No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 4 of 20 ingredients. Check your meds →
Dietary supplement

ET-Zymes Complete Ingredients & Drug Interactions

by Adaptogen Research

Capsule Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

ET-Zymes Complete is a dietary supplement by Adaptogen Research with 20 active ingredients. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of ET-Zymes Complete by Adaptogen Research

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 20 active ingredients.
  • “Carbohydrate Specific Enzymes” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Sugar Specific Enzymes” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Vegetable/Plant Fiber Specific Enzymes” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

ET-Zymes Complete is a 20-ingredient enzyme blend designed to support digestion. The active ingredients are digestive enzymes — proteins that break down food — including Lipase (fat breakdown), Lactase (milk sugar), Cellulase (plant fiber), Glucoamylase and Alpha-Amylase (starch), Acid Protease and Alkaline Proteases (protein), Phytase (mineral availability), Sucrase and Maltase (simple sugars), and several others organized into specialized groups for carbohydrates, proteins, and plant fibers.

The product also contains inactive ingredients: a vegetarian capsule, coconut oil powder, and microcrystalline cellulose (a binder).

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: comprehensive enzyme supplement.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, indigestion, bloating, gas, fat malabsorption.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

The evidence for most of these enzymes is not yet established. Lactase is the one exception — it is considered effective for lactose intolerance.

For the others, the data we hold shows insufficient reliable evidence to rate how well they work for inflammatory bowel disease, dyspepsia (indigestion), prematurity, colic, aging skin, iron deficiency anemia, zinc deficiency, child growth, and blepharospasm. This doesn't mean they don't work; it means rigorous trials haven't been completed yet.

The evidence, ingredient by ingredient Lactase Phytase Proteolytic Enzymes (proteases) Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase, Lactase, and Phytase are generally well tolerated in supplement form, though people with serious digestive conditions should use them only under medical guidance. The proteolytic enzymes (Acid Protease and Alkaline Proteases) are also generally well tolerated for most adults but may cause digestive upset or allergic reactions in some people.

Rare occupational exposure to airborne protease or phytase has triggered allergic reactions and asthma in workers; typical oral use carries a much lower risk. For pregnancy, the safety picture is mixed.

Lactase is likely safe during pregnancy. Lipase, Phytase, and the proteolytic enzymes have insufficient data — check with your doctor before regular use.

For breastfeeding, limited data exists for most of these; ask your doctor or pharmacist first. A rare case of contact dermatitis from lactase powder exposure has been reported, and premature infants given certain lipase products have experienced gastrointestinal side effects.

Side effects, ingredient by ingredient Lactase Phytase Proteolytic Enzymes (proteases) Lipase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 4 matched ingredients has a documented medication interaction on file.

No interactions are documented for the enzyme ingredients we could check in this product. However, we hold no data for several blend components, so if you take any medications and want to be thorough, use the search tool on this page or ask your doctor or pharmacist.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

ET-Zymes Complete is an enzyme blend intended to support digestion. Lactase in it is well-studied for milk sugar intolerance; the others have little rigorous evidence but are generally well tolerated by adults.

If you have serious digestive conditions, are pregnant, breastfeeding, or take prescription medications, talk with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 20 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ET-Zymes Complete, straight from the product label.

Brand Adaptogen Research
Barcode (UPC) 828054746497
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 246976
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ET-Zymes Complete by Adaptogen Research, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
828054746497
IngredientAmount% DV
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Glucoamylase0 NP--
Alpha-Galactosidase0 NP--
Acid Protease0 NP--
Phytase0 NP--
Amylases0 NP--
Alpha-Amylase0 NP--
Sucrase0 NP--
Lysozyme0 NP--
Comprehensive Enzyme Blend800 mg--
Carbohydrate Specific Enzymes0 NP--
Sugar Specific Enzymes0 NP--
Maltase0 NP--
Pullulanase0 NP--
Vegetable/Plant Fiber Specific Enzymes0 NP--
Hemicellulase/Pectinase/Phytase Complex0 NP--
Beta Glucanase0 NP--
Galactomannase0 NP--
Protein and Peptide Specific Enzymes0 NP--
Alkaline Proteases0 NP--
Protease/Peptidase Complex0 NP--
Fat Specific Enzymes0 NP--
Other Enzymes0 NP--
Serratia peptidase0 NP--

Other ingredients: Vegetarian Capsule, Coconut Oil powder, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Comprehensive Enzyme Supplement

Produced under a strict quality management system in compliance with Good Manufacturing Practices (GMPs) and third-party quality certifications.

Notice: Color, size or shape may appear different between lots.

General Statements

Professional Use Only

Units are those used in Food Chemicas Codex (FCC)

Precautions

Contains: Egg and tree nut (coconut).

Report any adverse reactions to (302) 213-0030

Caution: If you are pregnant, nursing, have a medical condition, taking prescription drugs, or are allergic to eggs, consult your healthcare professional before using this product.

Keep out of reach of children.

Do not use if shrinkwrap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant, nursing, have a medical condition, taking prescription drugs, or are allergic to eggs, consult your healthcare professional before using this product.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 2 capsules at the beginning of each meal or as directed by your healthcare practitioner.

Brand IP Statement(s)

Peptizyme SP a registered trademark of Specialty Enzymes

Store in a cool, dry place (59 degrees F-85 degrees F) away from direct light.

See for yourself

ET-Zymes Complete by Adaptogen Research label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in ET-Zymes Complete by Adaptogen Research

These are the 20 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Comprehensive Enzyme Blend

800 mg per serving

Carbohydrate Specific Enzymes

0 NP per serving
  • › Glucoamylase
  • › Amylases
  • › Alpha-Amylase

Sugar Specific Enzymes

0 NP per serving
  • Lactase
  • › Sucrase
  • › Maltase
  • › Pullulanase

Vegetable/Plant Fiber Specific Enzymes

0 NP per serving
  • › Cellulase
  • › Alpha-Galactosidase
  • Phytase
  • › Hemicellulase/Pectinase/Phytase Complex
  • › Beta Glucanase
  • › Galactomannase

Protein and Peptide Specific Enzymes

0 NP per serving

Fat Specific Enzymes

0 NP per serving

Other Enzymes

0 NP per serving
  • › Lysozyme
  • › Serratia peptidase

Other (inactive) ingredients: Vegetarian Capsule, Coconut Oil powder, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

ET-Zymes Complete by Adaptogen Research Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in ET-Zymes Complete. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for ET-Zymes Complete, from the product label.

Adaptogen Research

See all Adaptogen Research products
Name
Adaptogen Research
Street Address
625 Barksdale Road, Suite 113
City
Newark
State
DE
ZipCode
19711
Phone Number
302-213-0030
Pharmacist Counseling Corner

ET-Zymes Complete by Adaptogen Research: Common Questions

Does ET-Zymes Complete by Adaptogen Research interact with any medications?
We do not currently list a known interaction for the mapped ingredients in ET-Zymes Complete. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
ET-Zymes Complete contains 20 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my lactose intolerance?
Yes — Lactase, one of the ingredients, is considered effective for lactose intolerance. The other enzymes in the blend support broader digestion, though the evidence for those is not yet established.
Can I take this while pregnant?
Lactase is likely safe during pregnancy. The others — Lipase, Phytase, and the proteolytic enzymes — don't have enough safety data yet. Check with your doctor before regular use.
Is this safe while breastfeeding?
Limited data exist for most of these enzymes during breastfeeding. Ask your doctor or pharmacist first before regular use.
What does Phytase do?
Phytase is an enzyme that may help your body absorb certain minerals from plant foods, though the evidence for this is still developing. It's generally considered low-risk in food sources, but human supplement data are limited.
Are there any side effects?
These enzymes are generally well tolerated, but some people may experience digestive upset or allergic reactions. Rare occupational exposure to powdered protease or phytase has triggered asthma and other allergic responses; typical oral use carries much lower risk. Premature infants given certain lipase products have occasionally experienced serious gastrointestinal effects, but this product is not intended for infants.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ET-Zymes Complete is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ET-Zymes Complete label
Sources

Sources & How We Checked

ET-Zymes Complete's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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