Daily Essential Enzymes 500 mg Ingredients & Drug Interactions
by Source Naturals
What is this page for?
First and foremost: checking Daily Essential Enzymes 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Daily Essential Enzymes 500 mg is a dietary supplement by Source Naturals with 8 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Daily Essential Enzymes 500 mg by Source Naturals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Daily Essential Enzymes contains eight active enzyme ingredients in a 500 mg capsule: Lipase, Lactase, Cellulase, Hemicellulase, acid-stable Protease, Amyloglucosidase, Alpha-Amylase, and Vegetal Analog of Pancreatin. These are digestive enzymes that work to break down different components of food — fats, lactose, plant fiber, proteins, and carbohydrates — to support nutrient absorption.
The capsule itself is filled with inactive ingredients including gelatin, calcium sulfate, stearic acid, silica, and magnesium stearate.
Does it work?
Strong evidence
Lactase in this product is rated effective for lactose intolerance. The other active ingredients — Lipase for inflammatory bowel disease and indigestion, and acid-stable Protease — don't have enough reliable evidence for us to say whether they work for their intended purposes.
We don't hold effectiveness data for Cellulase, Hemicellulase, Amyloglucosidase, Alpha-Amylase, or Vegetal Analog of Pancreatin.
How safe is it?
Well-documented data
Lipase is generally well tolerated in supplement form, but people with serious digestive conditions should use it only under medical guidance. There's little safety data on supplemental lipase in pregnancy or during breastfeeding, so check with your doctor first if either applies to you.
Lactase is generally well tolerated; it's rated likely safe in pregnancy but check with your doctor about regular use. Acid-stable Protease may cause digestive upset or allergic reactions in some people, and safety hasn't been established in pregnancy, so it's best avoided then unless prescribed.
Little data exists for this protease during breastfeeding. Rare cases of allergic reactions to proteolytic enzymes (contact dermatitis, allergic rhinoconjunctivitis, asthma) have been reported, usually from occupational airborne or skin exposure.
Meds to double-check
No known interactions
No interactions are documented in our data for the enzymes we could check. That said, we don't hold interaction information for Cellulase, Hemicellulase, Amyloglucosidase, Alpha-Amylase, or Vegetal Analog of Pancreatin, so check your specific medication list with your pharmacist or doctor before starting.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This product is mainly useful if you have lactose intolerance — that's the one enzyme with solid evidence behind it. If you have serious digestive problems, work with your doctor before using it.
Pregnant or breastfeeding individuals should talk with their doctor or pharmacist first, since safety data are limited for most of the enzymes here. Run your medications through the checker on this page to be sure.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Daily Essential Enzymes 500 mg, straight from the product label.
| Brand | Source Naturals |
|---|---|
| Barcode (UPC) | 021078006596 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2023 |
| DSLD ID | 295692 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Daily Essential Enzymes 500 mg by Source Naturals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lipase | 125 mg | -- |
| Lactase | 5 mg | -- |
| Cellulase | 5 mg | -- |
| Hemicellulase | 3 mg | -- |
| acid-stable Protease | 12 mg | -- |
| Amyloglucosidase | 12 mg | -- |
| Alpha-Amylase | 52 mg | -- |
| Vegetal Analog of Pancreatin | 286 mg | -- |
Other ingredients: Gelatin, Calcium Sulfate Anhydrous, Stearic Acid, Silica, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Each capsule contains 500 mg of an all-vegetarian, broad spectrum blend of digestive enzymes.
Suggested/Recommended/Usage/Directions
Directions: 1 capsule with water at the beginning of each meal (or open capsule and sprinkle over food). If the meal is very large or unusually high in fat or protein, a second capsule can be taken. Do not sprinkle on hot food.
Storage
Store in a cool, dry place.
Precautions
Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.
Do not use if either tamper-evident seal is broken or missing.
Keep out of the reach of children.
Formulation
Hypoallergenic: Contains no yeast, dairy, egg, gluten, corn, soy or wheat.
Hypoallergenic: Contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.
Bio Align
Digestive aid
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
Copyright Source Naturals, INC.
FDA Statement of Identity
Enzyme Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Daily Essential Enzymes 500 mg by Source Naturals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Daily Essential Enzymes 500 mg by Source Naturals
These are the 8 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Lipase
No knowninteractions
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...
Lipase monograph & interactionsLactase
No knowninteractions
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...
Lactase monograph & interactionsCellulase
Hemicellulase
Acid-stable Protease
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Acid-stable Protease monograph & interactionsAmyloglucosidase
Alpha-Amylase
Vegetal Analog of Pancreatin
Other (inactive) ingredients: Gelatin, Calcium Sulfate Anhydrous, Stearic Acid, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Daily Essential Enzymes 500 mg by Source Naturals Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Daily Essential Enzymes 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Daily Essential Enzymes 500 mg, from the product label.
Source Naturals
- Name
- Source Naturals, Inc.
- Street Address
- P. O. Box 2118
- City
- Santa Cruz
- State
- CA
- ZipCode
- 95062
- Web Address
- www.sourcenaturals.com
Daily Essential Enzymes 500 mg by Source Naturals: Common Questions
Does Daily Essential Enzymes 500 mg by Source Naturals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does Lactase in this product really help with lactose intolerance?
Can I take this while pregnant?
Is it safe to breastfeed while using this?
What are these enzymes actually for?
Are there any side effects?
Can this help inflammatory bowel disease or indigestion?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Daily Essential Enzymes 500 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Daily Essential Enzymes 500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
Daily Essential Enzymes 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC