Digestazyme Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Digestazyme against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Digestazyme is a dietary supplement by Akasha Naturals with 11 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Digestazyme by Akasha Naturals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Digestazyme is a blend of 11 digestive enzymes designed to help break down food. You get lipase (which breaks down fat), lactase (which breaks down the milk sugar lactose), and several proteolytic enzymes—acid protease, neutral protease, and fungal protease—that work on proteins.
The blend also contains amylase, cellulase, invertase, xylanase, pectinase, and hemicellulase to help with other carbohydrates and plant fiber. The inactive ingredients are hydroxypropyl methylcellulose (the capsule material), maltodextrin, and medium chain triglyceride.
Does it work?
Strong evidence
The evidence for most of these enzymes is still being worked out. Lactase is effective for lactose intolerance—that one's well established.
For lipase and the proteolytic enzymes, though, we don't have strong enough evidence yet to say they work for conditions like inflammatory bowel disease, dyspepsia (indigestion), or colic. The data just isn't there yet to rate them reliably.
How safe is it?
Well-documented data
These enzymes are generally well tolerated in most adults. That said, if you have a serious digestive condition, check with your doctor before using this product—it's best to make sure it won't interfere with your medical care.
Pregnancy and breastfeeding need some caution. Lactase is likely safe in pregnancy, but the others don't have enough safety data during pregnancy—your doctor should weigh in first.
For breastfeeding, there's limited data on most of these enzymes, so check with your healthcare provider. Rarely, people can be sensitive to proteolytic enzymes—allergic rhinitis or asthma have been reported with airborne exposure, and contact dermatitis and allergic reactions to lactase itself, though uncommon, have occurred.
Meds to double-check
No known interactions
No interactions are documented in our data for the digestive enzymes we could check in this product. That's good news—but it's not a guarantee that none exist.
If you take medications regularly, a quick check with your pharmacist before starting is always smart.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.
Digestazyme is a digestive enzyme blend that may help if you have trouble breaking down food, especially if you're lactose intolerant. Most people tolerate it well, but those with serious digestive issues or who are pregnant or breastfeeding should talk it over with their doctor or pharmacist first.
No medication interactions are documented for the ingredients we could check, but run your own medications through the tool on this page to be sure.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Digestazyme, straight from the product label.
| Brand | Akasha Naturals |
|---|---|
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2024 |
| DSLD ID | 313107 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Digestazyme by Akasha Naturals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Lipase | 0 NP | -- |
| Lactase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Invertase | 0 NP | -- |
| Xylanase | 0 NP | -- |
| Pectinase | 0 NP | -- |
| Acid Protease | 0 NP | -- |
| Hemicellulase | 0 NP | -- |
| Neutral Protease | 0 NP | -- |
| Fungal Protease | 0 NP | -- |
| Proprietary Complete Enzyme Blend | 271 mg | -- |
Other ingredients: Hydroxypropyl Methylcellulose, Maltodextrin, Medium Chain Triglyceride
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Digestazyme provides digestive support with a non-GMO, broad spectrum of non-animal derived enzymes including acid stable lipase and three proteases that function in different pH ranges. This comprehensive enzyme complex is designed to support the healthy digestion of proteins, peptides, carbohydrates, fats, cellulose, maltose, lactose, and sucrose.
This product is non-GMO.
Broad spectrum digestive support
Suggested/Recommended/Usage/Directions
Directions: Take 2 capsules with each meal or as directed by your healthcare practitioner.
Precautions
Caution: If taking anti-diabetic medications, please consult your healthcare practitioner before use.
To report adverse events call 866-649-4334
Contains: Milk, wheat, and soy.
Storage
Storage: Keep tightly closed in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Digestazyme by Akasha Naturals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Digestazyme by Akasha Naturals
These are the 11 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Complete Enzyme Blend
- › Amylase
- › Lipase
- › Lactase
- › Cellulase
- › Invertase
- › Xylanase
- › Pectinase
- › Acid Protease
- › Hemicellulase
- › Neutral Protease
- › Fungal Protease
Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Maltodextrin, Medium Chain Triglyceride. These complete the product’s ingredient list but are not active constituents.
Digestazyme by Akasha Naturals Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Digestazyme. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Digestazyme, from the product label.
Akasha Naturals
See all Akasha Naturals products- Name
- Akasha Center for Integrative Medicine, LLC
- Street Address
- 520 Arizona Ave
- City
- Santa Monica
- State
- CA
- ZipCode
- 90401
- Phone Number
- 866-649-4334
- Web Address
- www.akashanaturals.com
Digestazyme by Akasha Naturals: Common Questions
Does Digestazyme by Akasha Naturals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will Digestazyme help with lactose intolerance?
Is it safe to take during pregnancy?
Can I take it while breastfeeding?
What if I have a sensitive stomach or digestive condition?
Can I be allergic to these enzymes?
Do these enzymes actually work for indigestion and other digestive issues?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Digestazyme is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Digestazyme’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
Digestazyme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC