No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Biotin 500 mcg Ingredients & Drug Interactions

by The Vitamin Shoppe

Capsule Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Biotin 500 mcg is a dietary supplement by The Vitamin Shoppe with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Biotin 500 mcg by The Vitamin Shoppe

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: biotin, a B vitamin your body needs to break down food and produce energy. The rest is inactive ingredients — microcrystalline cellulose (a filler), a vegetable capsule, silicon dioxide, and carnauba wax (a coating material).

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: nutrient metabolism support.
  • We looked for evidence on: Biotin deficiency, hair health, nail strength, skin health.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).

Biotin is likely effective for biotin deficiency — the condition it's FDA-reviewed for. For other uses like hair loss (alopecia areata), there isn't enough reliable evidence yet to say whether it works.

For multiple sclerosis and seborrheic dermatitis (a flaky, inflamed scalp condition), the evidence points toward it probably not helping. The data we hold doesn't establish effectiveness for other claims you might see.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at fairly high doses, because your body gets rid of excess in your urine. High-dose biotin has rarely caused mild diarrhea; one study reported temporary loose stools in a couple of patients taking 300 mg daily — far above this 500 mcg dose.

One isolated case report linked very high biotin (10 mg daily) combined with other supplements to a rare lung and heart lining inflammation, but whether biotin was the cause remains unclear, and no similar cases have been reported since. Pregnancy and lactation: the data rates biotin as likely safe during pregnancy and breastfeeding, though the safety notes suggest checking with your doctor before taking high-dose supplements.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for biotin in our data, so there are no specific medication types you need to flag before taking this product. A quick check with your pharmacist is still a good idea if you're on anything new.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product is straightforward: it's a low-dose biotin supplement useful if you have a biotin deficiency. It's well tolerated at this strength.

If you're pregnant, breastfeeding, or taking high-dose biotin for another reason, run that decision past your own doctor or pharmacist first, since the safety data emphasizes caution with higher amounts.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 7, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Biotin 500 mcg, straight from the product label.

Brand The Vitamin Shoppe
Barcode (UPC) 766536019601
Net contents 300 Veggie Capsule(s)
Market status On market
Date entered into DSLD Jan 7, 2019
DSLD ID 184048
Product type Vitamin
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Biotin 500 mcg by The Vitamin Shoppe, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
UPC/BARCODE
766536019601
IngredientAmount% DV
Biotin500 mcg1670%

Other ingredients: Microcrystalline Cellulose, Vegetable capsule, Silicon Dioxide, organic Carnauba Wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Vitamin Nutrient Metabolism

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

FDA Statement of Identity

Dietary Supplement

Formulation

Gluten free Dairy free Soy free Nut free Does not contain: Gluten, Sugar, Salt, Artificial Colors or Flavors.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions: Take one (1) veggie capsule daily, preferably with a meal.

Precautions

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Keep out of reach of children.

Tamper Evident Do not use if outer seal is broken or missing.

Storage

Store in a cool, dry place.

General

Item No. VS-1960 2169118 IS 37

See for yourself

Biotin 500 mcg by The Vitamin Shoppe label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Biotin 500 mcg by The Vitamin Shoppe

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Amounts shown are per serving.

Biotin

No known
interactions
500 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Vegetable capsule, Silicon Dioxide, Organic Carnauba Wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Biotin 500 mcg by The Vitamin Shoppe Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Biotin 500 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Biotin 500 mcg, from the product label.

The Vitamin Shoppe

See all The Vitamin Shoppe products
Name
Vitamin Shoppe, Inc.
City
Secaucus
State
NJ
ZipCode
07094
Phone Number
1-800-223-1216
Web Address
www.vitaminshoppe.com
Pharmacist Counseling Corner

Biotin 500 mcg by The Vitamin Shoppe: Common Questions

Does Biotin 500 mcg by The Vitamin Shoppe interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Biotin 500 mcg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Biotin 500 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my hair grow back?
Biotin is often marketed for hair loss, but the evidence doesn't reliably support it for alopecia areata (patchy hair loss). If you have a confirmed biotin deficiency, correcting it may help — but for general hair thinning or loss, talk to your doctor about what's actually causing it.
Is it safe to take during pregnancy?
Biotin is rated likely safe during pregnancy and lactation. The safety data does suggest checking with your doctor before taking high-dose supplements, so confirm this 500 mcg dose is right for you.
What dose of biotin corrects a deficiency?
The product facts we hold don't specify the dose needed for deficiency — that's individual and depends on how low your level is. Your doctor or a dietitian can advise you on the right amount for your situation.
Can biotin interfere with my medications?
No interactions are documented in our data for biotin. If you want to be thorough, you can search your specific medications on this page or ask your pharmacist.
What's the main thing biotin does?
Biotin is a B vitamin that helps your body break down food and produce energy. It's likely effective if you actually have a biotin deficiency — a condition your doctor would diagnose with a blood test.
Are there any side effects I should watch for?
High-dose biotin has rarely caused mild diarrhea, but this product is a modest 500 mcg dose. At normal dietary and supplement amounts, biotin is very well tolerated.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Biotin 500 mcg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Biotin 500 mcg label
Go deeper

The Full Monographs Behind Biotin 500 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Biotin 500 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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