No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

100% Creatine Unflavored Ingredients & Drug Interactions

by Six Star Pro Nutrition

100% Creatine Unflavored label
See full label image
Powder Category: Non-nutrient/non-botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking 100% Creatine Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

100% Creatine Unflavored is a dietary supplement by Six Star Pro Nutrition with 1 active ingredient. Its ingredients are commonly taken for improving high-intensity exercise performance, building muscle strength and size, sports and athletic training.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of 100% Creatine Unflavored by Six Star Pro Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: creatine monohydrate. Creatine is a compound your muscles use for energy during high-intensity exercise and strength work.

There are no inactive ingredients listed for this unflavored powder form.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: build muscle strength and size.
  • We looked for evidence on: Athletic performance, Muscle breakdown, Muscle strength, Physical performance, Sarcopenia, Muscle hypertrophy — and 3 related terms.
  • The strongest evidence on file: Creatine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Creatine is rated "Possibly Effective" for Muscle strength, Sarcopenia.
  • Also on file: Creatine is rated "Insufficient Reliable Evidence To Rate" for Muscle breakdown, Physical performance.

Creatine monohydrate has possibly effective evidence for muscle strength, athletic performance, sarcopenia (age-related muscle loss), and certain rare brain disorders called cerebral creatine deficiency syndromes. For Huntington disease and osteopenia (low bone density), the evidence suggests it is possibly ineffective.

The evidence, ingredient by ingredient Creatine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Creatine is generally well tolerated in healthy adults when taken by mouth. The most common side effects are dehydration, diarrhea, stomach upset, muscle cramps, and water retention.

If you have kidney problems, be cautious and talk with your doctor before starting—creatine is processed by your kidneys, and safety data in that population is limited. Serious side effects are rare but case reports have mentioned kidney inflammation, kidney damage, muscle breakdown, and blood clots; these are not common.

Avoid creatine during pregnancy and while nursing—safety data hasn't been established enough to recommend use in either situation.

Side effects, ingredient by ingredient Creatine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we checked. That doesn't mean interactions can't happen, so if you're on any medications—especially ones that affect your kidneys or liver—check with your pharmacist before starting.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product may help build muscle strength and support athletic performance, particularly if you do resistance training. If you have kidney disease, are pregnant, or are breastfeeding, skip it and talk with your pharmacist.

For anyone else considering it, a conversation with your pharmacist or doctor is worth having—especially if you take any medications or have any health conditions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 100% Creatine Unflavored, straight from the product label.

Brand Six Star Pro Nutrition
Barcode (UPC) 631656703641
Net contents 14.11 Ounce(s); 400 Gram(s)
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 276708
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 100% Creatine Unflavored by Six Star Pro Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
10 Gram(s)
Servings per container
80
UPC/BARCODE
631656703641
IngredientAmount% DV
Creatine Monohydrate5 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

From America's # 1 Selling Body Building Supplement Brand 170 Million Bottles Sold!

20 years of excellence Leader in science A portion of every dollar to more research

Six Star 100% Creatine is from the makers of Muscle Tech, America's number one selling bodybuilding supplement brand, so you know it's a powerful formula that you can trust. Whether it's your first time at the gym or you’re a seasoned vet, pro athlete or just trying to gain that extra edge in your sport, everyone is an athlete, and every athlete needs to fuel their body with the best sports nutrition products available.

For more info, recipes, tips and to join the conversation, visit SixStarPro.com Facebook like us Twitter @SixStarPro Instagram sixstarpronutrition

Value size Elite Series from the makers of MuscleTech Research & Development

Packaged in the U.S.A.

America's #1 Selling Creatine Brand MuscleTech is America's #1 selling body building supplement brand based on cumulative wholesale dollar sales 2001 to present. Over 170 million bottles of MuscleTech and Six Star products combined have been sold.

Seals/Symbols

Guaranteed banned substance free cGMP Manufactured Manufactured according to cGMP standards, as is required for all dietary supplements.

Formulation

Guaranteed banned substance free

Formulated with a clinically proven dose of creatine monohydrate - the most researched form of creatine available - without any added ingredients, fillers or additives, Six Star 100% Creatine is the fuel you need to build muscle size, strength and performance, and it's engineered for all athletes.

