No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Beta Alanine Extreme Ingredients & Drug Interactions

by Prolab

Beta Alanine Extreme label
See full label image
Capsule Category: Amino Acid/protein
No known interaction
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beta Alanine Extreme against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Beta Alanine Extreme is a dietary supplement by Prolab with 2 active ingredients. Its ingredients are commonly taken for skin conditions like eczema, anemia related to kidney disease, allergy and inflammation support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of Beta Alanine Extreme by Prolab

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 2 active ingredients. L-Histidine is an amino acid that the body uses for several roles, including immune function and the production of histamine.

CarnoSyn is a branded form of beta-alanine, another amino acid that builds up in muscle tissue and is studied mainly for athletic and physical performance. The capsules also contain gelatin, silica, magnesium stearate, and water as inactive ingredients — these are binders and fillers that hold the capsule together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: delay muscle fatigue and extend high intensity training.
  • We looked for evidence on: Athletic performance, Physical performance, Exercise-induced muscle breakdown, muscular endurance, lactic acid buffering, training capacity.
  • The strongest evidence on file: Beta-alanine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Beta-alanine is rated "Possibly Effective" for Physical performance.
  • Also on file: Beta-alanine is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle breakdown.

Beta-alanine (CarnoSyn) is possibly effective for athletic performance and physical performance — that's the strongest evidence we have. The data we hold doesn't establish effectiveness for age-related cognitive decline, chronic obstructive pulmonary disease (COPD), cognitive function, or menopausal symptoms.

For L-Histidine, the evidence is thinner. It's possibly effective for cholera.

For atopic dermatitis (eczema), rheumatoid arthritis, and kidney failure, there isn't enough reliable evidence to rate it.

The evidence, ingredient by ingredient Histidine Beta-alanine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-alanine is generally well tolerated in healthy adults, but it has a very common side effect: a harmless tingling sensation (paresthesia) and flushing of the skin. This usually starts on the scalp within 20 minutes of taking a dose, spreads across the body, and lasts about an hour.

How strong it is depends on the dose — it can be very mild at smaller doses or more noticeable at higher ones. The safety data advises against beta-alanine during pregnancy and while breastfeeding.

L-Histidine is likely safe in normal dietary amounts, but the safety of higher supplement doses isn't well established. There's enough data to say it's likely safe in pregnancy and lactation, but talk with your doctor or pharmacist before using it at supplement doses if you're pregnant or nursing.

Side effects, ingredient by ingredient Histidine Beta-alanine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, run your exact medications through the search tool on this page to make sure nothing unexpected shows up.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product is mainly for people looking to support athletic or physical performance with beta-alanine, the stronger of the two ingredients here. Expect some skin tingling and flushing — it's harmless but common.

If you're pregnant, breastfeeding, or on any medications, check with your own doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beta Alanine Extreme, straight from the product label.

Brand Prolab
Barcode (UPC) 750902202704
Net contents 240 Capsule(s)
Market status On market
Date entered into DSLD Dec 22, 2017
DSLD ID 77321
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beta Alanine Extreme by Prolab, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
120
UPC/BARCODE
750902202704
IngredientAmount% DV
L-Histidine75 mg, 300 mg--
CarnoSyn800 mg, 3200 mg--

Other ingredients: Gelatin, Silica, Magnesium Stearate, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Prolab Beta Alanine Extreme is a dynamic blend of CarnoSyn beta alanine and the amino acid L-Histidine designed to delay muscle fatigue and help extend high intensity training sessions.

General Statements

Beta alanine helps flood the muscles with the specialized amino acid carnosine to work as a buffer against lactic acid buildup. Carnosine is an amino acid found in Type II or "fast twitch" muscle fibers - the ones that produce explosive power. Buffering muscle acidity can help allow you to train at a higher intensity for a longer period of time before fatigue sets in and may yield a few more growth-stimulating reps.

With a loading dose of 6,400mg per day for 6 days.

Endurance Recovery Stamina Delays muscle fatigue

Brand IP Statement(s)

Prolab Beta Alanine Extreme also supports prolonged stamina and can help reduce muscle soreness both during and after training allowing for more efficient recovery time between sets and between workouts. You do your part. We'll do ours.

CarnoSyn Carnosine synthesizer Natural Alternatives International (NAI) is the owner of patents as listed on www.carnosyn. com and registered trademark CarnoSyn. 2016 Prolab Nutrition, Inc.

