No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 8 ingredients. Check your meds →
Dietary supplement

Daily Essential Enzymes 500 mg Ingredients & Drug Interactions

by Source Naturals

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Daily Essential Enzymes 500 mg is a dietary supplement by Source Naturals with 8 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Daily Essential Enzymes 500 mg by Source Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 8 of its 8 active ingredients.
  • “To Break Down Protein” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “To Break Down Fats” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “To Break Down Carbohydrates” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Daily Essential Enzymes contains eight active ingredients designed to support your digestion. Lactase breaks down milk sugar (lactose), lipase helps digest fats, and acid-stable protease breaks down protein.

The product also includes cellulase, hemicellulase, alpha-amylase, vegetal analog of pancreatin, and amyloglucosides to help break down fiber and carbohydrates. The capsules are filled with inactive ingredients including gelatin, calcium sulfate, stearic acid, silica, and magnesium stearate.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: digestive aid enzyme supplement.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, indigestion, gas and bloating.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Lactase in this product is rated effective for lactose intolerance — it helps your body digest milk sugar if you're lactose intolerant. For the other ingredients, the evidence isn't established in the data we hold.

Lipase and acid-stable protease are listed for dyspepsia (indigestion) and inflammatory bowel disease, but the data shows insufficient reliable evidence to rate how well they actually work for those uses.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase Lactase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated when used as directed. Lipase and acid-stable protease are also generally well tolerated in supplement form, though people with serious digestive conditions should use them only under medical guidance.

Rare allergic reactions to protease have been reported in occupational settings. Lactase-induced contact dermatitis and allergic rhinoconjunctivitis have been reported in workers exposed to powdered lactase, though this is uncommon.

For pregnancy, lactase is rated likely safe, but lipase and acid-stable protease have limited safety data — check with your doctor before using during pregnancy or breastfeeding.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase Lactase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. However, we could not check cellulase, hemicellulase, alpha-amylase, vegetal analog of pancreatin, or amyloglucosides, so ask your pharmacist if you take any regular medications.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product is for anyone looking to support digestion, especially if you're lactose intolerant. If you have a serious digestive condition, take it only under your doctor's guidance.

Since we couldn't check all the ingredient interactions, run your medications through our tool on this page before starting, and talk it over with your own doctor or pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Daily Essential Enzymes 500 mg, straight from the product label.

Brand Source Naturals
Barcode (UPC) 021078009696
Net contents 240 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2023
DSLD ID 295696
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Daily Essential Enzymes 500 mg by Source Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
240
UPC/BARCODE
021078009696
IngredientAmount% DV
Lactase5 mg--
Lipase125 mg--
Cellulase5 mg--
Hemicellulase3 mg--
acid-stable Protease12 mg--
Alpha-Amylase52 mg--
Vegetal Analog of Pancreatin286 mg--
To Break Down Protein0 NP--
To Break Down Fats0 NP--
To Break Down Carbohydrates0 NP--
To Break Down Fiber0 NP--
To Break Down Milk Sugar0 NP--
Amyloglucosides12 mg--

Other ingredients: Gelatin, Calcium Sulfate, Anhydrous, Stearic Acid, Silica, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Bio Align

Digestive aid

Each capsule contains 500 mg of an all-vegetarian, broad spectrum blend of digestive enzymes.

Hypoallergenic: contains no yeast, dairy, egg, gluten, corn, soy or wheat.

Hypoallergenic: contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

FCC (Food Chemical Codex) units measure enzyme activity.

FDA Statement of Identity

Enzyme Supplement

Formula

Each capsule contains 500 mg of an all-vegetarian, broad spectrum blend of digestive enzymes.

Suggested/Recommended/Usage/Directions

Directions: 1 capsule with water at the beginning of each meal (or open capsule and sprinkle over food). If the meal is very large or unusually high in fat or protein, a second capsule can be taken. Do not sprinkle on hot food.

Storage

Store in a cool, dry place.

Precautions

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Copyright Source Naturals, Inc.

See for yourself

Daily Essential Enzymes 500 mg by Source Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Daily Essential Enzymes 500 mg by Source Naturals

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container240 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

To Break Down Protein

0 NP per serving

To Break Down Fats

0 NP per serving

To Break Down Carbohydrates

0 NP per serving
  • › Alpha-Amylase
  • › Amyloglucosides

To Break Down Fiber

0 NP per serving
  • › Cellulase
  • › Hemicellulase

To Break Down Milk Sugar

0 NP per serving

Other (inactive) ingredients: Gelatin, Calcium Sulfate, Anhydrous, Stearic Acid, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Daily Essential Enzymes 500 mg by Source Naturals Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Daily Essential Enzymes 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Daily Essential Enzymes 500 mg, from the product label.

Source Naturals

Name
Source Naturals, Inc.
Street Address
P. O. Box 2118
City
Santa Cruz
State
CA
ZipCode
95062
Web Address
www.sourcenaturals.com
Pharmacist Counseling Corner

Daily Essential Enzymes 500 mg by Source Naturals: Common Questions

Does Daily Essential Enzymes 500 mg by Source Naturals interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Daily Essential Enzymes 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Daily Essential Enzymes 500 mg contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this product safe during pregnancy?
Lactase is rated likely safe in pregnancy. Lipase and acid-stable protease have limited safety data — the facts advise against acid-stable protease during pregnancy unless prescribed, and recommend checking with your doctor before using lipase. Talk to your own doctor or pharmacist about whether this product is right for you during pregnancy.
Does lactase really help with lactose intolerance?
Yes — lactase is rated effective for lactose intolerance. It breaks down milk sugar, which is what your body struggles to do if you're lactose intolerant.
Can this cause allergic reactions?
Allergic reactions are rare. A case of allergic rhinoconjunctivitis and contact dermatitis from lactase exposure in a worker has been reported. Protease-specific allergic reactions have also been reported, mostly in occupational settings with high exposure. Most people tolerate these enzymes well.
Is this safe if I have digestive problems like IBD?
People with serious digestive conditions should use lipase and these enzymes only under medical guidance. Check with your doctor before starting, especially if you have inflammatory bowel disease or another chronic digestive issue.
Does this product have fillers?
Yes — the capsules contain inactive ingredients including gelatin, calcium sulfate, stearic acid, silica, and magnesium stearate.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Daily Essential Enzymes 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Daily Essential Enzymes 500 mg label
Sources

Sources & How We Checked

Daily Essential Enzymes 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring