No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Black Walnut Ingredients & Drug Interactions

by Nature's Sunshine

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Black Walnut is a dietary supplement by Nature's Sunshine with 1 active ingredient. Its ingredients are commonly taken for intestinal parasites and worms, digestive complaints, antimicrobial and antifungal support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Black Walnut by Nature's Sunshine

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Black Walnut hulls extract. The hull is the outer layer of the walnut fruit, and this extract form concentrates what's in that part of the plant.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: intestinal system support.
  • We looked for evidence on: parasitic infection, digestive health, gastrointestinal function.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for Black Walnut hulls extract isn't established yet. Our data shows insufficient reliable evidence to rate it for coronary heart disease or wound healing.

That doesn't mean it doesn't work — it means we don't have enough rigorous studies to say one way or the other.

The evidence, ingredient by ingredient Black Walnut

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Black Walnut hulls extract is generally well tolerated when taken by mouth. The main concern is that the hull contains high amounts of tannins, which can cause stomach upset or gastrointestinal irritation in some people.

Tree nuts, including walnuts, are a major food allergen in the United States, so if you have a tree nut allergy, you should avoid this. The safety data advises against use during pregnancy and breastfeeding — there isn't enough information to know it's safe in those situations.

Short-term use in most healthy adults appears acceptable, but long-term safety hasn't been well studied.

Side effects, ingredient by ingredient Black Walnut

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for Black Walnut hulls extract.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Black Walnut hulls extract may appeal to someone looking for a traditional herbal supplement, but the evidence for what it actually does isn't solid yet. If you have a tree nut allergy, are pregnant, breastfeeding, or have a sensitive stomach, talk to your pharmacist before starting it.

No interactions with medications are documented, but that's always worth a quick double-check with your exact drug list.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Black Walnut, straight from the product label.

Brand Nature's Sunshine
Barcode (UPC) 099904000933
Net contents 50 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 277987
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Black Walnut by Nature's Sunshine, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
50
UPC/BARCODE
099904000933
IngredientAmount% DV
Black Walnut hulls extract480 mg--

Other ingredients: Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Bottle made from 100% post consumer recycled material. We are committed to you and our planet. Scan to learn more.

New look! Same great product

Formula

One capsule contains all the nutritional benefits of four regular black walnut hulls capsules.

Ko Pareve (Kosher)

Seals/Symbols

Ko Pareve (Kosher)

Formulation

Intestinal system support Concentrated

Guaranteed pure

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Natures Sunshine Herbal experts since 1972

Suggested/Recommended/Usage/Directions

Recommended Use: Take 1 capsule with a meal twice daily.

See for yourself

Black Walnut by Nature's Sunshine label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Black Walnut by Nature's Sunshine

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Black Walnut hulls extract

No known
interactions
480 mg per serving

Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these us...

Black Walnut hulls extract monograph & interactions

Other (inactive) ingredients: Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Black Walnut by Nature's Sunshine Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Black Walnut. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Black Walnut, from the product label.

Nature's Sunshine

See all Nature's Sunshine products
Name
Nature's Sunshine Products, Inc.
City
Spanish Fork
State
UT
ZipCode
84660
Phone Number
1-800-223-8225
Web Address
www.naturessunshine.com
Pharmacist Counseling Corner

Black Walnut by Nature's Sunshine: Common Questions

Does Black Walnut by Nature's Sunshine interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Black Walnut. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Black Walnut contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Black Walnut work for heart health?
The evidence isn't there yet. We have insufficient reliable evidence to say whether it helps with coronary heart disease. More research would be needed to know.
Can I take this if I have a tree nut allergy?
No. Black walnuts are tree nuts and are classified as a major food allergen. If you're allergic to tree nuts, you should avoid this product.
What side effects might I have?
The most common is stomach upset or gastrointestinal irritation, thanks to high tannin content in the hull. If you apply it to skin, it may temporarily stain the area yellow or brown and could irritate the skin.
Is it safe to take long-term?
Human safety data are limited, and long-term use hasn't been well studied. Short-term use in healthy adults appears acceptable, but we don't have solid evidence for extended use.
Can I take this while pregnant or breastfeeding?
The safety data advises against use in both pregnancy and breastfeeding — there isn't enough information to know it's safe. Talk with your doctor or pharmacist for personalized advice about your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Black Walnut is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Black Walnut label
Go deeper

The Full Monographs Behind Black Walnut’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Black Walnut's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Walnut 3 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor

See these in context on the Black Walnut monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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