No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Black Walnut Hull Tincture Ingredients & Drug Interactions

by Dr. Clark Research Association Dr. Clark Zentrum

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Black Walnut Hull Tincture is a dietary supplement by Dr. Clark Research Association Dr. Clark Zentrum with 1 active ingredient. Its ingredients are commonly taken for intestinal parasites and worms, digestive complaints, antimicrobial and antifungal support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Black Walnut Hull Tincture by Dr. Clark Research Association Dr. Clark Zentrum

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This tincture contains one active ingredient: black walnut (Juglans nigra) hull. Black walnut has been studied for coronary heart disease and wound healing, though the evidence remains limited.

The product is delivered in a liquid form with distilled water, grain alcohol, green black walnuts, and vitamin C as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Black Walnut product and its label doesn't state a use — see Black Walnut's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for black walnut hull isn't solid yet. Our data shows insufficient reliable evidence to rate it for either coronary heart disease or wound healing.

That doesn't mean it doesn't work — it means the studies so far haven't been strong enough to draw firm conclusions. If you're considering it for a specific health goal, talk it over with your doctor to see whether the current evidence makes sense for your situation.

The evidence, ingredient by ingredient Black Walnut

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Black walnut hull is generally well tolerated in the short term for most adults, but long-term safety hasn't been well studied and human data are limited. The hull contains high tannins, which can trigger gastrointestinal upset when taken by mouth.

Topically, the hull may cause temporary yellow or brown staining and skin irritation. Black walnut is a tree nut and can cause allergic reactions in people with tree nut sensitivity — a major food allergen in the United States.

Daily use of related species (English walnut bark) has been linked to increased tongue cancer and lip leukoplakia risk, so prolonged use warrants caution. During pregnancy, there isn't enough safety information; it's best avoided.

The same applies to breastfeeding.

Side effects, ingredient by ingredient Black Walnut

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, confirm with your own doctor or pharmacist that it's safe to add to your current medications before you begin.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Black Walnut Hull Tincture may appeal to someone exploring traditional herbal remedies, but the evidence for what it actually does is too thin to rely on it as a treatment. If you're pregnant, breastfeeding, or allergic to tree nuts, steer clear.

Talk with your doctor or pharmacist before starting, especially if you plan to use it long-term.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Black Walnut Hull Tincture, straight from the product label.

Brand Dr. Clark Research Association Dr. Clark Zentrum
Barcode (UPC) 7640116922112
Net contents 120 mL; 4 Ounce(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 223432
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Black Walnut Hull Tincture by Dr. Clark Research Association Dr. Clark Zentrum, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Teaspoon(s)
Maximum serving Sizes:
2 Teaspoon(s)
Servings per container
12
UPC/BARCODE
7640116922112
IngredientAmount% DV
Juglans nigra0 NP--

Other ingredients: distilled Water, Grain Alcohol, Green Black Walnuts, Vitamin C

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Extra strong

Made in the USA.

FDA Statement of Identity

Dietary Supplement/Food Supplement

Suggested/Recommended/Usage/Directions

Adults and children 12 or more years of age: 2 tsp in 1/4 cup of water or as directed. After first opening, use within 3 weeks.

Precautions

Store out of reach of young children.

Dietary supplements/food supplements should not be used as a substitute for a varied diet. Do not exceed the stated recommended daily dose.

Contains alcohol.

Storage

Store in the fridge or freezer.

Formula

Contains alcohol.

General Statements

Nominal weight: about 120 g % DV = % Daily Value

See for yourself

Black Walnut Hull Tincture by Dr. Clark Research Association Dr. Clark Zentrum label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Black Walnut Hull Tincture by Dr. Clark Research Association Dr. Clark Zentrum

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Teaspoon(s) Dosage formLiquid Servings per container12 Amounts shown are per serving.

Juglans nigra

No known
interactions
0 NP per serving

Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these us...

Juglans nigra monograph & interactions

Other (inactive) ingredients: Distilled Water, Grain Alcohol, Green Black Walnuts, Vitamin C. These complete the product’s ingredient list but are not active constituents.

Interaction report

Black Walnut Hull Tincture by Dr. Clark Research Association Dr. Clark Zentrum Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Black Walnut Hull Tincture. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Black Walnut Hull Tincture, from the product label.

Dr. Clark Research Association Dr. Clark Zentrum

See all Dr. Clark Research Association Dr. Clark Zentrum products
Name
Dr. Clark Zentrum Limited
Street Address
152 Naxxar Road #7, SGN 9030
City
San Gwann
State
Malta
Web Address
www.drclark.com
Pharmacist Counseling Corner

Black Walnut Hull Tincture by Dr. Clark Research Association Dr. Clark Zentrum: Common Questions

Does Black Walnut Hull Tincture by Dr. Clark Research Association Dr. Clark Zentrum interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Black Walnut Hull Tincture. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Black Walnut Hull Tincture contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will black walnut hull upset my stomach?
The hull contains high amounts of tannins, which can cause gastrointestinal upset when taken by mouth. Most people tolerate it, but if you have a sensitive stomach, this is worth keeping in mind.
Is this safe to take long-term?
The safety data are limited, and long-term use hasn't been well studied. It's considered acceptable for short-term use in most adults, but we don't have solid evidence for safety over months or years. Talk with your doctor if you're thinking of using it regularly.
Can I take this if I'm pregnant or breastfeeding?
No — there isn't enough safety information. Black walnut hull is best avoided during pregnancy and while breastfeeding. Discuss alternatives with your healthcare provider.
Does it work for heart health or wound healing?
The evidence is insufficient right now — we can't say whether it's effective for either. If you're managing a health condition, work with your doctor on treatments with stronger evidence.
Will this stain my skin?
Yes — topically, black walnut hull can cause temporary yellow or brown discoloration at the application site. It may also cause skin irritation.
I'm allergic to tree nuts. Should I avoid this?
Definitely. Black walnut is a tree nut and is classified as a major food allergen. If you have a tree nut allergy, skip this product to avoid a reaction.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Black Walnut Hull Tincture is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Black Walnut Hull Tincture label
Go deeper

The Full Monographs Behind Black Walnut Hull Tincture’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Black Walnut Hull Tincture's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Walnut 3 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor

See these in context on the Black Walnut monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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