No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Biotin 300 mcg Ingredients & Drug Interactions

by Natural Factors

Tablet Or Pill Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Biotin 300 mcg is a dietary supplement by Natural Factors with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Biotin 300 mcg by Natural Factors

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: biotin, a B vitamin at a dose of 300 micrograms per tablet. Biotin supports energy metabolism and healthy hair, skin, and nails.

The remaining ingredients — microcrystalline cellulose and magnesium stearate — are inactive fillers and binders that help form and stabilize the tablet.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Biotin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports hair and nail health.
  • We looked for evidence on: Alopecia areata, Brittle nails, hair thinning, nail strength.
  • The closest evidence on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Alopecia areata (Natural Medicines).
  • Also on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Brittle nails.

Biotin is likely effective for biotin deficiency itself. For other uses — including multiple sclerosis, seborrheic dermatitis (a scalp condition), and hair loss (alopecia areata) — the evidence doesn't support it.

Biotin has insufficient reliable evidence for alopecia areata, and it's possibly ineffective for both MS and seborrheic dermatitis.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at higher doses, because your body removes excess amounts through urine. At very high doses — much higher than the 300 mcg in this product — mild diarrhea has been rarely reported.

One isolated case report linked a much larger dose of biotin (10 mg daily, not this dose) combined with pantothenic acid to a serious lung and heart inflammation, but it's unclear whether biotin was responsible, and no similar cases have been reported since. Biotin is rated likely safe in pregnancy and lactation; normal dietary and supplement amounts are considered appropriate.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Even so, talk with your own doctor or pharmacist before starting this product.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

If you have biotin deficiency, this dose can help restore normal levels. If you're taking it for hair, skin, or nails, or for a neurological condition like MS, the evidence doesn't support that use.

This product doesn't interact with medications we have data for, but talk with your doctor or pharmacist before starting it — especially if you're pregnant, breastfeeding, or considering a high-dose biotin supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Biotin 300 mcg, straight from the product label.

Brand Natural Factors
Barcode (UPC) 068958012605
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 220267
Product type Vitamin
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Biotin 300 mcg by Natural Factors, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
068958012605
IngredientAmount% DV
Biotin300 mcg1000%

Other ingredients: Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

isura Non-GMO - Mass Spec Documentation Lab tested

Purity & Potency Guaranteed

Suggested/Recommended/Usage/Directions

Suggested Usage: 1 tablet per day or as directed by a health professional.

Precautions

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

Formula

Biotin (vitamin B7) is essential to the metabolism of carbohydrates and fats, and aids in the production and utilization of amino acids. Biotin supplementation has been shown to increase the strength of nails and promote healthy hair.

Formulation

Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.

Suitable for vegetarians/vegans.

Promotes healthy hair & nails

Storage

For freshness, store in a cool, dry place.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Product of Canada Recyclable container and label.

FDA Statement of Identity

Dietary Supplement

See for yourself

Biotin 300 mcg by Natural Factors label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Biotin 300 mcg by Natural Factors

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Biotin

No known
interactions
300 mcg per serving Form: Vitamin B7

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Biotin 300 mcg by Natural Factors Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Biotin 300 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Biotin 300 mcg, from the product label.

Natural Factors

See all Natural Factors products
Name
Natural Factors Canada
Pharmacist Counseling Corner

Biotin 300 mcg by Natural Factors: Common Questions

Does Biotin 300 mcg by Natural Factors interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Biotin 300 mcg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Biotin 300 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is biotin safe to take during pregnancy or while breastfeeding?
Biotin is rated likely safe in pregnancy and lactation. Normal dietary amounts and typical supplement doses are considered appropriate, though biotin from food and prenatal vitamins is the standard approach.
Will biotin help my hair grow or improve my skin?
The evidence doesn't support using biotin for hair loss or skin conditions. Biotin is only rated likely effective for actual biotin deficiency, which is rare in people eating a varied diet.
Can I take a much higher dose of biotin if a little is good?
No — stick with normal dietary and supplement amounts, and discuss any high-dose biotin products with your doctor first. Very high doses are rarely linked to mild diarrhea, and one case report involved even higher amounts combined with other supplements.
What is biotin, and what does it do?
Biotin is a B vitamin that supports energy production and is involved in the health of hair, skin, and nails. Your body can't store excess biotin — it removes it through urine, which is why it's generally well tolerated even at fairly high doses.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Biotin 300 mcg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Biotin 300 mcg label
Go deeper

The Full Monographs Behind Biotin 300 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Biotin 300 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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