisms are not fully proven in humans.

Effectiveness

Does Pantothenic Acid work?

Here’s what the research actually shows for each use — graded by Natural Medicines and reviewed by .

Evidence overview · 44 uses evaluated
1 Effective 1 Leans ineffective 42 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.
Effective Pantothenic acid deficiency
Rating & evidence shown verbatim from Natural Medicines

Taking pantothenic acid 5-10 mg daily is effective for treating and preventing pantothenic acid deficiency.

Sources Ref 15
Possibly Ineffective Radiation dermatitis
Rating & evidence shown verbatim from Natural Medicines

Topical dexpanthenol does not seem to be beneficial for preventing or treating radiation dermatitis.

Also studied for 42 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Acne
Rating & evidence shown verbatim from Natural Medicines

Oral or topical pantothenic acid has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

Insufficient Reliable Evidence To Rate Alcoholism
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for improving recovery from alcoholism, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Allergic rhinitis (hay fever)
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for allergic rhinitis, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Alopecia areata
Rating & evidence shown verbatim from Natural Medicines

Pantothenic acid has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

Insufficient Reliable Evidence To Rate Anxiety
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for anxiety, there is insufficient reliable information about the clinical effects of pantothenic acid for this purpose.

Insufficient Reliable Evidence To Rate Asthma
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for asthma, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Athletic performance
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid to improve athletic performance, there is insufficient reliable information about the clinical effects of pantothenic acid for this purpose.

Insufficient Reliable Evidence To Rate Atopic dermatitis (eczema)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if topical pantothenic acid is beneficial in infants or children with atopic dermatitis.

Insufficient Reliable Evidence To Rate Attention deficit-hyperactivity disorder (ADHD)
Rating & evidence shown verbatim from Natural Medicines

Oral pantothenic acid has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

Insufficient Reliable Evidence To Rate Autism spectrum disorder
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for autism spectrum disorder, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Carpal tunnel syndrome
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for carpal tunnel syndrome, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Cheilitis
Rating & evidence shown verbatim from Natural Medicines

Topical pantothenic acid has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

Insufficient Reliable Evidence To Rate Chronic fatigue syndrome (CFS)
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for CFS, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Conjunctivitis
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral or ocular pantothenic acid for conjunctivitis, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Constipation
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral or intramuscular dexpanthenol is beneficial for constipation.

Insufficient Reliable Evidence To Rate Dandruff
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral or topical pantothenic acid for dandruff, is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Depression
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for depression, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Diaper rash
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using topical pantothenic acid for diaper rash, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Dry eye
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using ocular pantothenic acid for dry eye, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Dry skin
Rating & evidence shown verbatim from Natural Medicines

It is unclear if topical dexpanthenol is beneficial for patients with dry skin.

Insufficient Reliable Evidence To Rate Epilepsy
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for epilepsy, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Eye trauma
Rating & evidence shown verbatim from Natural Medicines

It is unclear if ocular dexpanthenol is beneficial for eye trauma.

Insufficient Reliable Evidence To Rate Heart failure
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for heart failure, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Herpes zoster (shingles)
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral or topical pantothenic acid for shingles, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Insomnia
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for insomnia, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Laser skin resurfacing
Rating & evidence shown verbatim from Natural Medicines

It is unclear if topical dexpanthenol or pantothenic acid can reduce adverse effects after laser skin resurfacing procedures.

Insufficient Reliable Evidence To Rate Multiple sclerosis (MS)
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for MS, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Muscular dystrophy
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for muscular dystrophy, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Nipple fissures
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using topical pantothenic acid for nipple fissures, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Obesity
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for obesity, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Parkinson disease
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for Parkinson disease, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Poison oak and poison ivy dermatitis
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using topical pantothenic acid for poison ivy dermatitis, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Postoperative pain
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral pantothenic acid is beneficial for postoperative pain.

Insufficient Reliable Evidence To Rate Postoperative sore throat
Rating & evidence shown verbatim from Natural Medicines

It is unclear if pantothenic acid lozenges are beneficial for postoperative sore throat.

