Digestazyme Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Digestazyme against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Digestazyme is a dietary supplement by Akasha Naturals with 11 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Digestazyme by Akasha Naturals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Digestazyme contains 11 active digestive enzymes. Lipase breaks down fats; lactase helps digest milk sugar (lactose); and the proteases (acid protease, neutral protease, and fungal protease) break down proteins.
You also get cellulase, invertase, xylanase, pectinase, hemicellulase, and amylase—each one targets different food components to aid breakdown during digestion. The capsule itself is made from inactive ingredients including hydroxypropyl methylcellulose, maltodextrin, and medium chain triglyceride.
Does it work?
Strong evidence
Lactase in this product is effective for lactose intolerance. For the other enzymes—lipase, the proteases, and the carbohydrate-digesting ones—the evidence we hold shows insufficient reliable evidence to rate their effectiveness for digestive complaints like indigestion (dyspepsia) or inflammatory bowel disease.
That doesn't mean they don't work; it means solid clinical trial data backing their use isn't established in our data.
How safe is it?
Well-documented data
Most of these enzymes are generally well tolerated when used as directed. Lactase specifically is likely safe in pregnancy.
However, the proteases may cause digestive upset or allergic reactions in some people, and one case of contact dermatitis and allergic reaction to lactase has been reported in an occupationally exposed worker. If you have a serious digestive condition, use this product only under medical guidance.
For pregnancy or breastfeeding, the data is limited on most ingredients: lactase is likely safe, but check with your doctor about the others before regular use.
Meds to double-check
No known interactions
No interactions are documented for the ingredients we could check. Use the medication checker on this page to verify your specific drugs just to be sure.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
If you're lactose intolerant, lactase here can help. For general digestive support, the evidence for the other enzymes isn't firmly established in our data.
If you have a serious digestive condition, get your doctor's okay first. Always check with your pharmacist, especially if you're pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Digestazyme, straight from the product label.
| Brand | Akasha Naturals |
|---|---|
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2024 |
| DSLD ID | 313107 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Digestazyme by Akasha Naturals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Lipase | 0 NP | -- |
| Lactase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Invertase | 0 NP | -- |
| Xylanase | 0 NP | -- |
| Pectinase | 0 NP | -- |
| Acid Protease | 0 NP | -- |
| Hemicellulase | 0 NP | -- |
| Neutral Protease | 0 NP | -- |
| Fungal Protease | 0 NP | -- |
| Proprietary Complete Enzyme Blend | 271 mg | -- |
Other ingredients: Hydroxypropyl Methylcellulose, Maltodextrin, Medium Chain Triglyceride
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Digestazyme provides digestive support with a non-GMO, broad spectrum of non-animal derived enzymes including acid stable lipase and three proteases that function in different pH ranges. This comprehensive enzyme complex is designed to support the healthy digestion of proteins, peptides, carbohydrates, fats, cellulose, maltose, lactose, and sucrose.
This product is non-GMO.
Broad spectrum digestive support
Suggested/Recommended/Usage/Directions
Directions: Take 2 capsules with each meal or as directed by your healthcare practitioner.
Precautions
Caution: If taking anti-diabetic medications, please consult your healthcare practitioner before use.
To report adverse events call 866-649-4334
Contains: Milk, wheat, and soy.
Storage
Storage: Keep tightly closed in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Digestazyme by Akasha Naturals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Digestazyme by Akasha Naturals
These are the 11 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Complete Enzyme Blend
- › Amylase
- › Lipase
- › Lactase
- › Cellulase
- › Invertase
- › Xylanase
- › Pectinase
- › Acid Protease
- › Hemicellulase
- › Neutral Protease
- › Fungal Protease
Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Maltodextrin, Medium Chain Triglyceride. These complete the product’s ingredient list but are not active constituents.
Digestazyme by Akasha Naturals Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Digestazyme. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Digestazyme, from the product label.
Akasha Naturals
See all Akasha Naturals products- Name
- Akasha Center for Integrative Medicine, LLC
- Street Address
- 520 Arizona Ave
- City
- Santa Monica
- State
- CA
- ZipCode
- 90401
- Phone Number
- 866-649-4334
- Web Address
- www.akashanaturals.com
Digestazyme by Akasha Naturals: Common Questions
Does Digestazyme by Akasha Naturals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help my lactose intolerance?
Is lactase safe if I'm pregnant?
Can I use this while breastfeeding?
What are proteases, and why are they in here?
Has anyone reported side effects from these enzymes?
Should I use this if I have Crohn's disease or ulcerative colitis?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Digestazyme is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Digestazyme’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
Digestazyme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC