Berberine GlucoGOLD + By Whitaker Nutrition Overview & Drug Interactions

Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.

Chromium is a trace mineral that is found in small amounts in the human body. It is believed to play a role in the metabolism of carbohydrates, fats, and proteins. It is used as a dietary supplement for its purported ability to help with weight loss and blood sugar control. There is some evidence to suggest that chromium supplements may help to improve blood sugar control in people with type 2 diabetes, although the results of studies on this topic have been mixed. Some studies have found that chromium supplements can improve insulin sensitivity and reduce blood sugar levels in those with poorly controlled diabetes, while others have found no significant effects.

Berberine is a naturally-occurring compound that is found in several plants, including goldenseal, barberry, goldthread, phellodendron, and Oregon grape. It is known for its bitter taste and yellow color. It has been used for centuries in traditional medicine to treat a variety of conditions such as diabetes and high cholesterol. It is also thought to have antibacterial and anti-inflammatory effects.

Banaba (Lagerstroemia speciosa) is a plant species in the family Lythraceae. It is native to tropical regions of Asia, including the Philippines, India, and Malaysia. It is commonly used as a natural remedy to lower blood sugar levels in people with diabetes, and has also been used to treat high blood pressure, obesity, and kidney problems. Banaba contains a number of active compounds, including corosolic acid, ellagitannins, and lagerstroemin, which are believed to be responsible for its medicinal effects. Dietary supplements are generally made from the leaf of the plant. Patented extracts of banaba, such as Glucosol (i.e., Glucofit), are often utilized in dietary supplements as well.