No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Digestive Enzymes pH Ingredients & Drug Interactions

by NHC Natural Healthy Concepts

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Digestive Enzymes pH is a dietary supplement by NHC Natural Healthy Concepts with 3 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Digestive Enzymes pH by NHC Natural Healthy Concepts

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 3 active ingredients.
  • “Newlase” is listed as a grouped ingredient — the label gives one combined amount (10 mg) without saying how much of each component you get.

This product has three active digestive enzymes. Protease breaks down proteins, lipase breaks down fats, and amylase breaks down carbohydrates — together they're meant to aid the digestion of food.

The rest is inactive ingredients: calcium carbonate, microcrystalline cellulose, and a few other binders and flow agents that make up the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support nutrient assimilation and food digestion.
  • We looked for evidence on: Dyspepsia, Pancreatic insufficiency, Malabsorption, Fat maldigestion.
  • The closest evidence on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia (Natural Medicines).

The evidence for these enzymes is limited. For lipase specifically, the data shows insufficient evidence to rate it for inflammatory bowel disease, dyspepsia (indigestion), or prematurity.

We don't hold effectiveness ratings for protease or amylase in the data we have. That means we can't tell you whether this product will actually help your digestion — the science isn't established enough in our files to say.

The evidence, ingredient by ingredient Lipase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease and lipase are generally well tolerated by most adults, but both can cause digestive upset or allergic reactions in some people. Anyone with a serious digestive condition should only use this under medical guidance.

Protease carries a rare risk: occupational exposure to related enzymes has triggered allergic reactions like runny eyes, sinus inflammation, or asthma in some people, though that's mainly from airborne exposure in industrial settings. For pregnancy, protease safety hasn't been established and is best avoided unless your doctor prescribes it.

Lipase also has little safety data in pregnancy — use only if advised by your doctor. Neither has solid safety data during breastfeeding, so check with your healthcare provider first if you're nursing.

Side effects, ingredient by ingredient Lipase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. We don't hold interaction information for amylase, so you won't find it in our search tool.

Run your medications through the checker on this page to be thorough.

The bottom line

Scorecard at a glancePartially disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

This is a basic digestive enzyme blend that's generally well tolerated by healthy adults. If you have a serious digestive condition like inflammatory bowel disease or if you're pregnant or breastfeeding, talk it over with your doctor or pharmacist first — the safety data is thin for those situations.

No medication interactions are documented, but check your exact medications to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Digestive Enzymes pH, straight from the product label.

Brand NHC Natural Healthy Concepts
Barcode (UPC) 647732924725
Net contents 180 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 230762
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Digestive Enzymes pH by NHC Natural Healthy Concepts, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
180
UPC/BARCODE
647732924725
IngredientAmount% DV
Protease0 NP--
Lipase10.2 mg--
Amylase45 mg--
Newlase10 mg--

Other ingredients: Calcium Carbonate, Microcrystalline Cellulose, HPMC, Stearic Acid, Silica, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Professional Use Only

This package is completely recyclable.

Suggested/Recommended/Usage/Directions

Directions: Take one capsule with or after each meal, or as directed by your healthcare practitioner.

Precautions

Consult your healthcare practitioner prior to use.

Individuals taking medication should discuss potential interactions with their healthcare practitioner.

Do not use if tamper seal is damaged.

Storage: Keep closed in a cool, dry place out of reach of children.

Formula

Digestive Enzymes pH is a blend of digestive enzymes derived from the fermentation action of fungi such as Aspergillus niger and Rhizopus nieves, microorganisms safely used in fermenting foods, including cheese, soy sauce, and yogurt.

Formulation

These non-animal derived enzymes support the assimilation of nutrients in foods and the digestion of proteins, carbohydrates, fats, and vegetable matter.

Digestive Enzymes pH is effective across a broad spectrum of pH ranges.

Does not contain: Wheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

Acid-resistant, non-animal derived digestive enzymes

Acid-resistant, non-animal derived digestive enzymes

Gluten free Dairy free Soy free Nut free

Manufactured in a GMP compliant facility.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Storage: Keep closed in a cool, dry place out of reach of children.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Vegetarian Caps

See for yourself

Digestive Enzymes pH by NHC Natural Healthy Concepts label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Digestive Enzymes pH by NHC Natural Healthy Concepts

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lipase

No known
interactions
10.2 mg per serving

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...

Lipase monograph & interactions

Amylase

45 mg per serving Form: Biodiastase 2000

Newlase

10 mg per serving

Other (inactive) ingredients: Calcium Carbonate, Microcrystalline Cellulose, HPMC, Stearic Acid, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Digestive Enzymes pH by NHC Natural Healthy Concepts Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Digestive Enzymes pH. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Digestive Enzymes pH, from the product label.

NHC Natural Healthy Concepts

See all NHC Natural Healthy Concepts products
Name
NHC
Street Address
310 N Westhill Blvd.
City
Appleton
State
WI
ZipCode
54914
Pharmacist Counseling Corner

Digestive Enzymes pH by NHC Natural Healthy Concepts: Common Questions

Does Digestive Enzymes pH by NHC Natural Healthy Concepts interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Digestive Enzymes pH. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Digestive Enzymes pH contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my indigestion?
Lipase — one of the three enzymes in here — hasn't been studied enough to say whether it works for indigestion. The evidence is too limited right now.
Are digestive enzymes safe if I have inflammatory bowel disease?
Anyone with a serious digestive condition like IBD should only take this under medical guidance. Talk to your doctor first — they know your situation best.
Can I take this while pregnant?
Protease safety in pregnancy hasn't been established and should be avoided unless prescribed. Lipase also has little safety data in pregnancy, so use only if your doctor advises it. Either way, check with your doctor before starting.
What's inside this product besides the enzymes?
The inactive ingredients are calcium carbonate, microcrystalline cellulose, and a few binders and flow agents — standard capsule fillers that help hold everything together.
Can this cause allergic reactions?
Both protease and lipase can trigger allergic reactions in some people. Protease also carries a rare occupational history of triggering allergic rhinoconjunctivitis or asthma through airborne exposure — though that's mainly a workplace risk, not typical consumer exposure.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Digestive Enzymes pH is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Digestive Enzymes pH label
Sources

Sources & How We Checked

Digestive Enzymes pH's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring