No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

D-Glucuronolactone Ingredients & Drug Interactions

by BulkSupplements.com

D-Glucuronolactone label
See full label image
Powder Category: Non-nutrient/non-botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking D-Glucuronolactone against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

D-Glucuronolactone is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for energy and stamina, mental focus and alertness, reducing fatigue.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of D-Glucuronolactone by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: D-glucuronolactone, a compound your body naturally produces and uses in detoxification processes. It's commonly found in energy drinks and pre-workout supplements.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Glucuronolactone product and its label doesn't state a use — see Glucuronolactone's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness data for D-glucuronolactone in our monograph. The evidence supporting its benefits isn't established in the information we have on file.

The evidence, ingredient by ingredient Glucuronolactone

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

D-glucuronolactone is generally well tolerated in the amounts typically found in beverages, but long-term safety and what happens at higher doses haven't been well studied. There's not enough safety data to recommend it during breastfeeding — avoidance is the safer choice during that time.

We also hold no reliable safety information for pregnancy, so talk with your doctor or pharmacist if you're pregnant or planning to be before using this product.

Side effects, ingredient by ingredient Glucuronolactone

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for D-glucuronolactone with any medication categories. That doesn't mean none exist — just that they haven't been formally identified in our records.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.

D-glucuronolactone is a naturally occurring compound with no documented medication interactions, so it's not a red flag from a drug-interaction standpoint. However, long-term and high-dose safety hasn't been established, and it's often paired with caffeine in supplements — something to keep in mind.

If you're pregnant, breastfeeding, or taking regular medications, check with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D-Glucuronolactone, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X000Y6TYUD
Net contents 1 Kilogram(s); 35.3 Ounce(s)
Market status On market
Date entered into DSLD Sep 25, 2023
DSLD ID 294983
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D-Glucuronolactone by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1000 mg
Maximum serving Sizes:
1000 mg
Servings per container
1000
UPC/BARCODE
X000Y6TYUD
IngredientAmount% DV
D-Glucuronolactone1000 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

BulkSupplements.com Clean & Pure Bulk Supplements

Formulation

Free of: Added sugar, soy, dairy, yeast, gluten, additives

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1000 mg (about 1/3 tsp) one to three times daily, or as directed by a physician.

Storage

Store in a dry, cool place

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

General Statements

New

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

D-Glucuronolactone by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

D-Glucuronolactone label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in D-Glucuronolactone by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1000 mg Dosage formPowder Servings per container1000 Amounts shown are per serving.

D-Glucuronolactone

No known
interactions
1000 mg per serving

Glucuronolactone is a naturally occurring compound that is commonly added to energy drinks and supplements, often alongside caffeine and taurine. Ther...

D-Glucuronolactone monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

D-Glucuronolactone by BulkSupplements.com Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in D-Glucuronolactone. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for D-Glucuronolactone, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

D-Glucuronolactone by BulkSupplements.com: Common Questions

Does D-Glucuronolactone by BulkSupplements.com interact with any medications?
We do not currently list a known interaction for the mapped ingredients in D-Glucuronolactone. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
D-Glucuronolactone contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is D-glucuronolactone safe long-term?
Long-term safety and the effects of high doses haven't been well studied, so we don't have solid data on how it holds up over time. If you're thinking of taking it regularly, talk with your doctor or pharmacist about whether it's right for you.
Can I take this while breastfeeding?
There's not enough safety data for D-glucuronolactone during breastfeeding, so avoidance is the safer choice. If breastfeeding and want to consider a supplement, check with your doctor or pharmacist first.
Is it safe to take during pregnancy?
We don't have reliable safety information for pregnancy. Talk with your doctor or pharmacist about whether this product is appropriate for you if you're pregnant or planning to be.
What does D-glucuronolactone actually do?
It's a compound your body naturally makes and uses in detoxification. We don't have established evidence on file about what benefits supplementing with extra amounts provides.
Why is this often combined with caffeine?
D-glucuronolactone is a common ingredient in energy drinks and pre-workout formulas, where it's usually paired with caffeine. That combination hasn't been fully safety-tested, so if you're using this powder and adding caffeine on top, be mindful of your total intake.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D-Glucuronolactone is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D-Glucuronolactone label
Go deeper

The Full Monographs Behind D-Glucuronolactone’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glucuronolactone

Glucuronolactone is a naturally occurring compound that is commonly added to energy drinks and supplements, often alongside caffeine and taurine. There is very little solid human evidence th...

Read the full Glucuronolactone monograph →
Sources

Sources & How We Checked

D-Glucuronolactone's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glucuronolactone 2 references
  1. Caffeine and Energy Drinks — NIH National Center for Complementary and Integrative Health Source
  2. Caffeine — MedlinePlus Source

See these in context on the Glucuronolactone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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