No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Caralluma 1000 Ingredients & Drug Interactions

by Optimal Nutrition

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Caralluma 1000 is a dietary supplement by Optimal Nutrition with 1 active ingredient. Its ingredients are commonly taken for appetite suppression, weight management, reducing waist circumference.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Caralluma 1000 by Optimal Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Caralluma 1000 has one active ingredient: caralluma fimbriata (whole plant) extract, a cactus-like plant used traditionally for appetite support. The capsule also contains inactive ingredients—vegetable cellulose, microcrystalline cellulose, magnesium stearate, and silicon dioxide—which are fillers and binders that help deliver the active ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Caralluma's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports weight control and promotes weight loss.
  • We looked for evidence on: Obesity, weight management, appetite suppression, metabolic support.
  • The closest evidence on file: Caralluma is rated "Possibly Ineffective" for Obesity (Natural Medicines).

The evidence for caralluma fimbriata is mixed and limited. For obesity, the data rates it as possibly ineffective—meaning studies haven't shown it works well for weight loss.

For generalized anxiety and Prader-Willi syndrome, there isn't enough reliable evidence to rate it either way. If you're looking at this for appetite or weight, the science doesn't back it up strongly.

The evidence, ingredient by ingredient Caralluma

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Caralluma is generally well tolerated over the short term in studies, but we don't know much about long-term safety. The most common side effects are gastrointestinal—abdominal bloating, constipation, gas, and stomach inflammation—but these usually fade within the first two weeks.

One trial participant with a history of high blood pressure saw a temporary blood pressure spike, though it settled and didn't return. During pregnancy, the safety data advises against it.

While breastfeeding, there isn't enough reliable data; talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Caralluma

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for caralluma fimbriata. That said, check your exact medications using the tool on this page before starting, and let your doctor or pharmacist know you're adding this product.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Caralluma 1000 is generally well tolerated short-term, but the evidence that it works for obesity is weak. If you're pregnant, avoid it; if you're breastfeeding or have high blood pressure concerns, check with your doctor or pharmacist first.

This is a good one to discuss with your own healthcare provider before you start, especially if you're taking other medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Caralluma 1000, straight from the product label.

Brand Optimal Nutrition
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 24, 2015
DSLD ID 44842
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Caralluma 1000 by Optimal Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
IngredientAmount% DV
Caralluma fimbriata (whole plant) extract1000 mg--

Other ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take two (2) capsules per day, with or without food.

Precautions

Warning: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

KEEP OUT OF THE REACH OF CHILDREN.

DO NOT USE IF SAFETY WRAP IS DAMAGED OR MISSING.

Storage

STORE IN A COOL DRY PLACE.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Supports Weight Control Promotes Weight Loss Disrupts Fat Storage

FDA Statement of Identity

Natural Dietary Supplement

General Statements

X000ETRI03

See for yourself

Caralluma 1000 by Optimal Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Caralluma 1000 by Optimal Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

1000 mg per serving

Caralluma fimbriata is an edible succulent plant from India that is marketed mainly as an appetite suppressant and weight-loss aid. Some small studies...

Caralluma fimbriata (whole plant) extract monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Caralluma 1000 by Optimal Nutrition Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Caralluma 1000. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Caralluma 1000, from the product label.

Optimal Nutrition

See all Optimal Nutrition products
Name
Optimal Nutrition LLC
City
Medford
State
OR
ZipCode
97502
Phone Number
888-726-8107
Web Address
www.optimalnutritionllc.com
Pharmacist Counseling Corner

Caralluma 1000 by Optimal Nutrition: Common Questions

Does Caralluma 1000 by Optimal Nutrition interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Caralluma 1000. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Caralluma 1000 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the most common side effects?
Gas, bloating, constipation, and stomach irritation show up in the first couple of weeks for some people. The good news: these usually go away on their own. If they don't, stop and talk to your pharmacist.
Does this actually help with weight loss?
The research doesn't support it strongly. Studies rate caralluma as possibly ineffective for obesity, which means it hasn't shown much promise for weight loss.
Is it safe to take while I'm pregnant?
No. The safety data advises against using caralluma during pregnancy. If you're planning to get pregnant or already are, skip this one and talk to your doctor about alternatives.
Can I use it while breastfeeding?
There isn't enough reliable safety data for breastfeeding. It's best to avoid it unless your doctor or pharmacist says otherwise after reviewing your situation.
How long until the stomach side effects go away?
Most people see them settle within the first two weeks. If they stick around longer or get worse, stop taking it and check in with your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Caralluma 1000 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Caralluma 1000 label
Go deeper

The Full Monographs Behind Caralluma 1000’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Caralluma 1000's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Caralluma 1 reference
  1. Arora E, Khajuria V, Tandon VR, et al. To evaluate efficacy and safety of Caralluma fimbriata in overweight and obese patients: a randomized, single blinded, placebo control trial. Perspect Clin Res 2015;6(1):39-44. PubMed

See these in context on the Caralluma monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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