Benfotiamine 150 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Benfotiamine 150 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Benfotiamine 150 mg is a dietary supplement by Doctor's Best with 2 active ingredients. Its ingredients are commonly taken for diabetic nerve pain (neuropathy), supporting healthy nerve function, thiamine deficiency.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Benfotiamine 150 mg by Doctor's Best
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 2 active ingredients: benfotiamine (a fat-soluble form of thiamine, also called vitamin B1) and L-Leucine (an amino acid your body uses for muscle and protein metabolism). The capsule also holds inactive ingredients — hypromellose, microcrystalline cellulose, and silicon dioxide — which are fillers and capsule material.
Does it work?
Moderate evidence
Benfotiamine is possibly effective for diabetic nerve damage (neuropathy), meaning some evidence supports it but more research is needed. For diabetic kidney damage, the evidence suggests it's likely ineffective.
For other uses — alcohol use disorder, Alzheimer disease, and general peripheral nerve problems — there isn't enough reliable evidence to say whether it works. We hold no effectiveness rating for L-Leucine on this page.
How safe is it?
Well-documented data
Benfotiamine is generally well tolerated in the studies we have, but long-term safety isn't fully known, so the caution is to use it only if your doctor advises you to. In one clinical trial of 98 people taking 300–600 mg daily for 6 weeks, allergic skin reactions occurred in two people and mild stomach discomfort in six — rates no different from placebo.
Safety during breastfeeding hasn't been well studied, so caution is advised; pregnancy safety data isn't on file. Talk with your doctor or pharmacist about whether this is right for you if you're pregnant or breastfeeding.
Meds to double-check
No known interactions
No interactions are documented in our data for benfotiamine. That doesn't mean none could occur — it means the research we have doesn't show them.
Run your medications through the checker on this page to be sure, and ask your pharmacist if you have questions.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Benfotiamine may be worth considering if you have diabetic nerve damage and your doctor recommends it — the evidence points to possible benefit there. If you're pregnant, breastfeeding, or taking other medications, check with your doctor or pharmacist first.
Long-term safety isn't fully established, so it's not a supplement to take indefinitely without medical oversight.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Benfotiamine 150 mg, straight from the product label.
| Brand | Doctor's Best |
|---|---|
| Barcode (UPC) | 753950002692 |
| Net contents | 360 Veggie Cap(s) |
| Market status | On market |
| Date entered into DSLD | Jun 20, 2024 |
| DSLD ID | 302640 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Benfotiamine 150 mg by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Leucine | 12 mg | -- |
| Benfotiamine | 150 mg | -- |
Other ingredients: Hypromellose, Microcrystalline Cellulose, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Doctor's Best Benfotiamine is a fat-soluble form and highly bioavailable derivative of thiamin (Vitamin B1).
Benfotiamine with BenfoPure
Formulation
Benfotiamine is activated in the bloodstream, and is available in the body four times longer than water-soluble thiamin. Benfotiamine activates transketolase, a cellular enzyme essential for glucose metabolism pathway. It helps support the circulatory and nervous systems with radical-scavenging action against oxidative stress, providing a positive influence on Advanced Glycation End products (AGEs). Helps support healthy cells in the presence of blood glucose Helps support cellular processes fueled by glucose metabolites Helps radical-scavenging acting to support against oxidative stress
Helps support healthy glucose metabolism
Vegan
Non-GMO Gluten free Soy free
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
Doctor's Best Science-Based Nutrition
BenfoPure is a registered trademark of Hamari Chemicals Ltd., Japan.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Adult Use: Take 1 capsule daily, with or without food, or as recommended by a nutritionally informed physician.
Storage
Store in a cool dry place.
General Statements
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Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Benfotiamine 150 mg by Doctor's Best label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Benfotiamine 150 mg by Doctor's Best
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container360 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Leucine
Benfotiamine
No knowninteractions
Benfotiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) that the body may absorb more easily than regular thiamine. It is mostly studied...
Benfotiamine monograph & interactionsOther (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Benfotiamine 150 mg by Doctor's Best Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Benfotiamine 150 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Benfotiamine 150 mg, from the product label.
Doctor's Best
See all Doctor's Best products- Name
- Doctor's Best, Inc.
- City
- Tustin
- State
- California
- ZipCode
- 92780
- Phone Number
- (800) 777-2474
- Web Address
- www.drbvitamins.com
Benfotiamine 150 mg by Doctor's Best: Common Questions
Does Benfotiamine 150 mg by Doctor's Best interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does benfotiamine actually help with nerve damage from diabetes?
What are the side effects I should watch for?
Is it safe to take while breastfeeding?
What is L-Leucine doing in this formula?
Can I take this long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Benfotiamine 150 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Benfotiamine 150 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Benfotiamine 150 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 1 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Benfotiamine 1 reference
- Stracke H, Gaus W, Achenbach U, Federlin K, Bretzel RG. Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study. Exp Clin Endocrinol Diabetes 2008;116(10):600-5. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC