No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Colostrum-IgG Ingredients & Drug Interactions

by Premier Research Labs

Powder Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Colostrum-IgG is a dietary supplement by Premier Research Labs with 2 active ingredients. Its ingredients are commonly taken for immune support, gut health and digestion, exercise recovery.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Colostrum-IgG by Premier Research Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: bovine colostrum, a nutrient-rich fluid produced by cows in the first days after giving birth. It's used as a dietary supplement for its immune and digestive properties.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: immune support and gut health.
  • We looked for evidence on: Exercise-induced respiratory infections, HIV/AIDS-related diarrhea, Influenza, Rotaviral diarrhea, Sepsis, Shigellosis — and 4 related terms.
  • The strongest evidence on file: Bovine Colostrum is rated "Possibly Effective" for HIV/AIDS-related diarrhea (Natural Medicines).
  • Also on file: Bovine Colostrum is rated "Possibly Effective" for Exercise-induced respiratory infections, Rotaviral diarrhea.
  • Also on file: Bovine Colostrum is rated "Possibly Ineffective" for Sepsis.

The evidence for bovine colostrum is mixed. It's rated possibly effective for HIV/AIDS-related diarrhea, rotaviral diarrhea, and exercise-induced respiratory infections.

For necrotizing enterocolitis (NEC), a serious intestinal condition in newborns, it's rated possibly ineffective. The data we hold doesn't establish its effectiveness for other uses.

The evidence, ingredient by ingredient Bovine Colostrum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bovine colostrum is generally well tolerated in most adults. However, if you have a milk or dairy allergy, you should avoid it.

A small number of trial participants reported mild bloating, nausea, diarrhea, and unsettled stomach at rates similar to those taking a whey-based control. In individuals with HIV-related diarrhea, there have been reports of nausea and vomiting, elevated liver function tests, and decreased blood cell counts — so extra caution is warranted if you're in that situation.

Safety data during pregnancy isn't reliable enough to recommend it, and there isn't enough information to know whether it's safe during breastfeeding — talk with your doctor or pharmacist before using it in either case.

Side effects, ingredient by ingredient Bovine Colostrum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for bovine colostrum. Still, check your exact medications with the tool on this page before you start, and let your doctor or pharmacist know you're considering it.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Bovine colostrum may help with certain types of infectious diarrhea and exercise-related infections, though the evidence is still developing. It's generally well tolerated, but steer clear if you have a dairy allergy, and check with your doctor or pharmacist before you take it — especially if you're pregnant, breastfeeding, or managing HIV-related illness.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Colostrum-IgG, straight from the product label.

Brand Premier Research Labs
Barcode (UPC) 807735027605
Net contents 5 Ounce(s); 150 Gram(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 268935
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Colostrum-IgG by Premier Research Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.2 Gram(s)
Maximum serving Sizes:
1.2 Gram(s)
Servings per container
125
UPC/BARCODE
807735027605
IngredientAmount% DV
Protein1 Gram(s)2%
Bovine Colostrum1.2 Gram(s)--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 teaspoon, 2 times daily mixed in food or drinks or as directed by a health professional.

Storage

Please refrigerate after opening.

Store in a cool, dry place.

Formula

Pesticide-tested, premier quality bovine colostrum with immunoglobulins for effective immune support

Colostrum is a special fluid secreted by a cow for about 3 days after giving birth.

Colostrum-IgG with immunoglobulins

Natural immunoglobulins

Precautions

Tamper seal: Use only if inner seal is intact.

Consult your health care practitioner if you are pregnant/nursing, taking medications or have a medical condition, before taking this or any other product.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Premier immune and stamina support

PRL's quality guarantee Purity verified Forensic test for adulterants No chemical or radiation sterilization Pathogen microbiology performed Pesticide tested Heavy metal tested FDA-monitored cGMP facility

PRL's quality program. Manufactured to avoid: added magnesium stearate (an undesirable excipient), artificial colors, artificial flavors or artificial preservatives.

Manufactured in a cGMP compliant facility for superior quality assurance

FDA Statement of Identity

Dietary Supplement

General Statements

Premier quality you can count on for a lifetime

See for yourself

Colostrum-IgG by Premier Research Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Colostrum-IgG by Premier Research Labs

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1.2 Gram(s) Dosage formPowder Servings per container125 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

1 Gram(s) per serving

Bovine Colostrum

No known
interactions
1.2 Gram(s) per serving Form: Milk

Bovine colostrum is the nutrient-rich first milk from cows, packed with antibodies, growth factors, and protein. Early research suggests it may help w...

Bovine Colostrum monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Colostrum-IgG by Premier Research Labs Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Colostrum-IgG. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Colostrum-IgG, from the product label.

Premier Research Labs

See all Premier Research Labs products
Name
Premier Research Labs
Pharmacist Counseling Corner

Colostrum-IgG by Premier Research Labs: Common Questions

Does Colostrum-IgG by Premier Research Labs interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Colostrum-IgG. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Colostrum-IgG contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have a dairy allergy?
No — bovine colostrum comes from cow's milk, and those with a milk or dairy allergy should avoid it. If you're unsure whether you have a dairy allergy or sensitivity, talk with your doctor or pharmacist first.
What side effects might I experience?
A small number of trial participants reported mild bloating, nausea, diarrhea, and unsettled stomach at rates similar to those taking a comparison product. In people with HIV and infectious diarrhea, there have been isolated reports of nausea, vomiting, elevated liver function tests, and low blood cell counts — so talk with your doctor if you're in that group.
Is this safe during pregnancy or breastfeeding?
There isn't enough reliable safety data for either pregnancy or breastfeeding. Talk with your doctor or pharmacist before taking it in either case — they can weigh the benefits and risks for your situation.
Will this help my diarrhea?
Bovine colostrum is possibly effective for HIV/AIDS-related diarrhea and rotaviral diarrhea. If you have other types of diarrhea, the evidence we hold doesn't establish whether it will help — ask your doctor or pharmacist whether it's a good fit for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Colostrum-IgG is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Colostrum-IgG label
Go deeper

The Full Monographs Behind Colostrum-IgG’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Colostrum-IgG's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bovine Colostrum 8 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Greenberg PD, Cello JP. Treatment of severe diarrhea caused by Cryptosporidium parvum with oral bovine immunoglobulin concentrate in patients with AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 1996;13:348-54. PubMed
  3. Duff WR, Chilibeck PD, Rooke JJ, Kaviani M, Krentz JR, Haines DM. The effect of bovine colostrum supplementation in older adults during resistance training. Int J Sport Nutr Exerc Metab. 2014 Jun;24(3):276-85. PubMed
  4. Sanctuary MR, Kain JN, Chen SY, et al. Pilot study of probiotic/colostrum supplementation on gut function in children with autism and gastrointestinal symptoms. PLoS One. 2019;14(1):e0210064. PubMed
  5. Porcaro F, Caminiti L, Crisafulli G, Guglielmo F, Pajno GB. Anaphylaxis to cutaneous exposure to bovine colostrum based cream. Asian Pac J Allergy Immunol. 2019;37(1):9-11.
  6. Yan X, Pan X, Ding L, et al. Bovine colostrum to supplement the first feeding of very preterm infants: The PreColos randomized controlled trial. Clin Nutr 2023;42(8):1408-1417. PubMed
  7. Halasa M, Skonieczna-Zydecka K, Machalinski B, Bühner L, Baskiewicz-Halasa M. Six Weeks of Supplementation with Bovine Colostrum Effectively Reduces URTIs Symptoms Frequency and Gravity for Up to 20 Weeks in Pre-School Children. Nutrients 2023;15(16):3626 PubMed
  8. Simonsen MB, Kappel SS, Aunsholt L, Möller S, Sangild PT, Zachariassen G. Mineral supplementation for very preterm infants fed fortified human milk. J Pediatr Gastroenterol Nutr 2024;78(6):1389-1397. PubMed

See these in context on the Bovine Colostrum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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