No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Biotin 300 mcg Ingredients & Drug Interactions

by Major

Tablet Or Pill Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Biotin 300 mcg is a dietary supplement by Major with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Biotin 300 mcg by Major

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: biotin, a B vitamin at 300 micrograms per dose. Biotin plays a role in converting food into energy and is involved in hair, skin, and nail health.

The tablet also contains several inactive ingredients — microcrystalline cellulose, stearic acid, vegetable magnesium stearate, croscarmellose sodium, silicon dioxide, and pharmaceutical glaze — which help form and stabilize the tablet.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports energy production.
  • We looked for evidence on: Biotin deficiency.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).

Biotin is likely effective for treating biotin deficiency, which can occur from certain medications or rare genetic conditions. For multiple sclerosis and seborrheic dermatitis (a flaky scalp condition), the evidence suggests it's probably not effective.

For hair loss (alopecia areata), there isn't enough reliable evidence yet to know whether it works.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at fairly high doses, because your body removes excess amounts through urine. At this 300 mcg dose, side effects are rare.

A very small number of people taking high-dose biotin (much higher than this product) reported mild diarrhea, and one isolated case report linked biotin combined with another supplement to an inflammatory reaction, though the exact cause was unclear. Normal dietary and supplement amounts like this one are considered safe, but if you're thinking about taking much higher doses down the road, talk it over with your doctor first.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This biotin supplement is straightforward: it's a single B vitamin at a modest dose, generally well tolerated, and useful if you have a biotin deficiency. If you're taking it for hair, skin, or nails without a confirmed deficiency, the evidence doesn't yet support that use.

Check with your doctor or pharmacist before starting, especially if you're pregnant, nursing, or taking any medications — though no interactions are documented, they'll know your full health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 28, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Biotin 300 mcg, straight from the product label.

Brand Major
Barcode (UPC) 309045433607
Net contents 100 Tablet(s)
Market status On market
Date entered into DSLD May 28, 2019
DSLD ID 202028
Product type Vitamin
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Biotin 300 mcg by Major, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
309045433607
IngredientAmount% DV
Biotin300 mcg100%

Other ingredients: Microcrystalline Cellulose, Stearic Acid, Vegetable Magnesium Stearate, Croscarmellose Sodium, Silicon Dioxide, Pharmaceutical Glaze

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

Re-Order No. 700253 M-92 Rev 07/15

General Statements

Potency guaranteed Supports energy production

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, take one (1) tablet daily, preferably with a meal.

Precautions

As a remainder, discuss the supplements and medications you take with your health care providers. Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Tamper resistant: Do not use if seal under cap is broken or missing.

Formula

Biotin is essential for the intermediate metabolism of carbohydrates, proteins and fats.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Free of: Yeast, wheat, milk or milk derivatives, lactose, sugar, preservatives, soy, artificial color, artificial flavor, sodium (less than 5 mg per serving).

Storage

Store in a dry place and avoid excessive heat.

See for yourself

Biotin 300 mcg by Major label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Biotin 300 mcg by Major

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Biotin

No known
interactions
300 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Stearic Acid, Vegetable Magnesium Stearate, Croscarmellose Sodium, Silicon Dioxide, Pharmaceutical Glaze. These complete the product’s ingredient list but are not active constituents.

Interaction report

Biotin 300 mcg by Major Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Biotin 300 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Biotin 300 mcg, from the product label.

Major

See all Major products
Name
Major Pharmaceuticals
Street Address
31778 Enterprise Drive
City
Livonia
State
MI
ZipCode
48150
Phone Number
(800) 616-2471
Pharmacist Counseling Corner

Biotin 300 mcg by Major: Common Questions

Does Biotin 300 mcg by Major interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Biotin 300 mcg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Biotin 300 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is biotin safe to take while pregnant or breastfeeding?
Biotin at normal dietary and supplement amounts is considered likely safe during pregnancy and lactation. Amounts from food and prenatal vitamins are appropriate, but if you're thinking about taking high-dose supplements, check with your doctor first.
Can biotin help with hair loss?
For alopecia areata (a specific type of hair loss), there isn't enough reliable evidence to say whether biotin works. If hair loss is your reason for taking it, talk with your doctor about whether there's evidence for your particular situation.
What does biotin actually do in the body?
Biotin is a B vitamin that helps your body convert food into energy and plays a role in the health of your hair, skin, and nails. It's essential if you have a biotin deficiency, though most people get enough from food.
Are there any side effects from this dose of biotin?
At 300 mcg, side effects are rare. Very high doses have been rarely linked to mild diarrhea in a small number of people, but this product's dose is well below those levels.
Does this tablet have any fillers?
Yes, it contains several inactive ingredients like microcrystalline cellulose, stearic acid, and silicon dioxide that help form the tablet — these are standard and help with stability and absorption.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Biotin 300 mcg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Biotin 300 mcg label
Go deeper

The Full Monographs Behind Biotin 300 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Biotin 300 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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