No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Benfotiamine Ingredients & Drug Interactions

by BulkSupplements.com

Powder Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Benfotiamine is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for diabetic nerve pain (neuropathy), supporting healthy nerve function, thiamine deficiency.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Benfotiamine by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: benfotiamine, a fat-soluble form of thiamine (vitamin B1). Benfotiamine is designed to be absorbed more readily by your body than standard thiamine, which is why it's used in supplements targeting nerve health and blood sugar concerns.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Benfotiamine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Benfotiamine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Diabetic neuropathy — rated "Possibly Effective" (Natural Medicines).

The evidence for benfotiamine is mixed and often limited. It's rated possibly effective for diabetic nerve pain (diabetic neuropathy), meaning there's some supportive research but it's not definitive.

For diabetic kidney damage (diabetic nephropathy), the evidence suggests it's probably not effective. For Alzheimer disease, alcohol use disorder, and general nerve pain unrelated to diabetes (peripheral neuropathy), we don't have enough reliable evidence to rate whether it works or not.

The evidence, ingredient by ingredient Benfotiamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Benfotiamine is generally well tolerated in the studies we have, though long-term safety hasn't been fully established. In one 6-week trial of 98 people taking 300–600 mg daily, a small number reported allergic skin reactions (two people) and mild stomach discomfort (six people) — rates no different from placebo.

Safety during pregnancy and breastfeeding hasn't been well studied, so the data advises caution; talk with your doctor or pharmacist before using it if you're pregnant or nursing.

Side effects, ingredient by ingredient Benfotiamine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we checked. Still, bring your current medications to your doctor or pharmacist before adding this supplement, just to confirm.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

If you're looking at benfotiamine for diabetic nerve pain, there's some evidence it may help, though it's not a sure thing. For other uses listed here, the evidence is either against it or not yet established.

Because long-term safety data is limited and pregnancy safety is unknown, it's worth discussing with your doctor or pharmacist before you start — especially if you're on any medications or planning pregnancy.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Benfotiamine, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) 849720026026
Net contents 250 Gram(s); 8.8 Ounce(s)
Market status On market
Date entered into DSLD Apr 23, 2024
DSLD ID 310992
Product type Vitamin
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Benfotiamine by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
150 mg
Maximum serving Sizes:
150 mg
Servings per container
1667
UPC/BARCODE
849720026026
IngredientAmount% DV
Benfotiamine150 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

BulkSupplements.com Clean & pure bulk supplements

Formulation

Free of: Sugar, soy, dairy, yeast, gluten, additives

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 150 mg once of twice daily with at least 8 oz of water, or as directed by a physician.

General Statements

Use an accurate milligram scale.

NewItem

Storage

Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Formula

Vitamin B1 (Thiamine)

See for yourself

Benfotiamine by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Benfotiamine by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size150 mg Dosage formPowder Servings per container1667 Amounts shown are per serving.

Benfotiamine

No known
interactions
150 mg per serving

Benfotiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) that the body may absorb more easily than regular thiamine. It is mostly studied...

Benfotiamine monograph & interactions
Interaction report

Benfotiamine by BulkSupplements.com Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Benfotiamine. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Benfotiamine, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
bulksupplements.com
Pharmacist Counseling Corner

Benfotiamine by BulkSupplements.com: Common Questions

Does Benfotiamine by BulkSupplements.com interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Benfotiamine. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Benfotiamine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does benfotiamine actually work for nerve pain?
For diabetic nerve pain specifically, there's some evidence it may help — that's why it's rated possibly effective. For other types of nerve pain or other conditions on the label, the evidence either isn't there yet or suggests it probably won't help. Talk with your doctor about whether it's worth trying for your situation.
What side effects should I watch for?
In studies, benfotiamine caused allergic skin reactions in a very small number of people and mild stomach discomfort in a few others — no more often than placebo. Most people tolerate it without problems, but long-term safety data is limited.
Is it safe to take if I'm pregnant or breastfeeding?
Safety during pregnancy and breastfeeding hasn't been well studied, so caution is advised. Talk with your doctor or pharmacist about whether this is right for you before starting it.
What exactly is benfotiamine and how is it different from regular B1?
Benfotiamine is a fat-soluble form of thiamine (vitamin B1) — meaning your body can absorb it more easily than standard thiamine. That's the main reason it's used in supplements.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Benfotiamine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Benfotiamine label
Go deeper

The Full Monographs Behind Benfotiamine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Benfotiamine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Benfotiamine 1 reference
  1. Stracke H, Gaus W, Achenbach U, Federlin K, Bretzel RG. Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study. Exp Clin Endocrinol Diabetes 2008;116(10):600-5. PubMed

See these in context on the Benfotiamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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