ExtenZe Extended Release By ExtenZe Overview & Drug Interactions

Supplement: ExtenZe Extended Release by ExtenZe

This product contains

• Yohimbe Bark Extract

  Description:

  Yohimbe is an evergreen tree native to western Africa. The bark of the tree contains a chemical called yohimbine in concentrations ranging from 0.6-1.38%, which has been used in traditional medicine as a natural aphrodisiac and sexual performance enhancer. While widely available as a dietary supplement, yohimbe should be used with caution, as it can have side effects, such as dizziness, increased blood pressure and rapid heart rate.

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  Ingredient Group	Yohimbe
  Category	botanical

  
  

  Dehydroepiandrosterone

  Description:

  Dehydroepiandrosterone (DHEA) is a natural (i.e., endogenous) hormone produced by the adrenal gland and is among the most abundant steroid hormones in the human body. It is a precursor to the hormones testosterone and estrogen, and it is thought to have various effects on the body. DHEA levels naturally decline with age. It is a popular over the counter supplement that is purported to have a variety of health benefits, including increasing muscle mass, improving cognitive function, improving mood and reducing the risk of heart disease and diabetes. The scientific evidence supporting the use of DHEA for these purposes is limited and mixed. Additionally, it could potentially interact with several different medications so if you are considering taking DHEA supplements, it is important to speak with a healthcare professional. DHEA should not be confused with other supplements containing the letters 'DHEA'. 7-alpha-hydroxy-DHEA, 7-beta-hydroxy-DHEA, and 7-keto-DHEA, all contain DHEA as the parent compound with additional structures attached.

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  Ingredient Group	DHEA
  Category	hormone

  
  

  Gamma-Aminobutyric Acid

  Description:

  Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter that is involved in a variety of functions, including regulating brain activity and behavior, relaxation, and sleep. GABA is endogenously produced in the brain from the amino acid glutamate and is responsible for inhibiting the activity of nerve cells in the brain and central nervous system. GABA is a popular dietary supplement and is used to help reduce anxiety and improve sleep, but more research is needed to determine its safety and effectiveness.

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  Ingredient Group	GABA
  Category	non-nutrient/non-botanical

  
  

  Niacin

  Description:

  Niacin, also known as vitamin B3, is a water-soluble vitamin found in a variety of foods, including meat, poultry, fish, and fortified grains. It plays a variety of roles in the body, including in the metabolism of carbohydrates, fats, and proteins. It is also necessary for the production of energy in the body and in the synthesis of different hormones. Niacin deficiency is rare in developed countries, however, supplementation has been shown to have several positive benefits. For example, it can reduce the risk of diabetic neuropathy (i.e., nerve pain) and has been shown effective for treating some types of high cholesterol (extended-release niacin is used as a prescription drug in the United States for this purpose). There is a multitude of niacin forms available as dietary supplements, including NADH, niacinamide, and nicotinamide riboside, all with different properties.

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  Ingredient Group	Niacin
  Category	vitamin

  
  

  Velvet Bean seed extract

  Ingredient Group	Cowhage
  Category	botanical

  
  

  Tongkat Ali root extract

  Description:

  Eurycoma longifolia, also known as tongkat ali or "Malaysian ginseng," is a plant native to Southeast Asia. It is a member of the Simaroubaceae family and is known for its small, yellow flowers and elongated, slender leaves. It has a long history of use in traditional medicine and is thought to have anti-inflammatory and pain-relieving effects. Eurycoma longifolia is also purported to have a number of other medicinal properties, including the ability to improve immune function, reduce the risk of heart disease, and lower cholesterol levels. Additionally, Eurycoma longifolia is commonly used as a natural treatment for male infertility and as a natural performance-enhancing supplement as it may have a mild androgenic effect. When used for male enhancement, it is most often marketed under other common names for the plant (e.g., tongkat ali, longjack).

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  Ingredient Group	Eurycoma Longifolia
  Category	botanical

  
  

  Tribulus fruit extract

  Description:

  Tribulus is a plant that belongs to the Zygophyllaceae family. It is native to a variety of warm and tropical regions of the world, including Africa, Asia, Europe, and Australia. The plant is known for its spiky, star-shaped flowers and hairy fruit, which contains small, hard seeds. Tribulus is often utilized as an ingredient in dietary supplements and is one of the most commonly used natural medicines in the world. Its most well-known use is as an aphrodisiac, with a purported ability to improve libido and sexual function. It has also been used to boost athletic performance, and reduce inflammation. Most often, it is the leaf, fruit, and root of Tribulus that are used as natural medicine. They contain a number of compounds, including protodioscin, which may influence certain hormones, such as testosterone and dehydroepiandrosterone.

