Daily Enzyme Complex By Bronson Overview & Drug Interactions

Niacin, also known as vitamin B3, is a water-soluble vitamin found in a variety of foods, including meat, poultry, fish, and fortified grains. It plays a variety of roles in the body, including in the metabolism of carbohydrates, fats, and proteins. It is also necessary for the production of energy in the body and in the synthesis of different hormones. Niacin deficiency is rare in developed countries, however, supplementation has been shown to have several positive benefits. For example, it can reduce the risk of diabetic neuropathy (i.e., nerve pain) and has been shown effective for treating some types of high cholesterol (extended-release niacin is used as a prescription drug in the United States for this purpose). There is a multitude of niacin forms available as dietary supplements, including NADH, niacinamide, and nicotinamide riboside, all with different properties.

Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.

Papaya, scientifically known as Carica papaya, is a tropical fruit celebrated for its vibrant orange flesh, sweet flavor, and numerous health benefits. Originating in Central America, papaya is now cultivated in tropical and subtropical regions worldwide. Rich in vitamins A and C, as well as enzymes like papain, papaya is recognized for its digestive and immune-boosting properties. Its versatile use ranges from consumption as a fresh fruit to the production of dietary supplements, skincare products, and even meat tenderizers due to its enzymatic content.

Bromelain is a group of proteolytic enzymes derived from pineapples. It has been traditionally used for its anti-inflammatory and protein-digesting properties. Some research suggests it may have potential benefits for conditions such as allergic rhinitis, burns, cancer, diabetic foot ulcers, and postoperative pain, among others. However, the evidence for its effectiveness in these areas is lacking, and more research is needed. It is important to note that bromelain should not be confused with other protein-digesting enzymes. Pregnant and lactating individuals should avoid using bromelain due to insufficient information about its safety in these populations.

Anise, also known as Pimpinella anisum, is an herb native to the eastern Mediterranean region and Southwest Asia. The seeds are known for their mildly sweet, licorice-like flavor. The main compound in anise responsible for the licorice-like taste and odor is anethole. Anise seeds are often used in baking and liquors. It is especially popular during the winter holiday season. It has a long history of use in traditional medicine and has been used to treat a variety of conditions, including digestive problems, respiratory disorders, and insomnia. Anise is also used as a natural remedy for cough, sore throat, and other respiratory problems.

Peppermint is a perennial herb that is native to Europe and Asia. It is a member of the mint family (Lamiaceae) and is known for its fragrant, minty aroma and distinctive, spear-shaped leaves. Peppermint is commonly used in cooking and aromatherapy, as well as in a variety of personal care products. It has a refreshing, cool, and slightly sweet flavor. In traditional medicine, peppermint is believed to have a number of health benefits. It is thought to have anti-inflammatory and pain-relieving effects, and it is sometimes used to treat a variety of conditions, including digestive problems, respiratory infections, and skin disorders. Peppermint is also commonly used as a natural treatment for colds and flu due to its expectorant properties. Some peppermint supplements are marketed specifically towards those suffering from IBS (irritable bowel syndrome) as evidence shows it can help reduce symptoms in some individuals.

Bacillus coagulans, also known as Weizmannia coagulans or Lactobacillus sporogenes, is a spore-forming, lactic acid-producing, Gram-positive bacterium used as a probiotic. Bacillus coagulans has shown benefits for constipation and irritable bowel syndrome (IBS). Its spores are stable in stomach acid and reach the small intestine, where they germinate and multiply, with around 85% reaching their destination. The bacterium is excreted via feces, with spores detectable up to 7 days post-administration. Mechanistically, Bacillus coagulans exhibits antibacterial effects through the production of coagulin, lactic acid, and lactosporin, reducing pathogenic bacteria colonization. It also demonstrates antifungal properties and anti-inflammatory effects, potentially reducing the growth of pathogenic bacteria and decreasing the production of lipopolysaccharides. Bacillus coagulans may stimulate immune response, as evidenced by increased CD4+ T cells in adults with HIV-1 infection and modulation of inflammatory cytokines in schoolchildren. These properties categorize Bacillus coagulans as an immunomodulator, immunostimulant, and probiotic, with potential therapeutic applications in promoting digestive health and immune function.