Insufficient Reliable Evidence To Rate Pregnancy-related leg cramps
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for pregnancy-related leg cramps, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Premenstrual syndrome (PMS)
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for PMS, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Respiratory tract infections
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for respiratory tract infections, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Rhinosinusitis
Rating & evidence shown verbatim from Natural Medicines

It is unclear if nasal dexpanthenol is beneficial for rhinosinusitis.

Insufficient Reliable Evidence To Rate Skin irritation
Rating & evidence shown verbatim from Natural Medicines

It is unclear if topical dexpanthenol is beneficial for preventing or treating skin irritation due to sodium lauryl sulfate.

Insufficient Reliable Evidence To Rate Ulcerative colitis
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral or rectal pantothenic acid for ulcerative colitis, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Vertigo
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral pantothenic acid for vertigo, there is insufficient reliable information about the clinical effects of pantothenic acid for this condition.

Insufficient Reliable Evidence To Rate Wound healing
Rating & evidence shown verbatim from Natural Medicines

Preliminary clinical research suggests that oral dexpanthenol might be beneficial for wound healing.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

Pantothenic acid is generally considered safe for most people when taken at normal amounts. Because it is water-soluble, extra amounts are usually passed in the urine rather than stored.

People with kidney problems or other chronic health conditions should talk with a pharmacist or doctor before taking high-dose supplements. If you have a medical condition or take medications, it is always wise to check first.

For pregnancy and breastfeeding, the amounts found in food and standard prenatal vitamins are appropriate and expected. There is not enough safety information on very high-dose supplements, so avoid those unless your doctor recommends them.

Side effects

At usual doses, pantothenic acid rarely causes side effects. Very high doses (much larger than dietary amounts) have occasionally been linked to diarrhea or mild digestive upset.

Serious reactions are uncommon. As with any supplement, an allergic reaction is possible. Stop use and seek medical care if you develop rash, swelling, or trouble breathing.

Pantothenic Acid: Reported Adverse Effects

Documented safety reports on Pantothenic Acid from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Orally, pantothenic acid is generally well tolerated. Topically and intramuscularly, dexpanthenol, a synthetic form of pantothenic acid, seems to be well tolerated.

Most Common Adverse Effects:

Topically: Burning, contact dermatitis, eczema, irritation, and itching related to dexpanthenol.

Reports by condition
Dermatitis Dermatologic

Topically, dexpanthenol has been associated with itching, burning, skin irritation, contact dermatitis, and eczema. Three cases of allergic contact dermatitis have been reported.

  1. Schmuth, M., Wimmer, M. A., Hofer, S., Sztankay, A., Weinlich, G., Linder, D. M., Elias, P. M., Fritsch, P. O., and Fritsch, E. Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Br.J.Dermatol. 2
  2. Schreck, U., Paulsen, F., Bamberg, M., and Budach, W. Intraindividual comparison of two different skin care conceptions in patients undergoing radiotherapy of the head-and-neck region. Creme or powder? Strahlenther.Onkol. 2002;178(6):321-329.
  3. Herbst, R. A., Uter, W., Pirker, C., Geier, J., and Frosch, P. J. Allergic and non-allergic periorbital dermatitis: patch test results of the Information Network of the Departments of Dermatology during a 5-year period. Contact Dermatitis 2004;51(1):13-1
  4. Scott LN, Fiume M, Bergfeld WF, et al. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol 2022;41(3_suppl):77-128.
  5. Peltier E, Trapp S, de Salvo R, et al. A new dexpanthenol-containing liquid cleanser for atopic-prone skin: Results from two prospective clinical studies evaluating cutaneous tolerability, moisturization potential, and effects on barrier function. J Cosme
  6. Han J, Warshaw EM. Allergic Contact Dermatitis to Panthenol in "Hypoallergenic" Products. Dermatitis 2023;34(1):62-63.
  7. Blanchard G, Kerre S, Walker A, et al. Allergic contact dermatitis from pantolactone and dexpanthenol in wound healing creams. Contact Dermatitis 2022;87(5):468-471.
Diarrhea Gastrointestinal

Orally, pantothenic acid has been associated with diarrhea.