Builds muscle size, strength & performance Clinically proven formula

100% creatine – no fillers, additives or artificial flavorings

Mixes easily, tasteless and odorless

Clinically proven to build muscle size, strength & performance Six Star 100% Creatine provides energy to muscle cells to improve recovery between sets, which leads to rapid increases in muscle performance, size and strength. In fact, in a 6-week study conducted at a leading university, subjects using the creatine in Six Star 100% Creatine combined with juice gained, on average, more lean muscle than subjects taking a placebo (5.9 lbs. vs. 0.4 lbs.). Six Star 100% Creatine is perfect for anyone looking for a high-quality, ultra-effective and clinically proven creatine formula. Plus it's tasteless, odorless and easy to mix. Trust Six Star 100% Creatine for optimum performance and results you can trust!

Builds lean muscle mass and enhances strength

No Fillers or Additives Zero Aspartame

Premium quality best value 80 servings

Six Star 100% Creatine is manufactured according to cGMP standards, as is required for all dietary supplements.

Made in China.

Mixes instantly Results based on core ingredient testing. See back for study details.

Formula

Six Star 100% Creatine is engineered for all athletes

Formulated with a clinically proven dose of creatine monohydrate - the most researched form of creatine available - without any added ingredients, fillers or additives, Six Star 100% Creatine is the fuel you need to build muscle size, strength and performance, and it's engineered for all athletes.

Six Star 100% Creatine Is For: Active men & women Strength trainers All athletes Fitness enthusiasts Body builders Endurance athletes

Benefits of Six Star 100% Creatine: 5g of the most researched form of creatine per serving 100% creatine - no fillers, additives or artificial flavorings

5 g total ultra-pure creatine

100% ultra-pure creatine monohydrate

Suggested/Recommended/Usage/Directions

For best results, stack with: Use 30 to 45 minutes before workout Pre-workout powder engineered to enhance muscle performance, increase energy and get you pumped while you train. Pre & post-workout between meals Advanced whey protein formula designed to help build muscle and strength.

Directions: Mix 1 serving (1 scoop) with water, fruit juice or your favorite pre- or post-workout drink. Six Star researchers recommend loading for the first 3 days. To load for 3 days, take 2 servings twice a day. On days of your workout, take 2 servings before your workout and 2 servings after your workout. On days that you don’t work out, take at any other time of the day. After the first 3 days of loading, take 1 serving twice a day. As with all creatine products, maintain an adequate state of hydration during use.

How to Take 100% Creatine: Stir or Shake Tip: Mix with water, fruit juice, or your favorite pre- or post-workout drink.

FDA Statement of Identity

Dietary Supplement

Precautions

Warning: Do not use if pregnant or nursing.

Consult a medical doctor before starting any diet or exercise program.

Keep out of reach of children.

Do not use if packaging has been tampered with.

Storage

Store in a cool, dry place (60 degrees F to 80 degrees F).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Copyright 2018.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

100% Creatine Unflavored by Six Star Pro Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

100% Creatine Unflavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in 100% Creatine Unflavored by Six Star Pro Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container80 Amounts shown are per serving.

Creatine Monohydrate

No known
interactions
5 Gram(s) per serving

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity ac...

Creatine Monohydrate monograph & interactions
Interaction report

100% Creatine Unflavored by Six Star Pro Nutrition Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in 100% Creatine Unflavored. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for 100% Creatine Unflavored, from the product label.

Six Star Pro Nutrition

See all Six Star Pro Nutrition products
Name
Iovate Health Sciences U.S.A. Inc.
Street Address
1105 Market Street, Suite 1330
City
Wilmington
State
DE
ZipCode
19801
Web Address
SixStarPro.com
Pharmacist Counseling Corner

100% Creatine Unflavored by Six Star Pro Nutrition: Common Questions

Does 100% Creatine Unflavored by Six Star Pro Nutrition interact with any medications?
We do not currently list a known interaction for the mapped ingredients in 100% Creatine Unflavored. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
100% Creatine Unflavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is creatine monohydrate and what does it do?
Creatine monohydrate is a compound your muscles naturally produce and use for energy during intense exercise. It's been shown to possibly help with muscle strength, athletic performance, and age-related muscle loss. Supplementing with it may help your muscles work harder and recover better during strength training.
Will creatine cause me to gain weight?
Creatine can cause water retention—meaning your muscles may hold more water, which shows up on the scale. Some people in trials experienced edema (swelling), though it often resolved over time. That water weight is not the same as gaining fat or muscle tissue.
Can I take creatine if I have kidney problems?
If you have kidney issues, you should be cautious. Creatine is processed by your kidneys, so the safety data in people with kidney disease is limited. Talk with your doctor or pharmacist before starting.
Is creatine safe during pregnancy or while breastfeeding?
No. Safety during pregnancy has not been established, so it's best avoided if you're pregnant. There isn't enough safety information for nursing mothers either, so avoid use while breastfeeding.
What are the most common side effects?
The most common ones are dehydration, diarrhea, stomach upset, muscle cramps, and water retention. These are usually mild and often go away as your body adjusts. Drink plenty of water to help prevent dehydration.
Does this powder have any fillers or other ingredients?
No—this is pure creatine monohydrate with no inactive ingredients listed. It's unflavored, so it has no sweeteners or flavoring agents either.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 100% Creatine Unflavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

100% Creatine Unflavored label
Go deeper

The Full Monographs Behind 100% Creatine Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Creatine

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...

Read the full Creatine monograph →
Sources

Sources & How We Checked

100% Creatine Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 86 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Creatine 86 references
  1. Koshy KM, Griswold E, Schneeberger EE. Interstitial nephritis in a patient taking creatine. N Engl J Med 1999;340:814-5. PubMed
  2. Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3.
  3. Greenhaff P. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;352:233-4. PubMed
  4. Vandenberghe K, Goris M, Van Hecke P, et al. Long-term creatine intake is beneficial to muscle performance during resistance training (abstract). J Appl Physiol 1997;83:2055-63. PubMed
  5. Hultman E, Soderlund K, Timmons JA, et al. Muscle creatine loading in men. J Appl Physiol 1996;81:232-7. PubMed
  6. Pritchard NR, Kalra PA. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;351:1252-3. PubMed
  7. Poortmans JR, Auquier H, Renaut V, et al. Effect of short-term creatine supplementation on renal responses in men (abstract). Eur J Appl Physiol Occup Physiol 1997;76:566-7. PubMed
  8. Poortmans JR, Francaux M. Long-term oral creatine supplementation does not impair renal function in healthy athletes. Med Sci Sports Exerc 1999;31:1108-10. PubMed
  9. Mihic S, MacDonald JR, McKenzie S, Tarnopolsky MA. Acute creatine loading increases fat-free mass, but does not affect blood pressure, plasma creatinine, or CK activity in men and women. Med Sci Sports Exerc 2000;32:291-6. PubMed
  10. Rawson ES, Wehnert ML, Clarkson PM. Effects of 30 days of creatine ingestion in older men. Eur J Appl Physiol Occup Physiol 1999;80:139-44. PubMed
  11. Earnest CP, Almada AL, Mitchell TL. High-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and women. Clin Sci (Colch) 1996;91:113-8. PubMed
  12. Juhn MS. Oral creatine supplementation. Separating fact from hype. Phys Sportsmed 1999;27:47-50,53-54,56,61,89. PubMed
  13. Juhn MS, O'Kane JW, Vinci DM. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. J Am Diet Assoc 1999;99:593-5.
  14. Green AL, Hultman E, Macdonald IA, et al. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans. Am J Physiol 1996;271:E821-6. PubMed
  15. Balsom PD, Soderlund K, Sjodin B, Ekblom B. Skeletal muscle metabolism during short duration high-intensity exercise: influence of creatine supplementation. Acta Physiol Scand 1995;154:303-10. PubMed
  16. Snow RJ, McKenna MJ, Selig SE, et al. Effect of creatine supplementation on sprint exercise performance and muscle metabolism. (abstract) J Appl Physiol 1998;84:1667-73. PubMed
  17. McNaughton LR, Dalton B, Tarr J. The effects of creatine supplementation on high-intensity exercise performance in elite performers. (abstract) Eur J Appl Physiol Occup Physiol 1998;78:236-40. PubMed
  18. Groeneveld GJ, Veldink JH, van der Tweel I, et al. A randomized sequential trial of creatine in amyotrophic lateral sclerosis. Ann Neurol 2003;53:437-45. . PubMed
  19. Robinson SJ. Acute quadriceps compartment syndrome and rhabdomyolysis in a weight lifter using high-dose creatine supplementation. J Am Board Fam Pract 2000;13:134-7. PubMed
  20. Kammer RT. Lone atrial fibrillation associated with creatine monohydrate supplementation. Pharmacotherapy 2005;25:762-4. PubMed
  21. Gualano B, Ugrinowitsch C, Novaes RB, et al. Effects of creatine supplementation on renal function: a randomized, double-blind, placebo-controlled clinical trial. Eur J Appl Physiol 2008;103:33-40. PubMed
  22. Pfeffer, G., Majamaa, K., Turnbull, D. M., Thorburn, D., and Chinnery, P. F. Treatment for mitochondrial disorders. Cochrane Database.Syst.Rev. 2012;4:CD004426. PubMed
