Extra-Strength ibuActin PM By Solaray Overview & Drug Interactions

Hops are the female flowers (also known as cones) of the hop plant, Humulus lupulus, and a member of the Cannabaceae family. Hops are native to Europe and are widely cultivated in many parts of the world. Hops have a variety of applications, such as for food flavoring and brewing beer. Hops extract has been used in topical medicinal preparations and as a dietary supplement.

Bromelain is a group of proteolytic enzymes derived from pineapples. It has been traditionally used for its anti-inflammatory and protein-digesting properties. Some research suggests it may have potential benefits for conditions such as allergic rhinitis, burns, cancer, diabetic foot ulcers, and postoperative pain, among others. However, the evidence for its effectiveness in these areas is lacking, and more research is needed. It is important to note that bromelain should not be confused with other protein-digesting enzymes. Pregnant and lactating individuals should avoid using bromelain due to insufficient information about its safety in these populations.

Passionflower (Passiflora incarnata) is a climbing vine with fragrant white and purple flowers that is native to the Americas. It is purported to have a number of potential health benefits, including reducing anxiety and improving sleep. It is thought to work by increasing the levels of GABA (gamma-aminobutyric acid), a neurotransmitter in the brain that helps regulate mood and anxiety. Passionflower may also have mild sedative and muscle-relaxing effects and may be helpful in the treatment of muscle spasms and other muscle disorders. Dietary supplements containing passionflower are generally standardized to contain no less than 1.5% of the flavanoid vitexin.

Eleuthero (Eleutherococcus senticosus) is a plant native to Asia and a member of the Araliaceae family. It is also commonly known as 'Siberian ginseng' or 'eleuthero root'. The root of the plant is used in traditional medicine for its purported ability to improve physical and mental performance, boost the immune system, and reduce fatigue. It is also claimed to have anti-inflammatory and antioxidant properties. Eleuthero is often referred to as an 'adaptogen'. Adaptogens are believed to help the body resist stress. It is important to note that although eleuthero is known as 'Siberian ginseng', it is not related to Panax ginseng.

Theanine, often referred to as L-theanine as that is the predominant isomer of theanine, is an amino acid commonly found in tea leaves, particularly in green tea. It is purported to increase levels of GABA, serotonin, and dopamine in the brain, which can help to reduce stress and anxiety. L-theanine may also promote a sense of calm and improve overall well-being. Some studies have also suggested that it may improve cognitive function, although more research is needed. Most reported drug interactions with theanine are due to its sedative effects.

Papain is a proteolytic enzyme that is extracted from the papaya fruit. It is also known as papaya proteinase. Proteolytic enzymes are enzymes that break down proteins into smaller peptides and amino acids. Papain specifically breaks down proteins by hydrolyzing the peptide bonds that link amino acids together. Papain is used in a variety of applications, including food production, medicine, and biotechnology. Medically, papain can be used to remove dead tissue from wounds and to treat certain skin conditions. It has also been used to treat sports injuries, such as sprains and strains. Additionally, it is a common ingredient in digestive enzyme dietary supplements to aid in the digestion of proteins.

Ginger is a spice native to Asia and part of the Zingiberaceae family. It has a pungent, spicy flavor and is often used to add flavor to dishes and drinks. Ginger has a long history of use in traditional medicine and is believed to have anti-inflammatory, antioxidant, and other medicinal properties. It is commonly used to treat nausea, motion sickness, and other digestive issues. Ginger is also sometimes used to relieve pain and reduce inflammation. Ginger supplements generally standardize several compounds found in the root, and are often labeled as containing a certain amount of 'ginger root extract'.

Turmeric is a commonly used spice and a member of the ginger family (Zingiberaceae). It is native to India and other parts of South Asia and is known for its bright orange-yellow color and its warm, slightly bitter flavor. In traditional medicine, turmeric is believed to have a number of health benefits due to its high content of antioxidants and other compounds, such as curcumin. It is thought to have anti-inflammatory and antimicrobial properties, and it is often used to treat a variety of conditions, including joint pain, digestive problems, skin disorders, and respiratory infections. Most dietary supplements that utilize turmeric standardize their products based on a specific amount of curcumin (curcuminoids) per dose. Additionally, turmeric supplements are often paired with black pepper extract (piperine) to improve oral absorption.

Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter that is involved in a variety of functions, including regulating brain activity and behavior, relaxation, and sleep. GABA is endogenously produced in the brain from the amino acid glutamate and is responsible for inhibiting the activity of nerve cells in the brain and central nervous system. GABA is a popular dietary supplement and is used to help reduce anxiety and improve sleep, but more research is needed to determine its safety and effectiveness.

Melatonin is a hormone that is produced naturally in the pineal gland. It is involved in several different bodily processes, such as the regulation of the body's sleep-wake cycle. Melatonin is available as a dietary supplement and is often used to help people with sleep disorders, such as insomnia, fall asleep more easily. There is some evidence to suggest that melatonin supplements may be helpful in reducing the time it takes to fall asleep and improving sleep quality, although the results of studies on this topic have been mixed. Studies show better support for some specific conditions, such as Delayed sleep phase syndrome (DSPS) and Non-24-hour sleep-wake disorder. Melatonin is generally considered to be safe when used in the short term, although it can cause side effects in some people, such as dizziness, headache, and nausea. While melatonin is a natural hormone, it is often synthesized for its use in dietary supplements.