No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Aler-Gest Ingredients & Drug Interactions

by Douglas Laboratories

Tablet Or Pill Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Aler-Gest is a dietary supplement by Douglas Laboratories with 3 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Aler-Gest by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Aler-Gest contains three active digestive enzymes. Lipase breaks down dietary fats, protease breaks down proteins, and amylase breaks down starches — together they're meant to support digestion.

The tablet also contains several inactive ingredients including sorbitol, cellulose, vegetable stearate, silica, alfalfa powder, natural peppermint flavor, and date powder.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: digestive enzyme support for fat protein starch digestion.
  • We looked for evidence on: Dyspepsia, pancreatic insufficiency, indigestion, malabsorption.
  • The closest evidence on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia (Natural Medicines).

The evidence for these enzymes is limited. Lipase and protease have been studied for inflammatory bowel disease (IBD) and dyspepsia (indigestion), but the data we hold is marked insufficient to rate their usefulness for those conditions.

Amylase's effectiveness ratings are not on file. If you're considering this product for a specific digestive issue, talk it over with your doctor or pharmacist — they can help you weigh whether enzyme supplements make sense for your situation.

The evidence, ingredient by ingredient Lipase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase and protease are generally well tolerated in adults, though protease may occasionally cause digestive upset or allergic reactions. There's little safety data on either ingredient during pregnancy or breastfeeding — if you're pregnant or nursing, talk with your doctor or pharmacist before taking this product.

One caution: recombinant human bile salt-stimulated lipase (a specific form used in premature infants) has caused serious gastrointestinal problems in that population, so this product is not for use in infants.

Side effects, ingredient by ingredient Lipase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, we don't hold interaction data for amylase, so run your full medication list through the search tool on this page to be safe.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Aler-Gest is a basic digestive enzyme blend. If you have a normal stomach and want to try digestive support, the enzymes we checked show no known medication interactions and are generally well tolerated.

If you have a serious digestive condition, are pregnant or breastfeeding, or take any medications, check with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Aler-Gest, straight from the product label.

Brand Douglas Laboratories
Barcode (UPC) 745287110027
Net contents 250 Tablet(s)
Market status On market
Date entered into DSLD Feb 26, 2014
DSLD ID 30909
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Aler-Gest by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
125
UPC/BARCODE
745287110027
IngredientAmount% DV
Amylase38 mg--
Lipase55 mg--
Protease10 mg--

Other ingredients: Sorbitol, Cellulose, Vegetable Stearate, Silica, alfalfa powder, natural Peppermint flavor, Date powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults chew or swallow 2 tablets with each meal or as directed by your healthcare professional.

Aler-GEST(TM) tablets can be chewed or swallowed whole.

Brand IP Statement(s)

Aler-Gest(TM) is a chewable dietary supplement of vegetable source enzymes which are specific for fats, proteins, and starches.

Precautions

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

Storage

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

General

AG2

FDA Statement of Identity

A Dietary Supplement

See for yourself

Aler-Gest by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Aler-Gest by Douglas Laboratories

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container125 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Amylase

38 mg per serving Form: Aspergillus oryzae

Lipase

No known
interactions
55 mg per serving Form: Aspergillus oryzae

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...

Lipase monograph & interactions

Protease

No known
interactions
10 mg per serving Form: Papaya

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Protease monograph & interactions

Other (inactive) ingredients: Sorbitol, Cellulose, Vegetable Stearate, Silica, Alfalfa powder, Natural Peppermint flavor, Date powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Aler-Gest by Douglas Laboratories Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Aler-Gest. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Aler-Gest, from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Phone Number
1.800.245.4440
Web Address
www.douglaslabs.com
Pharmacist Counseling Corner

Aler-Gest by Douglas Laboratories: Common Questions

Does Aler-Gest by Douglas Laboratories interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Aler-Gest. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Aler-Gest contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Aler-Gest if I'm pregnant?
There's not enough safety data on lipase or protease during pregnancy to know if they're okay. Talk with your doctor or pharmacist — they can help you decide whether to take it based on your individual situation.
What are proteases and what do they do?
Proteases are enzymes that break down protein in your food so your body can digest it. This product includes protease to help with that digestive process.
Does this work for digestive problems?
Lipase and protease have been studied for indigestion and inflammatory bowel disease, but the evidence is too weak to say they work for those conditions. We don't have effectiveness data for amylase on file.
Can protease cause an allergic reaction?
Protease may cause allergic reactions in some people, though they're uncommon. Allergic reactions have been reported mostly from occupational exposure to airborne enzyme dust, not from supplements. If you have a history of enzyme allergies or asthma, mention this product to your doctor or pharmacist first.
Is this safe to take while breastfeeding?
There's little safety data on lipase or protease during breastfeeding. Check with your doctor or pharmacist before using it — they can give you personalized advice.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Aler-Gest is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Aler-Gest label
Sources

Sources & How We Checked

Aler-Gest's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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