Double-Strength SAMe 400 By Doctor's Best Overview & Drug Interactions
Check For Interactions With Double-Strength SAMe 400
Supplement: Double-Strength SAMe 400 by Doctor's Best
Double-Strength SAMe 400 Label Images
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
S-Adenosyl Methionine
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same| Ingredient Group | SAMe |
|---|---|
| Category | non-nutrient/non-botanical |
-
from 800 mg of SAM-e tosylate disulfate
Description:S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same
Ingredient Group SAMe Category non-nutrient/non-botanical
Drugs that interact with Double-Strength SAMe 400 by Doctor's Best
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
| Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
|---|---|
| Minimum serving Sizes: |
1 Tablet(s)
|
| Maximum serving Sizes: |
1 Tablet(s)
|
| Servings per container | 60 |
| UPC/BARCODE | 753950002524 |
| Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
|---|---|---|---|
| S-Adenosyl Methionine |
400 mg
|
SAMe |
--
|
| from 800 mg of SAM-e tosylate disulfate |
800 mg
|
SAMe |
|
| Other Ingredients: |
Cellulose Gel
Methacrylic Acid Copolymer
Compritol 888ATO
Talc
Triethyl Citrate
Titanium Dioxide
Magnesium Stearate
Mannitol
Glycerol Palmitostearate
Silica
Medium Chain Triglycerides
Sodium Starch Glycolate
Iron Oxide
|
|---|
Label Statments:
| General Statements |
- S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Mehtylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissues including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.
- Supplementing with SAMe
The manufacturing process of SAMe yields two forms, the S,S and R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in our SAMe 400 is processed to yield the highest available percentage of the active pure S,S form on the market.
- SAMe and Joint Function
SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential somponents of connective tissue. Clinical studies show and ability of SAMe to enhance mobility and movement, and promote joint comfort.
- SAMe and Neural Health
SAMe-catalyzed methylation reactions promote he symthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidycholine, supporting cognitive function.
- SAMe and Liver Function
SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver protection. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.
- Doctor's Best utilizes only the highest quality Italian SAMe available on e market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none.
- Enhances Mood & Neural Function
Promotes Joint Comfort & Mobility
Supports Liver Health & Detoxification
Pharmaceutical Grade
Made in Italy
- CONTAINS NOTHING OTHER THAN LISTED INGREDIENTS
|
|---|---|
| FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
|
| Formula |
- Our Double-Strength SAMe 400 contains 400mg of active SAMe in each tablet.
- Dietary Supplement with 400mg Active S-Adenosyl Methionine Per Tablet
|
| Storage |
- Double-Strength SAMe is sealed in blister packs for freshness and stability. Store product in a cool, dry place to ensure maximum quality.
- Sealed in Blister Packs for Freshness & Convenience
|
| Brand IP Statement(s) |
- Science-Based Nutrition(TM)
|
| FDA Statement of Identity |
- Dietary Supplement with 400mg Active S-Adenosyl Methionine Per Tablet
|
| Suggested/Recommended/Usage/Directions |
- Suggested Adult Use: Take 1 tablet daily away from food, or as directed by a health care professional. Do not chew or crush tablet.
|
| Precautions |
- Individuals using antidepressant medications should consult with their prescribing physician prior to using this product.
- Individuals diagnosed wit bipolar disease or manic depression should avoid supplementing with SAMe.
- Do not use if pregnant or nursing.
- May cause gastrointestinal discomfort is a small percentage of people.
|
| Formulation |
- The SAMe found in Doctor's Best SAMe 400mg (Double Strength) is free from yeast, dairy, gluten, soy, wheat, and artificial flavoring.
- Suitable for Vegetarians
|
| General |
- P 03/11
|
Brand Information
See all products by this brand
| Distributed by | |
|---|---|
| Name | Doctor's Best, Inc. |
| City | San Clemente |
| State | CA |
| ZipCode | 92673 |
| Phone Number | (800) 777-2474 |
| Web Address | www.drbvitamins.com |
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.