No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Enzyme Probiotic Complex+ Ingredients & Drug Interactions

by American Health

Capsule Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Enzyme Probiotic Complex+ is a dietary supplement by American Health with 4 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Enzyme Probiotic Complex+ by American Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 4 active ingredients.
  • “Enzyme Blend” is a proprietary blend — the label gives one combined amount (350 mg) without saying how much of each component you get.

This product has 4 active ingredients: an enzyme blend (Amylase, Lipase, and Protease) plus Lactobacillus plantarum Lp299v, a probiotic strain. The enzymes are meant to help break down food — amylase works on carbohydrates, lipase on fats, and protease on proteins.

The probiotic is a beneficial bacterium that may support digestive health. The remaining ingredients are capsule fillers and binders (cellulose, gelatin, maltodextrin, magnesium stearate, and silica).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: digestive enzyme and probiotic support.
  • We looked for evidence on: Dyspepsia, indigestion, bloating, digestive discomfort, malabsorption.
  • The closest evidence on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia (Natural Medicines).

The evidence for these ingredients isn't solid. For lipase, we hold ratings of insufficient evidence for inflammatory bowel disease, dyspepsia (indigestion), and prematurity — meaning the studies aren't strong enough to know if it works.

We have no effectiveness ratings on file for protease, amylase, or the Lactobacillus plantarum strain, so we can't tell you whether the evidence supports their use for any specific condition.

The evidence, ingredient by ingredient Lipase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase and protease are both generally well tolerated in adults, though protease may cause digestive upset or allergic reactions in some people. If you have a serious digestive condition, use lipase only under medical guidance.

During pregnancy, the safety data on supplemental lipase is thin — use it only if your doctor advises. For breastfeeding, neither lipase nor protease has been well studied; check with your healthcare provider first.

Protease is normally safe in food, but occupational exposure to airborne protease has occasionally triggered allergic rhinitis or asthma in workers.

Side effects, ingredient by ingredient Lipase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, check your exact medications with the tool on this page — we don't have data on Amylase or Lactobacillus plantarum, so we can't rule out interactions entirely.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

This is a digestive enzyme and probiotic blend with no documented drug interactions. Because the effectiveness evidence is weak or missing, it's hard to say who it's best for.

If you have a serious digestive condition or are pregnant or breastfeeding, talk to your pharmacist or doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Enzyme Probiotic Complex+, straight from the product label.

Brand American Health
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 317675
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Enzyme Probiotic Complex+ by American Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
IngredientAmount% DV
Enzyme Blend350 mg--
Amylase0 NP--
Lipase0 NP--
Protease0 NP--
Lactobacillus plantarum Lp299v30 mg--

Other ingredients: Cellulose, Gelatin, Maltodextrin, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Contains wheat and soy ingredients.

Storage

Guaranteed quality and CFU through expiration when continuously stored in the original packaging as directed. Store in a cool, dry place away from direct sunlight.

No refrigeration required.

Brand IP Statement(s)

Lp299v and Probi Digestis are registered trademarks of Probi

Copyright 2021 American Health, Inc

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Visit www.AmericanHealthUS.com for our complete line of products.

Formulation

Advanced support for gas & bloating For broad spectrum Activity Clinically-Studied Strain Guaranteed potency through expiration

Non-GMO

No dairy, no tree nuts, no peanuts, no sugar, no starch, no yeast, no fish, no sodium, no artificial color, no artificial flavor, no artificial sweetener.

Formula

20 Billion Live Probiotic Cultures 3 Naturally-Based Enzymes

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, take one (1) capsule daily with a meal.

See for yourself

Enzyme Probiotic Complex+ by American Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Enzyme Probiotic Complex+ by American Health

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Enzyme Blend

350 mg per serving

Lactobacillus plantarum Lp299v

30 mg per serving

Other (inactive) ingredients: Cellulose, Gelatin, Maltodextrin, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Enzyme Probiotic Complex+ by American Health Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Enzyme Probiotic Complex+. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Enzyme Probiotic Complex+, from the product label.

American Health

See all American Health products
Name
American Health, Inc.
City
Ronkonkoma
State
NY
ZipCode
11779
Phone Number
800-445-7137
Web Address
www.AmericanHealthUS.com
Pharmacist Counseling Corner

Enzyme Probiotic Complex+ by American Health: Common Questions

Does Enzyme Probiotic Complex+ by American Health interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Enzyme Probiotic Complex+. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Enzyme Probiotic Complex+ contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with my indigestion?
We don't have reliable evidence that lipase (or the other enzymes in this blend) actually works for indigestion. The data we hold shows insufficient evidence, so we can't say whether it will help you.
Can I take this if I'm pregnant?
There's not enough safety data on supplemental lipase in pregnancy, so the advice is to use it only if your doctor tells you to. For protease, safety has not been established during pregnancy, so it's best avoided unless prescribed. Talk with your doctor before starting.
What does each enzyme in this product do?
Amylase helps break down carbohydrates, lipase breaks down fats, and protease breaks down proteins. Together they're meant to support your digestion, though the evidence that they do is weak.
Could protease cause an allergic reaction?
Protease may cause allergic reactions in some people. Occupational exposure to airborne protease has rarely triggered allergic rhinitis or asthma in workers, but reactions in supplement users are uncommon.
Is it safe to take this while breastfeeding?
Safety during breastfeeding has not been well studied for either lipase or protease. Don't use this without checking with your healthcare provider first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Enzyme Probiotic Complex+ is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Enzyme Probiotic Complex+ label
Sources

Sources & How We Checked

Enzyme Probiotic Complex+'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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