Performance simplified

Suggested/Recommended/Usage/Directions

This product is to be used in conjunction with a healthy diet and exercise regimen.

Directions: Take 2 capsules, four times daily, with a meal.

General

ITEM: 20270.795 F: 3001876 L: 2006728-16204

Seals/Symbols

Prolab Quality Assurance

FDA Statement of Identity

Dietary Supplement

Formulation

No: Milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans, yeast, artificial colors or flavors, added sugar or preservatives.

Storage

Store in a cool, dry place.

Precautions

Keep out of reach of children.

Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking prescription drugs, or are pregnant or lactating.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beta Alanine Extreme by Prolab label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beta Alanine Extreme label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beta Alanine Extreme by Prolab

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Histidine

No known
interactions
75 mg per serving

Histidine is an essential amino acid your body needs to build proteins and to make compounds like histamine and carnosine. Most people get enough from...

L-Histidine monograph & interactions

CarnoSyn

No known
interactions
800 mg per serving Form: Beta-Alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...

CarnoSyn monograph & interactions

Other (inactive) ingredients: Gelatin, Silica, Magnesium Stearate, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beta Alanine Extreme by Prolab Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Beta Alanine Extreme. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Beta Alanine Extreme, from the product label.

Prolab

See all Prolab products
Name
Prolab Nutrition LLC
City
Chatsworth
State
CA
ZipCode
91311
Phone Number
1-800-7765221
Web Address
www.prolab.com
Pharmacist Counseling Corner

Beta Alanine Extreme by Prolab: Common Questions

Does Beta Alanine Extreme by Prolab interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Beta Alanine Extreme. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Beta Alanine Extreme contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does beta-alanine actually do?
Beta-alanine builds up in your muscles and is studied mainly for athletic and physical performance. The evidence shows it's possibly effective for those uses. It's not established for cognitive decline, brain function, lung disease, or menopausal symptoms.
Will I get that tingling feeling everyone talks about?
Very likely, yes — it's the most common side effect. You'll probably feel pins and needles (paresthesia) and some flushing, starting on your scalp within about 20 minutes. It spreads across your body and usually lasts around an hour. The smaller your dose, the milder it tends to be, and at the lowest doses only about 1 in 4 people report it.
Is it safe to take while pregnant or nursing?
The beta-alanine ingredient has enough safety concerns in pregnancy and breastfeeding that the data advises against it. L-Histidine is likely safe in those situations, but you should talk with your doctor or pharmacist before using this product if you're pregnant or nursing, since it's a combination formula.
What is L-Histidine for?
L-Histidine is an amino acid your body uses for immune function and to make histamine, a chemical involved in many body processes. It's possibly effective for cholera, but there isn't enough reliable evidence for eczema, rheumatoid arthritis, or kidney problems.
Can I take this long-term?
Beta-alanine hasn't been studied for long-term use at high doses, so there's some uncertainty. L-Histidine at supplement doses hasn't been well studied either. If you're thinking about using this regularly, talk it over with your doctor or pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beta Alanine Extreme is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beta Alanine Extreme label
Go deeper

The Full Monographs Behind Beta Alanine Extreme’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Histidine

Histidine is an essential amino acid your body needs to build proteins and to make compounds like histamine and carnosine. Most people get enough from a normal diet, and good-quality researc...

Read the full Histidine monograph → Herb & supplement monograph

Beta-alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...

Read the full Beta-alanine monograph →
Sources

Sources & How We Checked

Beta Alanine Extreme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Histidine 3 references
  1. Histidine — MedlinePlus (U.S. National Library of Medicine) Source
  2. Amino Acids — MedlinePlus (U.S. National Library of Medicine) Source
  3. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

See these in context on the Histidine monograph →

Beta-alanine 13 references
  1. Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
  2. Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
  3. Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
  4. Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
  5. Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
  6. Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
  7. Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
  8. Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
  9. Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
  10. Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
  11. da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
  12. Varanoske AN, Hoffman JR, Church DD, et al. Comparison of sustained-release and rapid-release ß-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol. Amino Acids. PubMed
  13. Perim P, Gobbi N, Duarte B, et al. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. Eur J Sport Sci 2021. PubMed

See these in context on the Beta-alanine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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