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  Ingredient Group	Tribulus
  Category	botanical

  
  

• Black Pepper Fruit Extract

  Description:

  Black pepper is a spice made from the dried, unripe fruit of the Piper nigrum plant, which is native to the southwestern coast of India. It is one of the most widely used spices in the world, and it is often utilized to add flavor and heat to a wide variety of dishes. In traditional medicine, black pepper is purported to have a number of health benefits. It is a good source of antioxidants and is thought to have anti-inflammatory properties, which may make it useful in reducing inflammation and swelling in the body. Black pepper is also used as a natural remedy for digestive problems, such as indigestion and bloating, and to boost the immune system. Black pepper is widely used in dietary supplements, specifically, an extract from black pepper known as piperine. Piperine can affect the absorption of many drugs, which is why it has a large number of reported interactions. Oftentimes, these 'interactions' are purposeful, such as when piperine is used with turmeric, to increase its absorption.

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  Ingredient Group	Black Pepper
  Category	botanical

  
  

  Cnidium seed extract

  Description:

  Cnidium is a plant that is native to China and other parts of Asia and a member of the umbelliferae family, which includes a variety of plants such as parsley, fennel, and dill. Cnidium is known for its medicinal properties and is commonly used in traditional Chinese medicine to treat a variety of conditions, including skin infections, dermatitis, asthma, and erectile dysfunction. It has also been used as a source of antioxidants as well as to increase athletic performance.

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  Ingredient Group	Cnidium
  Category	botanical

  
  

  Damiana leaf extract

  Description:

  Damiana (Turnera diffusa) is a small, aromatic shrub native to Central and South America, known for its historical use in traditional medicine and as an aphrodisiac. The plant produces small, yellow flowers and has a long history of traditional use among indigenous peoples. Damiana leaves are commonly dried and brewed as an herbal tea, believed to have mild stimulant and relaxant properties.

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  Ingredient Group	Damiana
  Category	botanical

  
  

  Asian Ginseng

  Ingredient Group	Oriental Ginseng
  Category	botanical

  
  

  Barrenwort leaf extract

  Ingredient Group	Epimedium
  Category	botanical

  
  

  L-Arginine

  Ingredient Group	Arginine
  Category	amino acid

  
  

  Licorice Root Extract

  Description:

  Licorice, also known as glycyrrhiza, is a plant native to parts of Europe, Asia, and the Mediterranean region. The root of the plant has been used for centuries in traditional medicine and is often consumed in the form of candy, tea, and supplements. Licorice has a number of purported health benefits, including the ability to soothe sore throats, reduce inflammation, and improve digestive problems. It may also have antiviral and antibacterial properties. Licorice naturally contains glycyrrhizin, or glycyrrhizic acid, which can have toxic effects if consumed in large amounts. However, licorice can be processed to remove glycyrrhizin, resulting in DGL (deglycyrrhizinated licorice). Many dietary supplements that contain deglycyrrhizinated licorice are often simply named 'DGL'.

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  Ingredient Group	Licorice
  Category	botanical

  
  

  Muira Puama Bark Extract

  Ingredient Group	Muira Puama
  Category	botanical

  
  

  Pregnenolone

  Description:

  Pregnenolone is a hormone that is produced naturally in the body by the adrenal glands as well as in the brain. It is a precursor to other hormones, including cortisol, progesterone, testosterone, dehydroepiandrosterone (DHEA), and estrogens, and plays a role in a number of bodily functions. Pregnenolone is often utilized as a dietary supplement and is purported to have a number of potential health benefits, including improved memory and cognitive function, reduced anxiety and stress, and enhanced immune function. Pregnenolone is also used for its supposed anti-aging properties.

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  Ingredient Group	Pregnenolone
  Category	hormone

  
  

  Folate

  Ingredient Group	Folate
  Category	vitamin

  Forms

  • Folic Acid

  
  

  Yohimbine Hydrochloride

  Ingredient Group	Yohimbine
  Category	non-nutrient/non-botanical

  
  

  Astragalus Root Extract

  Description:

  Astragalus is a genus of plants native to Asia and Northern Africa, and is known for its small, yellow or purple flowers and its long, tapering root. In traditional medicine, astragalus has been used to boost the immune system and treat a variety of conditions, including colds, flu, and upper respiratory infections. It is commonly referred to as an 'adaptogen', which are theorized to help the body resist stress.

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  Ingredient Group	Astragalus
  Category	botanical

  
  

  Chrysin

  Ingredient Group	Chrysin
  Category	non-nutrient/non-botanical

  
  

Drugs that interact with ExtenZe Extended Release by ExtenZe