No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

7-Keto DHEA 25 mg Ingredients & Drug Interactions

by Pure Encapsulations

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

7-Keto DHEA 25 mg is a dietary supplement by Pure Encapsulations with 1 active ingredient. Its ingredients are commonly taken for weight loss and fat burning, boosting metabolism, supporting muscle mass.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of 7-Keto DHEA 25 mg by Pure Encapsulations

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: 7-Keto DHEA, a compound derived from the hormone DHEA. The remaining ingredients — Plant Fiber, Cellulose, and Water — are inert materials that form the capsule and help deliver the active ingredient.

7-Keto DHEA is a metabolite of DHEA (the parent hormone your body naturally makes), but it doesn't convert back into estrogen or testosterone the way DHEA itself does.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient 7-keto-dhea product and its label doesn't state a use — see 7-keto-dhea's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for 7-Keto DHEA is not yet established in the data we hold. Studies have looked at its potential for post-traumatic stress disorder (PTSD), obesity, depression, Raynaud syndrome, and age-related concerns, but the evidence remains insufficient to rate it as effective for any of these uses.

If you're thinking about this for a specific health goal, that's a conversation worth having with your pharmacist or doctor.

The evidence, ingredient by ingredient 7-keto-dhea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use appears generally well tolerated in small studies, but long-term safety isn't well established — so we don't yet know what happens if you take it for months or years. A small number of trial participants reported nausea or dizziness, and one case report described changes in blood cell levels (hemoglobin and hematocrit) in someone taking 25 mg twice daily for a week, though the clinical significance isn't clear.

The safety data advises against use during pregnancy because it's a hormone-related supplement and we don't have enough information. Breastfeeding is also not recommended — there's no reliable safety information available.

Side effects, ingredient by ingredient 7-keto-dhea

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we could check in this product. Still, before you take it, ask your pharmacist to make sure it won't interact with anything you're on — especially if you take medications that affect your hormones.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

7-Keto DHEA might interest you if you're exploring hormone-related supplements for aging, mood, weight, or circulation concerns — but the evidence doesn't yet show it works for any of those. Pregnant or breastfeeding?

This one is best avoided. Ask your pharmacist to review it against your medications and health picture before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 7-Keto DHEA 25 mg, straight from the product label.

Brand Pure Encapsulations
Barcode (UPC) 766298004006
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Jul 18, 2023
DSLD ID 295133
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 7-Keto DHEA 25 mg by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
766298004006
IngredientAmount% DV
7-Keto DHEA25 mg--

Other ingredients: hypoallergenic Plant Fiber, Cellulose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 1-4 times daily, with meals, or as directed by a health professional.

Precautions

Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements

Formulation

Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Gluten-free, Non-GMO & Hypoallergenic

Gluten-free, Non-GMO & Hypoallergenic

Seals/Symbols

GFCO.org (Gluten-Free Certification Organization)

Formula

Unique DHEA metabolite

7-Keto brand 7-oxo-dehydroepiandrosterone-3B-acetate.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

7-Keto & logo are trademarks of Lonza or its affiliates. 7-Keto brand 7-oxo-dehydroepiandrosterone-3B-acetate.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

7-Keto DHEA 25 mg by Pure Encapsulations label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in 7-Keto DHEA 25 mg by Pure Encapsulations

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

7-Keto DHEA

No known
interactions
25 mg per serving

7-keto-DHEA is a lab-made metabolite of the hormone DHEA that is marketed mainly for weight loss and a faster metabolism. Unlike DHEA, it is not thoug...

7-Keto DHEA monograph & interactions

Other (inactive) ingredients: Hypoallergenic Plant Fiber, Cellulose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

7-Keto DHEA 25 mg by Pure Encapsulations Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in 7-Keto DHEA 25 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for 7-Keto DHEA 25 mg, from the product label.

Pure Encapsulations

See all Pure Encapsulations products
Name
Pure Encapsulations
Street Address
490 Boston Post Road
City
Sudbury
State
MA
Phone Number
1-800-753-2277
Web Address
www.PureEncapsulations.com
Pharmacist Counseling Corner

7-Keto DHEA 25 mg by Pure Encapsulations: Common Questions

Does 7-Keto DHEA 25 mg by Pure Encapsulations interact with any medications?
We do not currently list a known interaction for the mapped ingredients in 7-Keto DHEA 25 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
7-Keto DHEA 25 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is 7-Keto DHEA, and how is it different from regular DHEA?
7-Keto DHEA is a metabolite of DHEA — a compound your body naturally produces from the hormone DHEA. The key difference is that 7-Keto DHEA doesn't convert back into estrogen or testosterone like DHEA itself does, which is why some people view it as a different option.
Does 7-Keto DHEA actually work for weight loss, mood, or aging?
The evidence isn't established yet. Studies have looked at it for obesity, depression, PTSD, Raynaud syndrome, and aging, but the data we hold rates all of these as insufficient to recommend it. That doesn't mean it won't help you — it just means we don't have reliable evidence either way.
What side effects should I watch for?
Short-term use is generally well tolerated, but long-term safety isn't known. A small number of people in trials reported nausea or dizziness. One case report described changes in blood cell levels (hemoglobin and hematocrit) in someone taking 25 mg twice daily for a week, but the significance is unclear.
Can I take this while pregnant or breastfeeding?
No. The safety data advises against it during pregnancy because it's a hormone-related supplement and we don't have enough safety information. Breastfeeding is also not recommended — there's no reliable safety data available.
How long can I safely take this?
Short-term use appears generally well tolerated in small studies, but long-term safety isn't well established. If you're thinking about taking it for weeks or months, that's a good question to ask your pharmacist or doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 7-Keto DHEA 25 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

7-Keto DHEA 25 mg label
Go deeper

The Full Monographs Behind 7-Keto DHEA 25 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

7-Keto DHEA 25 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

7-keto-dhea 2 references
  1. Davidson M, Marwah A, Sawchuk RJ, et al. Safety and pharmacokinetic study with escalating doses of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy male volunteers. Clin Invest Med 2000;23:300-10..
  2. Zenk JL, Frestedt JL, Kuskowski MA. HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults. J Nutr Biochem 2007;18(9):629-34. PubMed

See these in context on the 7-keto-dhea monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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