No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

7-Keto Ingredients & Drug Interactions

by Douglas Laboratories

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

7-Keto is a dietary supplement by Douglas Laboratories with 1 active ingredient. Its ingredients are commonly taken for weight loss and fat burning, boosting metabolism, supporting muscle mass.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of 7-Keto by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: 7-keto-DHEA, a compound related to DHEA (dehydroepiandrosterone), a hormone your body makes naturally. The capsules also contain microcrystalline cellulose and hydroxypropyl methylcellulose as inactive ingredients — these are standard binders and fillers that help hold the capsule together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see 7-keto-dhea's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: weight loss, metabolism, and body composition.
  • We looked for evidence on: Obesity, fat loss, metabolic support, body recomposition.
  • The closest evidence on file: 7-keto-dhea is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

The evidence for 7-keto-DHEA isn't established yet. Our data shows insufficient reliable evidence to rate it for any of the uses it's been studied for — PTSD, weight loss, depression, Raynaud syndrome, and aging.

That doesn't mean it won't work; it means the studies we have aren't robust enough to say either way.

The evidence, ingredient by ingredient 7-keto-dhea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use appears generally well tolerated in small studies, but long-term safety isn't well established, so we don't have a clear picture of what happens if you take it for months or years. Side effects reported in trials include nausea and vertigo — both uncommon.

One case report noted low red blood cell levels in someone taking the supplement, though the significance isn't clear. Because 7-keto-DHEA is hormone-related, the safety data advises against it during pregnancy, and there isn't enough information to know if it's safe while breastfeeding, so talk with your doctor or pharmacist about either of those situations.

Side effects, ingredient by ingredient 7-keto-dhea

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for 7-keto-DHEA. Still, if you take any medications, it's worth confirming with us or running them through the checker below before you begin.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

7-Keto might interest you if you're looking into DHEA alternatives, but the evidence for what it actually does isn't solid yet. The safety profile over the long term is murky.

Before you start, check with your pharmacist — especially if you're pregnant, nursing, or have any concerns about hormone supplements.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 7-Keto, straight from the product label.

Brand Douglas Laboratories
Barcode (UPC) 310539022368
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Apr 21, 2023
DSLD ID 273705
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 7-Keto by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
60
UPC/BARCODE
310539022368
IngredientAmount% DV
7-Keto100 mg--

Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults take 1 capsule twice daily or as directed by your healthcare professional.

Precautions

Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

Storage

Store in a cool, dry place.

Formulation

Gluten-free, Non-GMO

Healthy body composition As part of a healthy lifestyle involving consistent, moderate dietary restriction and regular exercise.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Scan to learn about our manufacturing excellence Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Formula

DHEA Metabolite

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

7-Keto is a trademark of Lonza or its affiliates. 7-Keto brand 7-oxo-dehydroepiandrosterone-3B-acetate.

See for yourself

7-Keto by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in 7-Keto by Douglas Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

7-Keto

No known
interactions
100 mg per serving

7-keto-DHEA is a lab-made metabolite of the hormone DHEA that is marketed mainly for weight loss and a faster metabolism. Unlike DHEA, it is not thoug...

7-Keto monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

7-Keto by Douglas Laboratories Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in 7-Keto. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for 7-Keto, from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Phone Number
1.800.245.4440
Web Address
www.douglaslabs.com
Pharmacist Counseling Corner

7-Keto by Douglas Laboratories: Common Questions

Does 7-Keto by Douglas Laboratories interact with any medications?
We do not currently list a known interaction for the mapped ingredients in 7-Keto. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
7-Keto contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take 7-Keto if I'm pregnant?
The safety data advises against it during pregnancy because there isn't enough information and hormone-related supplements are best avoided then. Talk with your doctor or pharmacist about whether it's right for you.
Is 7-Keto safe while breastfeeding?
There's no reliable safety information available, so it's best avoided while breastfeeding. Check with your pharmacist or doctor for personalized advice.
What side effects might I notice?
In clinical trials, a small number of people reported nausea or dizziness. One case report described low red blood cell levels, though its significance isn't clear. Long-term side effects aren't well studied yet.
Does 7-Keto actually work for weight loss or depression?
The evidence isn't established — we have insufficient reliable data to rate it for weight loss, depression, PTSD, or any of the other conditions it's been studied for. That means more or better research is needed.
How long can I safely take this?
Short-term use appears generally well tolerated in small studies, but long-term safety isn't established. If you're thinking of taking it for more than a few weeks, ask your pharmacist what we know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 7-Keto is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

7-Keto label
Go deeper

The Full Monographs Behind 7-Keto’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

7-Keto's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

7-keto-dhea 2 references
  1. Davidson M, Marwah A, Sawchuk RJ, et al. Safety and pharmacokinetic study with escalating doses of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy male volunteers. Clin Invest Med 2000;23:300-10..
  2. Zenk JL, Frestedt JL, Kuskowski MA. HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults. J Nutr Biochem 2007;18(9):629-34. PubMed

See these in context on the 7-keto-dhea monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring