Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Endo Rush Citrus Ingredients & Drug Interactions

by BSN

Endo Rush Citrus label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Endo Rush Citrus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Endo Rush Citrus is a dietary supplement by BSN with 3 active ingredients. Its ingredients are commonly taken for athletic performance and endurance, high-intensity exercise capacity, reducing muscle fatigue.Based on those ingredients, 811 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Caffeine, Theacrine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Endo Rush Citrus by BSN

Ask about any prescription or over-the-counter medication and we check it for interactions with Endo Rush Citrus by BSN — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Endo Rush Citrus by BSN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Endo Rush Citrus has 3 active ingredients: CarnoSyn (beta-alanine), theacrine, and caffeine. Beta-alanine is an amino acid used to support athletic and physical performance.

Theacrine is a purine alkaloid related to caffeine; its roles in the body aren't yet well established. Caffeine is a stimulant that boosts mental alertness and athletic performance.

The product also contains inactive ingredients (carbonated water, citric acid, natural and artificial flavor, phosphoric acid, potassium sorbate, potassium benzoate, sucralose, tartaric acid, and acesulfame potassium) that give it taste, texture, and shelf life.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: pre-workout performance and athletic endurance support.
  • We looked for evidence on: Athletic performance, Physical performance, Exercise-induced muscle breakdown, Exercise-induced muscle soreness, Muscle strength, Fatigue — and 4 related terms.
  • The strongest evidence on file: Caffeine is rated "Likely Effective" for Athletic performance (Natural Medicines).
  • Also on file: Caffeine is rated "Likely Effective" for Mental alertness.
  • Also on file: Beta-alanine is rated "Possibly Effective" for Athletic performance, Physical performance.

Caffeine is well proven: it's effective for postoperative headache and neonatal apnea, and likely effective for mental alertness and athletic performance. Beta-alanine (CarnoSyn) is possibly effective for athletic and physical performance, but evidence is insufficient for age-related cognitive decline, COPD, menopausal symptoms, or general cognitive function.

Theacrine's effectiveness isn't established — the evidence we hold rates all its proposed uses (alertness, fatigue, cognitive function, muscle strength, athletic performance) as insufficient to draw conclusions.

The evidence, ingredient by ingredient Beta-alanine Theacrine Caffeine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-alanine is generally well tolerated but commonly causes a harmless tingling sensation (paresthesia) and flushing, especially on the scalp, starting within 20 minutes and lasting about an hour. The tingling's severity depends on dose — it was mild or absent in many people at lower doses.

Theacrine appears generally well tolerated in the short term, but long-term safety isn't established. Caffeine in moderate amounts is generally safe for healthy adults but can cause anxiety, jitteriness, insomnia, nausea, tremors, headache, and stomach upset; high doses carry serious risks.

Pregnancy and breastfeeding: beta-alanine and theacrine both lack safety data, so the advice is to avoid them during pregnancy and while breastfeeding. Caffeine is rated possibly safe in pregnancy at some doses and possibly unsafe at others — talk with your doctor about safe limits for you.

Small amounts of caffeine pass into breast milk; moderate intake is usually considered acceptable but can affect the baby.

Side effects, ingredient by ingredient Beta-alanine Theacrine Caffeine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Caffeine, Theacrine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 811 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Endo Rush Citrus, check with your doctor or pharmacist if you take ephedrine or related stimulants (Major interaction risk). Also double-check if you're on CNS depressants (sedating drugs), barbiturates, carbamazepine or other anticonvulsants, clozapine, cimetidine, quinolone antibiotics, or dipyridamole — all have documented Moderate interactions with the caffeine in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is marketed for athletic and physical performance, where caffeine and beta-alanine have supporting evidence. If you're healthy, don't take stimulants or certain other medications, and don't mind the tingling that beta-alanine causes, it may be worth a try.

However, if you take any prescription drugs — especially stimulants, sedatives, anticonvulsants, or antibiotics — talk with your doctor or pharmacist first, because the caffeine in this product has documented interactions with many common medications. Pregnant people and those breastfeeding should discuss use with their own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Endo Rush Citrus, straight from the product label.

Brand BSN
Barcode (UPC) 834266007462
Net contents 16 fl. Oz.; 473 mL
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 201174
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Endo Rush Citrus by BSN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
16 fl. Oz.
Maximum serving Sizes:
16 fl. Oz.
UPC/BARCODE
834266007462
IngredientAmount% DV
Calories0 Calorie(s)--
Total Sugars0 Gram(s)--
CarnoSyn1.5 Gram(s)--
Theacrine25 mg--
Caffeine350 mg--

Other ingredients: carbonated Water, Citric Acid, Natural and Artificial flavor, Phosphoric Acid, Potassium Sorbate, Potassium Benzoate, Sucralose, Tartaric Acid, Acesulfame Potassium

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Zero sugar

No artificial colors Zero calories 0 g sugar

Suggested/Recommended/Usage/Directions

Directions: Drink 1 can 15 - 30 minutes prior to your workout. To support hydration, drink plenty of water throughout your workout.

Precautions

Warning: Consult your physician before using this product if you are taking any medications or are under a physician’s care for a medical condition. Not for use by those under the age of 18, women that are pregnant, trying to get pregnant, or nursing, or those that are sensitive to caffeine or beta-alanine.

Not for use by those under the age of 18, women that are pregnant, trying to get pregnant, or nursing, or those that are sensitive to caffeine or beta-alanine.

Do not consume caffeine from other sources while taking this product as too much caffeine may cause nervousness, irritability, sleeplessness, and occasionally rapid heartbeat. Beta-alanine may cause a harmless, temporary tingling or flushing sensation. Do not combine with alcohol. Do not exceed 1 serving within any 24 hour period. Consume as part of a healthy diet and exercise program, and drink at least 100 fl oz of water per day. Exercise may increase your need for fluid intake.

High caffeine content (350 mg) read entire label before consuming.

Formula

Do not consume caffeine from other sources while taking this product as too much caffeine may cause nervousness, irritability, sleeplessness, and occasionally rapid heartbeat. Beta-alanine may cause a harmless, temporary tingling or flushing sensation.

Total Caffeine in 350 mg per serving.

350 mg caffeine 25 mg Teacrine 1.5 g beta-alanine

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease

General

V.4.746.0718US 6048508

Brand IP Statement(s)

Finish First.

TeaCrine is a registered trademark and Protected by Patents Pending, Serial No. 61/903,362; under exclusive global distribution by Compound Solutions, Inc. Natural Alternatives International (NAI) is the owner of patents as listed on www.carnosyn.com and registered trademark CarnoSyn.

General Statements

Energy & performance pre-workout Naturally & artificially flavored

This product contains ingredients of international and domestic origin

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Manufactured in the USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Endo Rush Citrus by BSN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Endo Rush Citrus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Endo Rush Citrus by BSN

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size16 fl. Oz. Dosage formLiquid Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

CarnoSyn

No known
interactions
1.5 Gram(s) per serving Form: Beta-Alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...

CarnoSyn monograph & interactions

Theacrine

Interacts with
248 drugs
25 mg per serving

Theacrine is a caffeine-like compound found naturally in certain tea plants and is sold in supplements for energy, focus, and mood. Early human studie...

Theacrine monograph & interactions

Caffeine

Interacts with
655 drugs
350 mg per serving

Caffeine is a natural stimulant found in coffee, tea, and many other plants and products. In moderate amounts it can boost alertness and reduce tiredn...

Caffeine monograph & interactions

Other (inactive) ingredients: Carbonated Water, Citric Acid, Natural and Artificial flavor, Phosphoric Acid, Potassium Sorbate, Potassium Benzoate, Sucralose, Tartaric Acid, Acesulfame Potassium. These complete the product’s ingredient list but are not active constituents.