  1. Champault, G. and Patel, J. C. [Treatment of constipation with Bepanthene]. Med.Chir Dig. 1977;6(1):57-59.
  2. Scott LN, Fiume M, Bergfeld WF, et al. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol 2022;41(3_suppl):77-128.
Myasthenia gravis Cardiovascular

There is one case of eosinophilic pleuropericardial effusion in a patient taking pantothenic acid 300 mg per day in combination with biotin 10 mg per day for 2 months.

  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no single standardized "treatment" dose of pantothenic acid for most uses. Nutrition authorities set general daily intake amounts for adults to prevent deficiency, and most people easily get this from food.

Supplement products vary widely in how much they contain, with some marketed for acne or other uses providing amounts far above dietary needs. The safety and value of these high doses are not well established.

The best approach is to follow the directions on the product label and check with your pharmacist or doctor, especially before taking high-dose products. Do not assume more is better.

Pregnancy & Breastfeeding

Pantothenic Acid & Pregnancy

Likely Safe

When used orally and appropriately. The daily adequate intake (AI) during pregnancy is 6 mg.

  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706.

Pantothenic Acid & Breastfeeding

Likely Safe

When used orally and appropriately. The daily adequate intake (AI) during lactation is 7 mg.

  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 11 references that drive our Pantothenic Acid monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  4. Schmuth, M., Wimmer, M. A., Hofer, S., Sztankay, A., Weinlich, G., Linder, D. M., Elias, P. M., Fritsch, P. O., and Fritsch, E. Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Br.J.Dermatol. 2 PubMed
  5. Schreck, U., Paulsen, F., Bamberg, M., and Budach, W. Intraindividual comparison of two different skin care conceptions in patients undergoing radiotherapy of the head-and-neck region. Creme or powder? Strahlenther.Onkol. 2002;178(6):321-329. PubMed
  6. Herbst, R. A., Uter, W., Pirker, C., Geier, J., and Frosch, P. J. Allergic and non-allergic periorbital dermatitis: patch test results of the Information Network of the Departments of Dermatology during a 5-year period. Contact Dermatitis 2004;51(1):13-1 PubMed
  7. Champault, G. and Patel, J. C. [Treatment of constipation with Bepanthene]. Med.Chir Dig. 1977;6(1):57-59.
  8. Scott LN, Fiume M, Bergfeld WF, et al. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol 2022;41(3_suppl):77-128. PubMed
  9. Han J, Warshaw EM. Allergic Contact Dermatitis to Panthenol in "Hypoallergenic" Products. Dermatitis 2023;34(1):62-63. PubMed
  10. Blanchard G, Kerre S, Walker A, et al. Allergic contact dermatitis from pantolactone and dexpanthenol in wound healing creams. Contact Dermatitis 2022;87(5):468-471. PubMed
  11. Peltier E, Trapp S, de Salvo R, et al. A new dexpanthenol-containing liquid cleanser for atopic-prone skin: Results from two prospective clinical studies evaluating cutaneous tolerability, moisturization potential, and effects on barrier function. J Cosme PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Pantothenic Acid

1,492 brands in our database make a supplement containing Pantothenic Acid.

Product directory

Supplement products with Pantothenic Acid

17,082 products in our database contain Pantothenic Acid. Open any to see its full ingredient list and every drug interaction we check.

+B Boost B-Complex by Shaklee Tablet Or Pill 240 Tablet(s) View ingredients & interactions +B Boost B-Complex by Shaklee Tablet Or Pill 120 Tablet(s) View ingredients & interactions 1 Vitamin + Mineral by Pioneer Tablet Or Pill 120 Vegetarian Tablet(s) View ingredients & interactions 1 Week Flush by MH Michael's Health Naturopathic Programs Tablet Or Pill 84 Vegetarian Tablet(s) View ingredients & interactions 1,000 mg Vitamin C Acai Berry by Emergen-C Powder 30 Packet(s) · 9 Ounce(s) · 261 Gram(s) View ingredients & interactions 1,000 mg Vitamin C Acai Berry by Emergen-C Powder 30 Packet(s) · 9 Oz(s) · 261 Gram(s) View ingredients & interactions 1,000 mg Vitamin C Acai Berry by Emergen-C Powder 0.3 OZ/Packet · 9.2 G/Packet · 30 Packet(s) View ingredients & interactions 1,000 mg Vitamin C Coconut-Pineapple by Emergen-C Powder 30 Packet(s) · 9.6 Ounce(s) · 270 Gram(s) View ingredients & interactions 1,000 mg Vitamin C Coconut-Pineapple by Emergen-C Powder 30 Packet(s) · 9.6 Oz(s) · 270 Gram(s) View ingredients & interactions 1,000 mg Vitamin C Cranberry Pomegranate by Emergen-C Powder 0.3 OZ/Packet · 8.3 G/Packet · 30 Packet(s) View ingredients & interactions 1,000 MG Vitamin C Cranberry-Pomegranate by Emergen-C Powder 0.3 oz. · 8.3 g View ingredients & interactions 1,000 mg Vitamin C Cranberry-Pomegranate by Emergen-C Powder 30 Packet(s) · 9 Oz(s) · 252 Gram(s) View ingredients & interactions 1,000 mg Vitamin C Key Lime by Emergen-C Powder 30 Packet(s) · 9.9 Ounce(s) · 282 Gram(s) View ingredients & interactions 1,000 mg Vitamin C Lemon Lime by Emergen-C Powder 0.3 OZ/Packet · 9.3 G/Packet · 30 Packet(s) View ingredients & interactions 1,000 mg Vitamin C Lemon Lime by Emergen-C Powder 0.3 oz. · 9.3 Gram(s) · 36 Packet(s) View ingredients & interactions 1,000 mg Vitamin C Lemon-Lime by Emergen-C Powder 0.33 Oz(s) · 9.4 Gram(s) View ingredients & interactions 1,000 mg Vitamin C Lemon-Lime by Emergen-C Powder View ingredients & interactions 1,000 mg Vitamin C Lemon-Lime by Emergen-C Powder 30 Packet(s) · 9.9 Oz(s) · 282 Gram(s) View ingredients & interactions 1,000 mg Vitamin C Lemon-Lime by Emergen-C Powder 30 Packet(s) · 9.9 Ounce(s) · 282 Gram(s) View ingredients & interactions 1,000 MG Vitamin C Mangosteen by Emergen-C Powder 0.3 oz. · 9.4 g View ingredients & interactions 1,000 mg Vitamin C Meyer Lemon by Emergen-C Powder 30 Packet(s) · 9.6 Oz(s) · 276 Gram(s) View ingredients & interactions 1,000 mg Vitamin C Orange by Equate Other (e.g. Tea Bag) 9.6 oz. · 273 Gram(s) View ingredients & interactions 1,000 mg Vitamin C Paradise Fruit by Emergen-C Powder 30 Packet(s) · 9.6 Oz(s) · 276 Gram(s) View ingredients & interactions 1,000 mg Vitamin C Pink Lemonade by Emergen-C Powder 30 Packet(s) · 9.9 Ounce(s) · 282 Gram(s) View ingredients & interactions
Pharmacist Counseling Corner

Pantothenic Acid: Common Questions

What is Pantothenic Acid used for, and does it work?
People use Pantothenic Acid for many reasons, but the evidence varies by use. According to the Natural Medicines database, there is at least some clinical evidence supporting Pantothenic Acid for Pantothenic acid deficiency. For most other uses it has been studied for, the evidence is currently insufficient to rate. See the graded list on this page, and always confirm with your pharmacist or doctor.
Does Pantothenic Acid interact with prescription medications?
We do not currently list any known drug interactions for Pantothenic Acid. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Pantothenic Acid interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Pantothenic Acid with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Pantothenic Acid interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Pantothenic Acid used for?
It is vitamin B5, an essential nutrient that helps your body turn food into energy. Its proven use is preventing or treating deficiency, while uses like acne and cholesterol support have only limited evidence.
Do I need a Pantothenic Acid supplement?
Most people do not, because the vitamin is found in nearly all foods and true deficiency is very rare. A balanced diet usually provides enough.
Is Pantothenic Acid safe to take?
It is generally safe for most people at normal amounts, and extra is usually removed by the kidneys. Very high doses can occasionally cause diarrhea or stomach upset.
Can I take it while pregnant or breastfeeding?
The amounts in food and standard prenatal vitamins are appropriate. Talk with your doctor before using high-dose supplements, since their safety during pregnancy and breastfeeding is not well studied.

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