  23. Boos, C. J., White, S. H., Bland, S. A., and McAllister, P. D. Dietary supplements and military operations: caution is advised. J R.Army Med Corps 2010;156(1):41-43. PubMed
  24. Kreider, R. B. Dietary supplements and the promotion of muscle growth with resistance exercise. Sports Med 1999;27(2):97-110. PubMed
  25. Juhn, M. S., O'Kane, J. W., and Vinci, D. M. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. J Am.Diet.Assoc 1999;99(5):593-595.
  26. Volek, J. S., Duncan, N. D., Mazzetti, S. A., Putukian, M., Gomez, A. L., and Kraemer, W. J. No effect of heavy resistance training and creatine supplementation on blood lipids. Int J Sport Nutr.Exerc.Metab 2000;10(2):144-156. PubMed
  27. Robinson, T. M., Sewell, D. A., Casey, A., Steenge, G., and Greenhaff, P. L. Dietary creatine supplementation does not affect some haematological indices, or indices of muscle damage and hepatic and renal function. Br.J Sports Med 2000;34(4):284-288. PubMed
  28. Tarnopolsky, M. A. Potential benefits of creatine monohydrate supplementation in the elderly. Curr.Opin.Clin Nutr.Metab Care 2000;3(6):497-502. PubMed
  29. Tarnopolsky, M. A. and MacLennan, D. P. Creatine monohydrate supplementation enhances high-intensity exercise performance in males and females. Int J Sport Nutr.Exerc.Metab 2000;10(4):452-463. PubMed
  30. Arciero, P. J., Hannibal, N. S., III, Nindl, B. C., Gentile, C. L., Hamed, J., and Vukovich, M. D. Comparison of creatine ingestion and resistance training on energy expenditure and limb blood flow. Metabolism 2001;50(12):1429-1434. PubMed
  31. Chrusch, M. J., Chilibeck, P. D., Chad, K. E., Davison, K. S., and Burke, D. G. Creatine supplementation combined with resistance training in older men. Med Sci.Sports Exerc. 2001;33(12):2111-2117. PubMed
  32. Cox, G., Mujika, I., Tumilty, D., and Burke, L. Acute creatine supplementation and performance during a field test simulating match play in elite female soccer players. Int J Sport Nutr.Exerc.Metab 2002;12(1):33-46. PubMed
  33. Kilduff, L. P., Vidakovic, P., Cooney, G., Twycross-Lewis, R., Amuna, P., Parker, M., Paul, L., and Pitsiladis, Y. P. Effects of creatine on isometric bench-press performance in resistance-trained humans. Med Sci.Sports Exerc. 2002;34(7):1176-1183. PubMed
  34. Brose, A., Parise, G., and Tarnopolsky, M. A. Creatine supplementation enhances isometric strength and body composition improvements following strength exercise training in older adults. J Gerontol A Biol.Sci.Med Sci. 2003;58(1):11-19. PubMed
  35. Volek, J. S., Ratamess, N. A., Rubin, M. R., Gomez, A. L., French, D. N., McGuigan, M. M., Scheett, T. P., Sharman, M. J., Hakkinen, K., and Kraemer, W. J. The effects of creatine supplementation on muscular performance and body composition responses to
  36. Tyler, T. F., Nicholas, S. J., Hershman, E. B., Glace, B. W., Mullaney, M. J., and McHugh, M. P. The effect of creatine supplementation on strength recovery after anterior cruciate ligament (ACL) reconstruction: a randomized, placebo-controlled, double-b DOI
  37. Groeneveld, G. J., Beijer, C., Veldink, J. H., Kalmijn, S., Wokke, J. H., and van den Berg, L. H. Few adverse effects of long-term creatine supplementation in a placebo-controlled trial. Int J Sports Med 2005;26(4):307-313. PubMed
  38. Astorino, T. A., Marrocco, A. C., Gross, S. M., Johnson, D. L., Brazil, C. M., Icenhower, M. E., and Kneessi, R. J. Is running performance enhanced with creatine serum ingestion? J Strength.Cond.Res 2005;19(4):730-734. PubMed
  39. Cramer, J. T., Stout, J. R., Culbertson, J. Y., and Egan, A. D. Effects of creatine supplementation and three days of resistance training on muscle strength, power output, and neuromuscular function. J Strength.Cond.Res 2007;21(3):668-677. PubMed
