Double-Strength SAM-e 400 mg By Doctor's Best Overview & Drug Interactions
Check For Interactions With Double-Strength SAM-e 400 mg
Supplement: Double-Strength SAM-e 400 mg by Doctor's Best
Double-Strength SAM-e 400 mg Label Images
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
SAM-e
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same| Ingredient Group | SAM-e |
|---|---|
| Category | non-nutrient/non-botanical |
- S-Adenosyl-L-Methionine Disulfate P-Toluenesulfonate
Drugs that interact with Double-Strength SAM-e 400 mg by Doctor's Best
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
| Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
|---|---|
| Minimum serving Sizes: |
1 Tablet(s)
|
| Maximum serving Sizes: |
1 Tablet(s)
|
| Servings per container | 60 |
| UPC/BARCODE | 753950002524 |
| Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
|---|---|---|---|
| SAM-e |
400 mg
|
SAM-e |
--
|
| Other Ingredients: |
Microcrystalline Cellulose
Stearic Acid
Calcium Chloride Anhydrous
Magnesium Silicate
Magnesium Stearate
Magnesium Hydroxide
Flake Shellac dewaxed
Glycerol
Silica
Arginine
Sodium Alginate
Calcium Oxide
|
|---|
Label Statments:
| Formula |
- Doctor’s Best SAM-e helps replenish your SAM-e levels and promote a healthy mood. SAM-e (S-Adenosyl-L-Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody.
Supplementing with SAM-e
Soloesse Italian SAM-e is processed to yield the highest available percentage of the active pure S,S form which helps mediate biochemical activity in the human body.
- SAM-e and Mood and Cognitive Function
SAM-e helps facilitate DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body’s antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.
- SAM-e and Joint Function
In clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.
- SAM-e and Liver Function
SAM-e helps support healthy levels of glutathione, a critical antioxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.
- Doctor's Best utilizes only the highest quality Italian Soloesse SAM-e providing slow and targeted release for improved GI tolerance and absorption. Our Double-Strength SAM-e 400 contains 400 mg of active Soloesse SAM-e in each tablet. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.
|
|---|---|
| Brand IP Statement(s) |
- Soloesse is a registered trademark of Gnosis SpA.
- Science-Based Nutrition
|
| FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
|
| General |
- YDRB252-2
|
| FDA Statement of Identity |
- Dietary Supplement
|
| General Statements |
- Helps support mood and neural function
Helps support joint comfort and mobility
Helps support liver health and detoxification
- Double Strength SAM-e is sealed in blister packs for freshness and stability.
|
| Seals/Symbols |
- Vegetarian
|
| Formulation |
- Vegetarian
- Non-GMO
Gluten free
Soy free
|
| Suggested/Recommended/Usage/Directions |
- Suggested Adult Use: Take 1 tablet daily between meals, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.
|
| Precautions |
- Warning: Individuals using antidepressant medications should consult with their prescribing physician prior to using this product.
- Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe.
- Do not use if pregnant or nursing.
- May cause gastrointestinal discomfort in a small percentage of people.
- Do not chew or crush tablet.
|
| Storage |
- Store in a cool dry place.
|
Brand Information
See all products by this brand
| Manufactured for | |
|---|---|
| Name | Doctor's Best, Inc. |
| State | California |
| Country | USA |
| ZipCode | 92612 |
| Phone Number | (800) 777-2474 |
| Web Address | www.drbvitamins.com |
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.