Interaction report

Endo Rush Citrus by BSN Drug Interactions

Want to check YOUR meds against Endo Rush Citrus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
811Drugs
8 Major 646 Moderate 157 Minor

Ingredients driving the most interactions

Caffeine 655
Theacrine 248

Individual Drug Interactions

The ingredients in Endo Rush Citrus interact with 811 drugs. Click any drug to see the details.

2 of the 3 ingredients in Endo Rush Citrus interact with drugs. Each result below shows which ingredient is responsible. Caffeine Theacrine

Each ingredient & the kinds of drugs it affects

For each ingredient in Endo Rush Citrus with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Caffeine41 drug types · 655 drugs

Ephedrine

Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Use of ephedrine with caffeine can increase the risk of stimulatory adverse effects. There is evidence that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction, stroke, seizures, and death.

Likelihood Probable Evidence D
Adenosine (Adenocard)

Theoretically, caffeine might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Some evidence shows that caffeine is a competitive inhibitor of adenosine and can reduce the vasodilatory effects of adenosine in humans. However, other research shows that caffeine does not seem to affect supplemental adenosine because high interstitial levels of adenosine overcome the antagonistic effects of caffeine. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. However, methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.

Likelihood Possible Evidence B
Anticoagulant/Antiplatelet Drugs

Theoretically, caffeine may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Caffeine is reported to have antiplatelet activity. Theoretically, it might increase the risk of bleeding when used concomitantly with these agents; however, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Beta-Adrenergic Agonists

Theoretically, large amounts of caffeine might increase the cardiac inotropic effects of beta-agonists.

Likelihood Probable Evidence D
Carbamazepine (Tegretol)

Theoretically, caffeine might reduce the effects of carbamazepine and increase the risk for convulsions.
Animal research suggests that taking caffeine can lower the anticonvulsant effects of carbamazepine and can induce seizures when taken in doses above 400 mg/kg. Human research has shown that taking caffeine 300 mg in three divided doses along with carbamazepine 200 mg reduces the bioavailability of carbamazepine by 32% and prolongs the plasma half-life of carbamazepine 2-fold in healthy individuals.

Likelihood Possible Evidence D
Cimetidine (Tagamet)

Theoretically, cimetidine might increase the levels and adverse effects of caffeine.
Cimetidine decreases the rate of caffeine clearance by 31% to 42%.

Likelihood Likely Evidence B
Clozapine (Clozaril)

Caffeine might increase the levels and adverse effects of clozapine and acutely exacerbate psychotic symptoms.
Caffeine might increase the effects and toxicity of clozapine. Caffeine doses of 400-1000 mg per day inhibit clozapine metabolism. Clozapine is metabolized by cytochrome P450 1A2 (CYP1A2). Although researchers speculate that caffeine might inhibit CYP1A2, there is no reliable evidence that caffeine affects CYP1A2. There is also speculation that genetic factors might make some patients more sensitive to an interaction between clozapine and caffeine. In one case report, severe, life-threatening clozapine toxicity and multiorgan system failure occurred in a patient with schizophrenia stabilized on clozapine who consumed caffeine 600 mg daily.

Likelihood Possible Evidence B
Dipyridamole (Persantine)

Theoretically, caffeine might decrease the vasodilatory effects of dipyridamole and interfere with its use prior to stress testing.
Caffeine inhibits dipyridamole-induced vasodilation. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. Methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.

Likelihood Probable Evidence B
Disulfiram (Antabuse)

Theoretically, disulfiram use might increase the levels and adverse effects of caffeine.
Disulfiram decreases the rate of caffeine clearance.

Likelihood Probable Evidence B
Diuretic Drugs

Theoretically, using caffeine with diuretic drugs might increase the risk of hypokalemia.
Caffeine, especially in excessive amounts, can reduce potassium levels due to stimulation of the sodium-potassium pump. Diuretics can also cause lower potassium levels.

Likelihood Possible Evidence D
Estrogens

Theoretically, estrogens might increase the levels and adverse effects of caffeine.
Estrogen inhibits caffeine metabolism.

Likelihood Probable Evidence B
Ethosuximide (Zarontin)

Theoretically, caffeine might reduce the effects of ethosuximide and increase the risk for convulsions.
Animal research suggests that caffeine 92.4 mg/kg can decrease the anticonvulsant activity of ethosuximide. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Felbamate (Felbatol)

Theoretically, caffeine might reduce the effects of felbamate and increase the risk for convulsions.
Animal research suggests that a high dose of caffeine 161.7 mg/kg can decreases the anticonvulsant activity of felbamate. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Flutamide (Eulexin)

Theoretically, caffeine might increase the levels and adverse effects of flutamide.
In vitro evidence suggests that caffeine can inhibit the metabolism of flutamide. However, this effect has not been reported in humans.

Likelihood Probable Evidence D
Fluvoxamine (Luvox)

Theoretically, fluvoxamine might increase the levels and adverse effects of caffeine.
Fluvoxamine reduces caffeine metabolism.

Likelihood Probable Evidence D
Lithium

Abrupt caffeine withdrawal might increase the levels and adverse effects of lithium.
Caffeine has diuretic activity. When abruptly discontinued, caffeine may alter the clearance of lithium. There are two case reports of lithium tremor that worsened upon abrupt coffee withdrawal and 6 case reports of elevated serum lithium levels after reducing or eliminating caffeine intake. In one case, a male with schizoaffective disorder stabilized on lithium had an elevated lithium level after reducing his caffeine intake by 87%. At a later date, he increased his caffeine intake by 6-fold, resulting in a subtherapeutic lithium level and a recurrence of psychiatric symptoms.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use might increase the risk of a hypertensive crisis.
Caffeine has been shown to inhibit monoamine oxidase (MAO) A and B in laboratory studies. Concomitant intake of large amounts of caffeine with MAOIs might precipitate a hypertensive crisis. In a case report, a patient that consumed 10-12 cups of caffeinated coffee and took the MAOI tranylcypromine presented with severe hypertension. Hypertension was resolved after the patient switched to drinking decaffeinated coffee.

Likelihood Possible Evidence D
Nicotine

Theoretically, concomitant use might increase the risk of hypertension.
Concomitant use of caffeine and nicotine has been shown to have additive cardiovascular effects, including increased heart rate and blood pressure. Blood pressure was increased by 10.8/12.4 mmHg when the agents were used concomitantly.

Likelihood Probable Evidence B
Pentobarbital (Nembutal)

Theoretically, caffeine might decrease the effects of pentobarbital.
Caffeine might negate the hypnotic effects of pentobarbital.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

Theoretically, caffeine might reduce the effects of phenobarbital and increase the risk for convulsions.
Animal research suggests that caffeine can decrease the anticonvulsant activity of phenobarbital. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Phenylpropanolamine

Theoretically, phenylpropanolamine might increase the risk of hypertension, as well as the levels and adverse effects of caffeine.
Concomitant use of phenylpropanolamine and caffeine might cause an additive increase in blood pressure. Phenylpropanolamine also seems to increase caffeine serum levels.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Theoretically, caffeine might reduce the effects of phenytoin and increase the risk for convulsions.
Animal research suggests that caffeine can decrease the anticonvulsant activity of phenytoin. The effect does not seem to be related to the seizure threshold-lowering effects of caffeine. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Pioglitazone (Actos)

Theoretically, caffeine might increase the levels and clinical effects of pioglitazone.
Animal research suggests that caffeine can modestly increase the maximum concentration, area under the curve, and half-life of pioglitazone, and also reduce its clearance. This increased the antidiabetic effects of pioglitazone. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.
Quinolones (also called fluoroquinolones) can decrease caffeine clearance by inhibiting cytochrome P450 1A2 (CYP1A2) enzyme.

Likelihood Probable Evidence B
Riluzole (Rilutek)

Theoretically, concomitant use might increase the levels and adverse effects of both caffeine and riluzole.
Caffeine and riluzole are both metabolized by cytochrome P450 1A2 (CYP1A2), and concomitant use might reduce the metabolism of one or both agents.

Likelihood Possible Evidence D
Caffeine full monograph & all 41 interactions

Theacrine1 drug type · 248 drugs

Cns Depressants

Theoretically, theacrine might alter the effects of CNS depressants.
Animal research shows that low doses of theacrine have sedating effects, whereas high doses might have stimulant effects. Depending on the dose of theacrine used, it might increase or decrease the effects of CNS depressants. However, these effects have not yet been reported in humans.

Likelihood Possible Evidence D
Theacrine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Endo Rush Citrus, from the product label.

BSN

See all BSN products
Name
Bio-Engineered Supplements & Nutrition, Inc.
Street Address
3500 Lacey Road, Suite 1200
City
Downers Grove
State
IL
ZipCode
60515
Phone Number
877.673.3727
Web Address
www.goBSN.com
Pharmacist Counseling Corner

Endo Rush Citrus by BSN: Common Questions

Does Endo Rush Citrus by BSN interact with any medications?
Yes. Based on its ingredients, Endo Rush Citrus has a known interaction with 811 medications, including 8 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Endo Rush Citrus contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this actually help my athletic performance?
Caffeine is well supported for athletic performance, and beta-alanine (CarnoSyn) is possibly effective for athletic and physical performance — so there's a real basis for trying it. Theacrine's role in performance isn't established in the data we hold. Results vary from person to person.
What's that tingling feeling I might get?
That's paresthesia from the beta-alanine — a harmless pins-and-needles sensation, usually on the scalp first, that starts within 20 minutes and lasts about an hour. It's common, dose-dependent (milder at lower doses, more noticeable at higher ones), and goes away on its own. It's not dangerous.
Is it safe to take while pregnant?
The data advises against beta-alanine and theacrine during pregnancy because there isn't enough safety information. Caffeine's pregnancy safety is mixed — possibly safe at some doses, possibly unsafe at others. Talk with your doctor about whether it's right for you.
Can I take this if I'm breastfeeding?
Beta-alanine and theacrine lack safety data for breastfeeding, so the advice is to avoid them. Caffeine passes into breast milk in small amounts; moderate caffeine intake is usually considered acceptable but can affect the baby. Discuss what's safe for you with your pharmacist or doctor.
What if I'm on a sleeping pill or antidepressant — can I use this?
This product may affect those types of medications because of its caffeine and theacrine content. Don't start it without checking with your doctor or pharmacist first — they can tell you whether it's safe with your specific drugs.
How much caffeine is in one serving?
The product facts we have don't list the caffeine dose per serving, so you'll need to check the label or contact the manufacturer for that detail.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Endo Rush Citrus label
Go deeper

The Full Monographs Behind Endo Rush Citrus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...

Read the full Beta-alanine monograph → Herb & supplement monograph

Theacrine

Interacts with 248 drugs

Theacrine is a caffeine-like compound found naturally in certain tea plants and is sold in supplements for energy, focus, and mood. Early human studies suggest it may give a stimulant-like b...

Read the full Theacrine monograph → Herb & supplement monograph

Caffeine

Interacts with 655 drugs

Caffeine is a natural stimulant found in coffee, tea, and many other plants and products. In moderate amounts it can boost alertness and reduce tiredness for most healthy adults, but too muc...

Read the full Caffeine monograph →
Sources

Sources & How We Checked

Endo Rush Citrus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 250 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-alanine 13 references
  1. Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
  2. Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
  3. Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
  4. Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
  5. Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
  6. Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
  7. Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
  8. Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
  9. Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
  10. Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
  11. da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
  12. Varanoske AN, Hoffman JR, Church DD, et al. Comparison of sustained-release and rapid-release ß-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol. Amino Acids. PubMed
  13. Perim P, Gobbi N, Duarte B, et al. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. Eur J Sport Sci 2021. PubMed

See these in context on the Beta-alanine monograph →

Theacrine 1 reference
  1. Xu JK, Kurihara H, Zhao L, Yao XS. Theacrine, a special purine alkaloid with sedative and hypnotic properties from Cammelia assamica var. kucha in mice. J Asian Nat Prod Res 2007;9(6-8):665-72.

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