  40. Young, P., De, Jonghe P., Stogbauer, F., and Butterfass-Bahloul, T. Treatment for Charcot-Marie-Tooth disease. Cochrane.Database.Syst.Rev. 2008;(1):CD006052. PubMed
  41. Ostojic, S. M. and Ahmetovic, Z. Gastrointestinal distress after creatine supplementation in athletes: are side effects dose dependent? Res.Sports Med. 2008;16(1):15-22. PubMed
  42. Whitt, K. N., Ward, S. C., Deniz, K., Liu, L., Odin, J. A., and Qin, L. Cholestatic liver injury associated with whey protein and creatine supplements. Semin.Liver Dis. 2008;28(2):226-231. PubMed
  43. Koenig CA, Benardot D Cody M Thompson WR. Comparison of creatine monohydrate and carbohydrate supplementation on repeated jump height performance. J Strength Cond Res. 2008;22(4):1081-1086. PubMed
  44. Gordon, P. H., Cheung, Y. K., Levin, B., Andrews, H., Doorish, C., Macarthur, R. B., Montes, J., Bednarz, K., Florence, J., Rowin, J., Boylan, K., Mozaffar, T., Tandan, R., Mitsumoto, H., Kelvin, E. A., Chapin, J., Bedlack, R., Rivner, M., McCluskey, L.
  45. Bender, A., Samtleben, W., Elstner, M., and Klopstock, T. Long-term creatine supplementation is safe in aged patients with Parkinson disease. Nutr.Res. 2008;28(3):172-178. PubMed
  46. Parness, J. You're "hot" from pumping iron? Anesth.Analg. 2009;108(3):711-713. PubMed
  47. Gualano, B., Ferreira, D. C., Sapienza, M. T., Seguro, A. C., and Lancha, A. H., Jr. Effect of short-term high-dose creatine supplementation on measured GFR in a young man with a single kidney. Am.J.Kidney Dis. 2010;55(3):e7-e9. PubMed
  48. Saidi, H. and Mani, M. Severe metabolic acidosis secondary to coadministration of creatine and metformin, a case report. Am.J.Emerg.Med. 2010;28(3):388-6. PubMed
  49. Gualano, B., de, Salles Painelli, V, Roschel, H., Lugaresi, R., Dorea, E., Artioli, G. G., Lima, F. R., da Silva, M. E., Cunha, M. R., Seguro, A. C., Shimizu, M. H., Otaduy, M. C., Sapienza, M. T., da Costa, Leite C., Bonfa, E., and Lancha Junior, A. H.
  50. Neves, M., Jr., Gualano, B., Roschel, H., Lima, F. R., Lucia, de Sa-Pinto, Seguro, A. C., Shimizu, M. H., Sapienza, M. T., Fuller, R., Lancha, A. H., Jr., and Bonfa, E. Effect of creatine supplementation on measured glomerular filtration rate in postmeno
  51. Gufford, B. T., Sriraghavan, K., Miller, N. J., Miller, D. W., Gu, X., Vennerstrom, J. L., and Robinson, D. H. Physicochemical characterization of creatine N-methylguanidinium salts. J.Diet.Suppl 2010;7(3):240-252.
  52. Lugaresi, R., Leme, M., de, Salles Painelli, V, Murai, I. H., Roschel, H., Sapienza, M. T., Lancha Junior, A. H., and Gualano, B. Does long-term creatine supplementation impair kidney function in resistance-trained individuals consuming a high-protein di
  53. Poortmans, J. R. and Francaux, M. Renal dysfunction accompanying oral creatine supplements. Lancet 7-18-1998;352(9123):234. PubMed
  54. Maganaris, C. N. and Maughan, R. J. Creatine supplementation enhances maximum voluntary isometric force and endurance capacity in resistance trained men. Acta Physiol Scand. 1998;163(3):279-287. PubMed
  55. Vandebuerie, F., Vanden Eynde, B., Vandenberghe, K., and Hespel, P. Effect of creatine loading on endurance capacity and sprint power in cyclists. Int J Sports Med 1998;19(7):490-495. PubMed
  56. Juhn, M. S. and Tarnopolsky, M. Oral creatine supplementation and athletic performance: a critical review. Clin J Sport Med 1998;8(4):286-297. PubMed
  57. Vandenberghe K, Van Hecke P, Van Leemputte M, and et al. Inhibition of muscle phosphocreatine resynthesis by caffeine after creatine loading. Med Sci Sports Exerc 1997;29(5 Supplement):249.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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