Colostrum Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Colostrum against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Colostrum is a dietary supplement by California Gold Nutrition with 4 active ingredients. Its ingredients are commonly taken for iron deficiency and anemia support, immune support, gut health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Colostrum by California Gold Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 3 active ingredients sourced from colostrum (the nutrient-rich fluid produced in the first days after birth). Lactoferrin is an iron-binding protein; Immunoglobulins are antibody proteins; and Proline-rich Polypeptides are small protein fragments.
The capsule itself contains modified cellulose and sunflower lecithin as inactive ingredients.
Does it work?
Not established
The evidence here is mixed. Lactoferrin shows possibly effective evidence for sepsis and pregnancy-related iron deficiency, but the data suggests it's likely ineffective for fetal and premature infant mortality and necrotizing enterocolitis (a serious gut condition in premature infants).
We don't hold effectiveness ratings for Immunoglobulins or Proline-rich Polypeptides, so the evidence for those isn't established in our data.
How safe is it?
Well-documented data
Lactoferrin is generally well tolerated at typical doses, but long-term safety data are limited. At very high doses — 7.2 grams daily — it's more likely to cause side effects like constipation, diarrhea, loss of appetite, and fatigue.
In pregnancy and breastfeeding, safety isn't fully established; talk with your doctor or pharmacist if either applies to you. We don't hold safety data on Immunoglobulins or Proline-rich Polypeptides.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
If you're interested in colostrum's components for immune support or iron metabolism, this product is well tolerated at standard doses. Pregnancy and breastfeeding aren't recommended without medical supervision.
Check your medications on this page first, and talk with your pharmacist if you have questions about whether it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Colostrum, straight from the product label.
| Brand | California Gold Nutrition |
|---|---|
| Barcode (UPC) | 898220009138 |
| Net contents | 240 Veggie Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jan 23, 2023 |
| DSLD ID | 273320 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Colostrum by California Gold Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Protein | 1 Gram(s) | -- |
| Lactoferrin | 5 mg | -- |
| Immunoglobulins | 200 mg | -- |
| Proline-rich Polypeptides | 150 mg | -- |
| Colostrum | 1000 mg | -- |
Other ingredients: Modified Cellulose, Sunflower Lecithin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Usage: Take 2 capsules daily, on an empty stomach, with 8 oz of purified water. Best when taken as directed by a qualified healthcare professional.
Formula
Our concentrated, first-milking Colostrum is produced using a proprietary process and is standardized to provide naturally-occurring IgG an PRPs (Proline-Rich-Polypeptides).
20% IgG (Immunoglobulins G1 & G2) 15% PRPs (Proline-Rich Polypeptides) - Considered to be Colostrum's most important fraction.
Non-GMO Lipid Coating
Formulation
Our premium Colostrum is sourced year-round from USDA Grade A dairy cows raised in the United States. It is low-heat processed in a state of the art facility allowing us to provide you with the highest quality Colostrum at an exceptional value!
No rbST Laboratory Confirmed Free of Antibiotics
Aroma, color, consistency and taste may vary.
No rbST (From cows not supplemented with rbST. No significant difference has been shown between milk derived from rbST-supplemented and non-rbST supplemented cows.)
Concentrated May help support Immune Health
Formulated to contain No gluten No GMOs No soy
The standardized Colostrum fraction percentage claims (20% IgG & 15% PRPs) are conservative averages, based on years of analytical results provided by our supplier. These levels may vary slightly from batch to batch, as Colostrum is a naturally-derived ingredient.
This product is not manufactured with eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy or gluten.
Precautions
Warnings: Keep out of reach of children.
Pregnant or lactating women, the chronically ill, elderly, individuals under the age of 18, those taking prescription medications as well as those with a physician-diagnosed medical condition should consult with a physician, pharmacist, naturopath or other qualified healthcare professional prior to taking dietary supplements.
Pregnant or lactating women, the chronically ill, elderly, individuals under the age of 18, those taking prescription medications as well as those with a physician-diagnosed medical condition should consult with a physician, pharmacist, naturopath or other qualified healthcare professional prior to taking dietary supplements.
Sealed for your protection. Do not use if seal is missing or broken.
Contains: Milk
This product is not manufactured with eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy or gluten. Produced in a third-party, audited and registered cGMP compliant facility that may process other products that contain these allergens or ingredients.
Storage
Best stored at controlled room temperature 20 degrees C to 25 degrees C (68 degrees F to 77 degrees F). Improper storage conditions, such as extended exposure to direct sunlight, high heat & humidity can cause product degradation over time.
Brand IP Statement(s)
California Gold Nutrition is a registered trademark of Madre Labs, LLC 2013-2020 California Gold Nutrition
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Colostrum by California Gold Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Colostrum by California Gold Nutrition
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Protein
Colostrum
- › Lactoferrin
- › Immunoglobulins
- › Proline-rich Polypeptides
Other (inactive) ingredients: Modified Cellulose, Sunflower Lecithin. These complete the product’s ingredient list but are not active constituents.
Colostrum by California Gold Nutrition Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Colostrum. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Colostrum, from the product label.
California Gold Nutrition
See all California Gold Nutrition products- Name
- Madre Labs, LLC
- Street Address
- 301 North Lake Avenue, Suite 600
- City
- Pasadena
- State
- CA
- ZipCode
- 91101
- Web Address
- www.calgn.com
Colostrum by California Gold Nutrition: Common Questions
Does Colostrum by California Gold Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant?
Is it safe to use while breastfeeding?
What are the side effects?
Does this actually work for immune support?
Is there any long-term safety data?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Colostrum is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Colostrum’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Colostrum's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lactoferrin 6 references
- Food and Drug Administration, CFSAN/Office of Food Additive Safety. Agency Response Letter GRAS Notice No. GRN 000130. 2003. Available at: http://www.cfsan.fda.gov/~rdb/opa-g130.html (Accessed 29 June 2005).
- Okada S, Tanaka K, Sato T, et al. Dose-response trial of lactoferrin in patients with chronic hepatitis C. Jpn J Cancer Res 2002;93:1063-9. PubMed
- Abu Hashim H, Foda O, Ghayaty E. Lactoferrin or ferrous salts for iron deficiency anemia in pregnancy: A meta-analysis of randomized trials. Eur J Obstet Gynecol Reprod Biol. 2017;219:45-52. PubMed
- Tarnow-Mordi WO, Abdel-Latif ME, Martin A, et al. The effect of lactoferrin supplementation on death or major morbidity in very low birthweight infants (LIFT): a multicentre, double-blind, randomised controlled trial. Lancet Child Adolesc Health. 2020 Jun PubMed
- ELFIN trial investigators group. Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial. Lancet. 2019 Feb 2;393(10170):423-433. doi: 10.1016/S0140-6736(18)32221-9.
- Lepanto MS, Rosa L, Cutone A, Conte MP, Paesano R, Valenti P. Efficacy of lactoferrin oral administration in the treatment of anemia and anemia of inflammation in pregnant and non-pregnant women: An interventional study. Front Immunol. 2018 Sep 21;9:2123. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC