No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Advanced Collagen Peptides with Bioton Unflavored Ingredients & Drug Interactions

by O Nutritions

Powder Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Advanced Collagen Peptides with Bioton Unflavored is a dietary supplement by O Nutritions with 2 active ingredients. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Advanced Collagen Peptides with Bioton Unflavored by O Nutritions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 2 active ingredients. D-Biotin is a B vitamin that supports hair, skin, and nail health.

Hydrolyzed Collagen Types I & III is a protein broken down into small peptides (pieces) that your body can absorb easily; it's the main structural protein in skin, joints, and connective tissue. There are no inactive fillers in this product.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: skin hydration, elasticity, hair, nails and joints.
  • We looked for evidence on: Aging skin, Alopecia areata, Androgenic alopecia, Atopic dermatitis (eczema), Biotin deficiency, Brittle nails — and 4 related terms.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Collagen Peptides is rated "Possibly Effective" for Aging skin, Dry skin.
  • Also on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Alopecia areata, Brittle nails.

D-Biotin is likely effective for biotin deficiency, though it shows insufficient evidence for alopecia areata (hair loss patches) and possibly ineffective for multiple sclerosis and seborrheic dermatitis (a scalp condition). Hydrolyzed Collagen is possibly effective for aging skin and dry skin, but possibly ineffective for muscle strength.

There isn't enough evidence yet to rate it for acne or athletic performance.

The evidence, ingredient by ingredient Biotin Collagen Peptides

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both ingredients are generally well tolerated. Biotin is considered safe even at fairly high doses because your body excretes excess in urine—though high-dose supplements warrant a quick conversation with your doctor.

Collagen peptides rarely cause mild side effects like nausea, upset stomach, diarrhea, or bloating. Biotin is likely safe in pregnancy and lactation at normal dietary and supplement amounts; discuss high-dose use with your doctor first.

Collagen peptides haven't been well studied in pregnancy or breastfeeding, so check with your doctor or pharmacist before use if you're pregnant or nursing.

Side effects, ingredient by ingredient Biotin Collagen Peptides

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, it's always smart to double-check your exact medications with the tool on this page—especially if you take a lot of drugs or have any questions.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This is a straightforward collagen and biotin blend with no documented medication interactions. If you're looking to support skin elasticity or biotin status, it's generally well tolerated.

Pregnant, nursing, or taking prescription medications? A quick chat with your pharmacist is worth the five minutes.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Advanced Collagen Peptides with Bioton Unflavored, straight from the product label.

Brand O Nutritions
Barcode (UPC) X0029K6N1Z
Net contents 9.8 Ounce(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 243923
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Advanced Collagen Peptides with Bioton Unflavored by O Nutritions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
20 Gram(s)
Maximum serving Sizes:
20 Gram(s)
Servings per container
14
UPC/BARCODE
X0029K6N1Z
IngredientAmount% DV
Calories17 Calorie(s)--
Calories from Fat0 Calorie(s)--
D-Biotin5 mg16667%
Hydrolyzed Collagen Types I & III20 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one (1) scoop daily.

Mixes well with food & water Water Juice Shakes Milk Tea Coffee Soup Oatmeal Cereal Yogurt

Precautions

Allergen Warning: This product does not contain allergens.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or mitigate any disease.

Formula

Benefits of collagen type I & III

Hydrolyzed Type I & III Collagen

Formulation

Youthful appearance Skin hydration Skin elasticity Hair & nail support Healthy bones & joints Healthy immune system Build muscles Improve circulation Healthy hair, skin & nails Grass fed & pasture raised

100% Grass fed beef

FDA Statement of Identity

Dietary Supplement

General Statements

14 Servings per container

Storage

Store in a cool, dry place

Seals/Symbols

GMP Good Manufacturing Practice Made in USA Made in FDA Registered Facility

See for yourself

Advanced Collagen Peptides with Bioton Unflavored by O Nutritions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Advanced Collagen Peptides with Bioton Unflavored by O Nutritions

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size20 Gram(s) Dosage formPowder Servings per container14 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

D-Biotin

No known
interactions
5 mg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

D-Biotin monograph & interactions

Hydrolyzed Collagen Types I & III

No known
interactions
20 Gram(s) per serving

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is...

Hydrolyzed Collagen Types I & III monograph & interactions
Interaction report

Advanced Collagen Peptides with Bioton Unflavored by O Nutritions Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Advanced Collagen Peptides with Bioton Unflavored. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Advanced Collagen Peptides with Bioton Unflavored, from the product label.

O Nutritions

See all O Nutritions products
Name
O Nutritions
State
HI
ZipCode
96789
Web Address
www.onutritions.com
Pharmacist Counseling Corner

Advanced Collagen Peptides with Bioton Unflavored by O Nutritions: Common Questions

Does Advanced Collagen Peptides with Bioton Unflavored by O Nutritions interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Advanced Collagen Peptides with Bioton Unflavored. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Advanced Collagen Peptides with Bioton Unflavored contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
Biotin at normal dietary and supplement amounts is likely safe in pregnancy and lactation, but discuss high-dose use with your doctor first. Collagen peptides haven't been well studied during pregnancy or breastfeeding, so there isn't enough safety data either way. Talk with your doctor or pharmacist about whether this product is right for you right now.
Will this help my hair or skin?
Biotin is likely effective if you're deficient in it, which supports hair and skin health. Collagen peptides are possibly effective for aging skin and dry skin. Results vary by person and take time—these aren't overnight fixes.
What are the side effects?
Both ingredients are rare culprits for side effects. Biotin at very high doses has rarely caused mild diarrhea. Collagen peptides may occasionally cause mild nausea, upset stomach, diarrhea, or bloating, but that's uncommon.
Is this safe for long-term use?
Yes—both ingredients are generally well tolerated over time. Biotin is especially safe because your body just clears the excess. If you're taking high-dose biotin, it's worth checking in with your doctor first.
Why are there only two ingredients?
This product is a simple blend of collagen peptides and biotin with no fillers or other additives. You're getting just the active ingredients, which some people prefer.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Advanced Collagen Peptides with Bioton Unflavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Advanced Collagen Peptides with Bioton Unflavored label
Sources

Sources & How We Checked

Advanced Collagen Peptides with Bioton Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Collagen Peptides 2 references
  1. Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
  2. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed

See these in context on the Collagen Peptides monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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