Savin Tops Drug Interactions, Uses, Safety & More
What is this page for?
First and foremost: how Savin Tops interacts with medications. The heart of this page is the interaction list — every drug Savin Tops is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Savin Tops is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Savin Tops against your medication
Add one medicationDrugs that interact with Savin Tops
0 medications have a known interaction with Savin Tops, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Savin Tops. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Savin Tops combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Savin Tops: Uses, Safety & Side Effects
Savin Tops comes from the savin juniper, a shrub whose oil is highly toxic and was historically misused to bring on menstruation or end pregnancy. It is considered dangerous and is not recommended for any use; serious poisonings and deaths have been reported. Do not take it internally.
- Scientific name
- Juniperus sabina
- Family
- Cupressaceae
- Part used
- Young leafy branch tips (tops) and essential oil
- Common forms
- Dried herb, essential oil, tinctures, and topical preparations (all rarely used today)
- Inducing menstruation
- Attempting abortion (historical)
- Skin warts and growths
- Intestinal worms
- Joint and muscle aches (topical)
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Savin is a poisonous plant linked to severe toxicity and death, especially when taken internally.
It can cause abortion and severe harm to mother and baby and must never be used in pregnancy.
When used orally or topically. Savin tops are contraindicated in pregnancy because they can induce abortion, and fatal poisoning has occurred with as...
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Savin Tops are the young leafy branch tips of Juniperus sabina, a low-growing evergreen shrub in the cypress family. It is native to mountainous areas of central and southern Europe and parts of Asia, and is sometimes grown as an ornamental plant.
Historically, the tops and the strong-smelling essential oil were used in folk medicine. People mostly took it to try to start menstruation or to cause abortion, and applied it to the skin for warts and other growths. Today it is considered an obsolete and dangerous remedy, and it is not sold as a mainstream supplement.
Uses & effectiveness
There is no good scientific evidence that Savin Tops are safe or effective for any health condition. Most of what is known comes from old herbal traditions and from reports of poisonings, not from quality clinical studies.
In the past it was used to bring on a period, to try to end a pregnancy, to expel intestinal worms, and to treat skin warts. None of these uses are supported by reliable modern research, and the doses that were thought to be 'active' are dangerously close to doses that cause serious harm.
Because of its toxicity, health authorities and pharmacists do not recommend Savin Tops for any purpose.
How it works
Savin's effects are linked mainly to its essential oil, which contains compounds such as sabinene and sabinyl acetate. These substances are strong irritants to the gut, kidneys, and reproductive tissues.
The plant was believed to stimulate the uterus and cause contractions, which is why it was historically misused as an abortion-inducing agent. Its irritant nature also explains its old use against worms and on the skin. Much of this understanding comes from laboratory studies and case reports of poisoning rather than controlled research, and the same actions that were thought to be useful are what make it dangerous.
Safety & precautions
Savin Tops are poisonous and should not be taken internally. Swallowing the herb or its oil has caused severe gastrointestinal irritation, kidney damage, bleeding, seizures, and death. Even the topical use of strong preparations can cause serious skin and tissue damage.
Pregnancy: Never use Savin. It can trigger uterine contractions and abortion and has caused severe injury and death in both mothers and unborn babies.
Breastfeeding: Avoid completely, since the plant is toxic and its safety in nursing has not been established.
Children, older adults, and anyone with kidney, liver, or digestive problems are at especially high risk. If you have any product containing savin, do not use it, and talk with a pharmacist or doctor about safe alternatives.
Side effects
Reported effects of Savin Tops include nausea, vomiting, severe abdominal pain, and diarrhea. More serious poisoning can cause kidney injury, blood in the urine, low blood pressure, convulsions, coma, and death.
Applied to the skin, savin preparations can cause burning, redness, blistering, and irritation. Because the line between a 'small' dose and a poisonous dose is very narrow, there is no safe way to use this plant. Any signs of poisoning should be treated as a medical emergency—contact a poison control center or emergency services right away.
Savin Tops: Reported Adverse Effects
Documented safety reports on Savin Tops from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.
Savin tops are generally regarded as unsafe for use. Any benefits of therapy may not outweigh the risk of toxicity. Orally, symptoms of savin tops poisoning include nausea, nervousness, cardiac rhythm disorders, spasm, kidney damage, hematuria, central paralysis, unconsciousness, and death. Ingestion can also cause irritation of mucous membranes resulting in gastroenteritis, hepatitis, pneumonitis, and nephritis.
Topically, savin tops oil can cause skin irritation, blisters, and necrosis.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Hepatitis Hepatic
Orally, savin tops can cause toxicity. Hepatic symptoms of savin tops toxicity include hepatitis.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Nausea and vomiting Gastrointestinal
Orally, savin tops can cause toxicity. Gastrointestinal symptoms of savin tops toxicity include nausea and gastroenteritis.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Skin irritation Dermatologic
Topically, the volatile oil from savin tops can cause skin irritation, blisters, and necrosis. It can also cause severe irritation to mucous membranes.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Adverse-effects data: Natural Medicines, Therapeutic Research Center
Dosing
There is no established or safe dose of Savin Tops. Because the plant is highly toxic and the harmful dose is very close to any traditionally used amount, no responsible dosing recommendation can be given.
This herb is not recommended for self-treatment in any form. If you come across a product claiming to contain savin, do not take it, and check with a pharmacist or doctor before using it for any reason.
Savin Tops & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 2 references that drive our Savin Tops monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Savin Tops: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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