No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Benfotiamine 300 mg Ingredients & Drug Interactions

by LifeSeasons Essentials

Capsule Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Benfotiamine 300 mg is a dietary supplement by LifeSeasons Essentials with 1 active ingredient. Its ingredients are commonly taken for diabetic nerve pain (neuropathy), supporting healthy nerve function, thiamine deficiency.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Benfotiamine 300 mg by LifeSeasons Essentials

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Each capsule contains one active ingredient, benfotiamine, at 300 mg. The inactive ingredients are microcrystalline cellulose, hypromellose, silica, and rice bran, which are fillers and other non-active components that help make the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Benfotiamine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Benfotiamine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Diabetic neuropathy — rated "Possibly Effective" (Natural Medicines).

The evidence for benfotiamine varies by condition. For diabetic neuropathy (nerve damage caused by diabetes), it is rated possibly effective.

For diabetic nephropathy (kidney damage caused by diabetes), it is rated possibly ineffective. For alcohol use disorder, Alzheimer disease, and peripheral neuropathy, the reliable evidence is insufficient to rate, so we can't say whether it helps.

The evidence, ingredient by ingredient Benfotiamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Benfotiamine is generally well tolerated in studies, but long-term safety is not fully known. In one clinical study of 300 to 600 mg daily for 6 weeks, allergic skin reactions and slight stomach discomfort were reported, and the rate of side effects was not different from placebo.

Our safety notes say there isn't enough safety information to be sure, so they advise avoiding it unless your doctor advises otherwise. Safety while breastfeeding hasn't been well studied, so caution is advised.

Our pregnancy and lactation entry has no data on file, so talk with your doctor or pharmacist for advice on your situation.

Side effects, ingredient by ingredient Benfotiamine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for benfotiamine, the only ingredient in this product. That is not a guarantee that none exist, so check your exact prescriptions and over-the-counter products with the search tool on this page, and confirm with your own doctor or pharmacist before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Benfotiamine may be worth discussing with your doctor if you are looking at the diabetic neuropathy area, where the evidence is rated possibly effective. If you are pregnant, breastfeeding, or have a complex medication list, be extra careful and talk it over with your own doctor or pharmacist first.

Because long-term safety is not fully known, ask your healthcare provider whether it fits your needs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Benfotiamine 300 mg, straight from the product label.

Brand LifeSeasons Essentials
Barcode (UPC) 810034441508
Net contents 60 Veg Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 310462
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Benfotiamine 300 mg by LifeSeasons Essentials, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
810034441508
IngredientAmount% DV
Benfotiamine300 mg--

Other ingredients: Microcrystalline Cellulose, Hypromellose, Silica, Rice Bran

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take 2 capsules daily, with or without food.

Precautions

Caution: Use only as directed.

If pregnant, nursing, taking medication, or under medical supervision for any condition, consult a healthcare professional before use.

Keep out of reach of children.

Tamper evident. Do not use if printed safety seal under cap is broken or missing.

Storage

Store in a cool, dry place.

Formulation

No milk, eggs, fish, crustacean shellfish, tree nuts, wheat, peanuts, soy, colors, flavors, preservatives, or magnesium stearate.

Benfotamine supports: Glucose metabolism Nerve function Kidney protection Brain, heart, intestinal and muscle function

Superior bioavailability to support nerves & glucose metabolism.

Vegetarian.

Gluten-Free.

Made in USA with globally sourced ingredients.

Formula

About Benfotamine Benfotamine is a fat-soluble derivative of thiamine (Vitamin B1). It has superior bioavailability and penetration into nerve cells than water -soluble thiamine.

Fat soluble B1

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Copyright 2022

See for yourself

Benfotiamine 300 mg by LifeSeasons Essentials label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Benfotiamine 300 mg by LifeSeasons Essentials

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Benfotiamine

No known
interactions
300 mg per serving

Benfotiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) that the body may absorb more easily than regular thiamine. It is mostly studied...

Benfotiamine monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Silica, Rice Bran. These complete the product’s ingredient list but are not active constituents.

Interaction report

Benfotiamine 300 mg by LifeSeasons Essentials Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Benfotiamine 300 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Benfotiamine 300 mg, from the product label.

LifeSeasons Essentials

See all LifeSeasons Essentials products
Name
LifeSeasons
City
Kaysville
State
UT
ZipCode
84037
Phone Number
(877) 455-2826
Web Address
lifeseasons.com
Pharmacist Counseling Corner

Benfotiamine 300 mg by LifeSeasons Essentials: Common Questions

Does Benfotiamine 300 mg by LifeSeasons Essentials interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Benfotiamine 300 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Benfotiamine 300 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is benfotiamine safe during pregnancy?
Our pregnancy and lactation entry for benfotiamine has no data on file, so we can't say either way. Please talk with your doctor or pharmacist for advice that fits your situation.
What is benfotiamine used for?
Its most relevant rating is for diabetic neuropathy, where the evidence is rated possibly effective. For diabetic nephropathy, it is rated possibly ineffective, and for Alzheimer disease the reliable evidence is insufficient to rate.
What side effects has benfotiamine caused?
In one clinical study, allergic skin reactions and slight stomach discomfort were reported at rates not different from placebo. Its safety notes also say long-term safety is not fully known.
Does benfotiamine work for Alzheimer disease?
The reliable evidence for Alzheimer disease is insufficient to rate, so we can't say whether it helps. Your doctor is the best person to talk with about treatment options.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Benfotiamine 300 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Benfotiamine 300 mg label
Go deeper

The Full Monographs Behind Benfotiamine 300 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Benfotiamine 300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Benfotiamine 1 reference
  1. Stracke H, Gaus W, Achenbach U, Federlin K, Bretzel RG. Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study. Exp Clin Endocrinol Diabetes 2008;116(10):600-5. PubMed

See these in context on the Benfotiamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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