Biotin 1000 mcg Ingredients & Drug Interactions
by Nature Made
What is this page for?
First and foremost: checking Biotin 1000 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Biotin 1000 mcg is a dietary supplement by Nature Made with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Biotin 1000 mcg by Nature Made
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: biotin (also called vitamin B7), a water-soluble B vitamin your body needs for converting food into energy and keeping your hair, skin, and nails healthy. The inactive ingredients are soybean oil, gelatin, glycerin, yellow beeswax, water, soy lecithin, and added colors — these are the capsule and fillers that hold the biotin together.
Does it work?
Strong evidence
Biotin is likely effective for biotin deficiency — the straightforward reason most people take it. For other uses like multiple sclerosis, seborrheic dermatitis (a scaly skin condition), and alopecia areata (patchy hair loss), the evidence either suggests it probably won't help (multiple sclerosis and seborrheic dermatitis) or isn't solid enough to say either way (alopecia areata).
If you're considering biotin for anything other than a confirmed deficiency, talk it over with your doctor first.
How safe is it?
Well-documented data
Biotin is generally well tolerated, even at fairly high doses, because your body excretes what it doesn't use in urine. Mild diarrhea has been rarely reported with high-dose use — one study noted transient mild diarrhea in two patients taking 300 mg daily.
There's one case report of a serious reaction (eosinophilic pleuropericarditis) in someone taking multiple supplements together, but the cause wasn't clear and no similar cases have been reported since. For pregnancy and breastfeeding, biotin is rated likely safe — normal dietary amounts and amounts in prenatal vitamins are fine.
However, if you're thinking about taking high-dose supplements, check with your doctor or pharmacist first.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredient in this product.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This biotin supplement is a straightforward choice if you have a confirmed biotin deficiency or want nutritional support for hair and nail health. It's gentle and well tolerated for most people.
If you're taking any medications, no documented interactions exist, but it's always smart to mention supplements to your own doctor or pharmacist, especially if you're pregnant or considering high-dose products.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 21, 2018.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Biotin 1000 mcg, straight from the product label.
| Brand | Nature Made |
|---|---|
| Barcode (UPC) | 031604042738 |
| Net contents | 120 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Sep 21, 2018 |
| DSLD ID | 180371 |
| Product type | Vitamin |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Biotin 1000 mcg by Nature Made, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Biotin | 1000 mcg | 333% |
Other ingredients: Soybean Oil, Gelatin, Glycerin, yellow Beeswax, Water, Soy Lecithin, Colors added
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
#1 pharmacist recommended
Biotin softgels are made to Nature Made's guaranteed purity and potency standards. Based on Pharmacy Times Survey of pharmacists recommending Letter Vitamin Supplements. USP has tested and verified ingredients, potency, and manufacturing process. USP sets official standards for dietary supplements. See www.uspverified.org.
General
List No. 4273 L200 Cat. A840 5A044
Suggested/Recommended/Usage/Directions
One per day
Suggested use: Take one softgel daily with a meal. For easier swallowing, take with water before and during ingestion.
Seals/Symbols
USP Dietary Supplement Verified
FDA Statement of Identity
Dietary Supplement
Formula
Biotin supports carbohydrate, protein & fat metabolism.
Contains: Soy.
Formulation
Colors derived from natural sources - No synthetic dyes No artificial flavors No preservatives No yeast or starch Gluten free
Storage
Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.
Precautions
Store in a cool, dry place, out of reach of children.
Do not use if imprinted seal under cap is broken or missing.
Contains: Soy.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Biotin 1000 mcg by Nature Made label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Biotin 1000 mcg by Nature Made
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Biotin
No knowninteractions
Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...
Biotin monograph & interactionsOther (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Yellow Beeswax, Water, Soy Lecithin, Colors added. These complete the product’s ingredient list but are not active constituents.
Biotin 1000 mcg by Nature Made Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Biotin 1000 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Biotin 1000 mcg, from the product label.
Nature Made
See all Nature Made products- Name
- Nature Made Nutritional Products
- City
- Mission Hills
- State
- CA
- ZipCode
- 91346-9606
- Phone Number
- 1-800-276-2878
- Web Address
- www.NatureMade.com
Biotin 1000 mcg by Nature Made: Common Questions
Does Biotin 1000 mcg by Nature Made interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will biotin help my hair grow?
Is it safe to take high-dose biotin?
Can I take biotin if I'm pregnant or breastfeeding?
What's the difference between biotin from food and a supplement?
Does biotin interfere with any blood tests?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Biotin 1000 mcg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Biotin 1000 mcg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Biotin 1000 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Biotin 4 references
- Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
- Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC