Major interaction on record — check this product against your medications before combining. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

D3 125 mcg + K2 100 mcg Ingredients & Drug Interactions

by Sports Research

D3 125 mcg + K2 100 mcg label
See full label image
Softgel Capsule Category: Vitamin
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking D3 125 mcg + K2 100 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

D3 125 mcg + K2 100 mcg is a dietary supplement by Sports Research with 2 active ingredients. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against D3 125 mcg + K2 100 mcg by Sports Research

Ask about any prescription or over-the-counter medication and we check it for interactions with D3 125 mcg + K2 100 mcg by Sports Research — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of D3 125 mcg + K2 100 mcg by Sports Research

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains 2 active ingredients: vitamin D3 (125 mcg) and vitamin K2 (100 mcg). Both are fat-soluble vitamins that support bone and cardiovascular health.

The softgel also contains several inactive ingredients — coconut oil, modified tapioca starch, glycerin, purified water, turmeric, and olive oil — that help deliver and preserve the active compounds.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Vitamin D and K2 nutritional support.
  • We looked for evidence on: Hemorrhagic disease, Hypoprothrombinemia, Vitamin K-dependent clotting factors deficiency (VKCFD), Warfarin anticoagulation, Osteoporosis, Cardiovascular disease (CVD) — and 3 related terms.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Hemorrhagic disease (Natural Medicines).
  • Also on file: Vitamin K is rated "Effective" for Hypoprothrombinemia, Warfarin anticoagulation, Vitamin K-dependent clotting factors deficiency (VKCFD).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.

Vitamin K2 is effective for treating vitamin K deficiency conditions and managing warfarin therapy. It's also possibly effective for osteoporosis.

The effectiveness data we hold doesn't cover vitamin D3 for this product, and we have no data on VEGADELIGHT, so we can't speak to their established benefits from our records.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin K2 taken by mouth is generally well tolerated. The most common mild side effects are nausea, diarrhea, abdominal pain, and stomach upset.

Vitamin K2 is rated likely safe in pregnancy and lactation. We don't hold safety data on VEGADELIGHT.

As always, if you're pregnant, breastfeeding, or have a health condition, check with your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take warfarin (Coumadin) or any blood thinner (anticoagulant) — vitamin K2 is a Major interaction and can reduce their effectiveness. We could not check the second ingredient, VEGADELIGHT, so if it has any interactions, we don't have that data on file.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

If you're on warfarin or another blood thinner, do not start this product without talking to your doctor or pharmacist first — the vitamin K2 can interfere with how your medication works. For others looking to support bone and cardiovascular health, this combination may be worth considering, but run it by your healthcare provider so they can factor in your full picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D3 125 mcg + K2 100 mcg, straight from the product label.

Brand Sports Research
Barcode (UPC) 023249011347
Net contents 60 Veggie Softgel(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 309609
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D3 125 mcg + K2 100 mcg by Sports Research, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Softgel(s)
Maximum serving Sizes:
1 Veggie Softgel(s)
Servings per container
60
UPC/BARCODE
023249011347
IngredientAmount% DV
Vitamin K2100 mcg--
VEGADELIGHT125 mcg625%

Other ingredients: Coconut, Tapioca Starch, Modified, Glycerin, Water, Purified, Turmeric, Olive Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Adults take 1 veggie softgel daily with food, or as recommended by a qualified healthcare professional.

This product is intended for individuals who do not obtain the RDI through their daily diet.

Formulation

Quality matters Third party tested cGMP compliant

Non GMO Project Verified nongmoproject.org Non-GMO Verified Gluten-free

Certified Vegan Vegan.org

Plant-based Supports bone & immune health

Vegan

Proudly manufactured in the USA with carefully selected ingredients of domestic and international origins. Lot number & best by date printed on bottom of bottle.

Seals/Symbols

Non GMO Project Verified nongmoproject.org Certified Vegan Vegan.org

Precautions

Caution: Keep out of reach of children and pets.

Do not consume with other high dose Vitamin D supplements. Do not exceed recommended daily intake. Do not use if safety seal is damaged or missing.

Consult with a qualified healthcare professional prior to using this product especially if you are pregnant, nursing, have a diagnosed medical condition, or are taking a prescription medication (e.g., anticoagulants [coumadin/warfarin[).

Contains: Tree nuts (coconut).

Storage

Store at room temperature, in a dry place. Protect from excessive heat, freezing, humidity and light.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

HDPE Non BPA Please recycle Scan for more

@sportsresearch

Formula

125mcg (5000 IU) D3 100mcg K2 D3 + K2 with coconut MCT

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Vegadelight is a registered trademark of Nutraland USA, Inc.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

D3 125 mcg + K2 100 mcg by Sports Research label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

D3 125 mcg + K2 100 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in D3 125 mcg + K2 100 mcg by Sports Research

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Veggie Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin K2

Interacts with
2 drugs
100 mcg per serving Form: Menaquinone-7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

VEGADELIGHT

125 mcg per serving Form: Vitamin D

Other (inactive) ingredients: Coconut, Tapioca Starch, Modified, Glycerin, Water, Purified, Turmeric, Olive Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

D3 125 mcg + K2 100 mcg by Sports Research Drug Interactions

Want to check YOUR meds against D3 125 mcg + K2 100 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Vitamin K2 2

Individual Drug Interactions

The ingredients in D3 125 mcg + K2 100 mcg interact with 2 drugs. Click any drug to see the details.

1 of the 2 ingredients in D3 125 mcg + K2 100 mcg interact with drugs. Each result below shows which ingredient is responsible. Vitamin K2

Each ingredient & the kinds of drugs it affects

For each ingredient in D3 125 mcg + K2 100 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
Vitamin K2 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for D3 125 mcg + K2 100 mcg, from the product label.

Sports Research

See all Sports Research products
Name
Sports Research
Street Address
784 Channel St.
City
San Pedro
State
CA
ZipCode
90731
Phone Number
(310) 519-1484
Web Address
sportsresearch.com
Pharmacist Counseling Corner

D3 125 mcg + K2 100 mcg by Sports Research: Common Questions

Does D3 125 mcg + K2 100 mcg by Sports Research interact with any medications?
Yes. Based on its ingredients, D3 125 mcg + K2 100 mcg has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
D3 125 mcg + K2 100 mcg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this interfere with my warfarin?
Yes — vitamin K2 can antagonize warfarin and reduce its blood-thinning effect. If you take warfarin, you must check with your doctor or pharmacist before starting this product. They may need to adjust your dose or monitor you more closely.
What's VEGADELIGHT, and why couldn't you check it?
We don't hold interaction data for VEGADELIGHT, so we can't tell you what it interacts with. Your pharmacist or doctor may be able to look it up or advise you on whether it's safe with your medications.
Are there any common side effects from the vitamin K2?
Vitamin K2 taken by mouth is generally well tolerated. The most common mild side effects are nausea, diarrhea, abdominal pain, and stomach upset — though most people don't experience them.
Is this safe during pregnancy?
Vitamin K2 is rated likely safe in pregnancy. We don't have safety data on file for VEGADELIGHT, so talk with your doctor or pharmacist about the full product if you're pregnant or breastfeeding.
Does this actually work for bone health?
Vitamin K2 is possibly effective for osteoporosis. We don't have effectiveness data on file for vitamin D3 or VEGADELIGHT in this product, so ask your doctor whether the combination is right for your needs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D3 125 mcg + K2 100 mcg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D3 125 mcg + K2 100 mcg label
Go deeper

The Full Monographs Behind D3 125 mcg + K2 100 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph →
Sources

Sources & How We Checked

D3 125 mcg + K2 100 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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