Extra Strength Lutein 20 mg Ingredients & Drug Interactions
by Nature Made
What is this page for?
First and foremost: checking Extra Strength Lutein 20 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Extra Strength Lutein 20 mg is a dietary supplement by Nature Made with 1 active ingredient. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Extra Strength Lutein 20 mg by Nature Made
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This softgel contains one active ingredient: lutein, a yellow pigment found naturally in leafy greens and other plants. Your body stores it mainly in the eyes, where it's believed to protect the tissue from damage.
Each softgel delivers 20 mg — a stronger dose than what you'd typically get from food alone. The softgel itself is made with corn oil, gelatin, glycerin, water, and artificial colors to hold everything together and keep it stable.
Does it work?
Moderate evidence
Lutein is possibly effective for slowing age-related macular degeneration (AMD) and cataracts — the two eye conditions where the evidence is strongest. For other conditions like retinitis pigmentosa, retinopathy of prematurity, bronchopulmonary dysplasia, and necrotizing enterocolitis, the research suggests it probably doesn't work.
The bottom line: if AMD or cataract risk is your concern, there's reason to think this could help, but the science isn't airtight yet.
How safe is it?
Well-documented data
Lutein from food and typical supplement doses is generally well tolerated — clinical trials at 20 mg daily haven't shown adverse effects. That said, there isn't enough research on the safety of high supplement doses in pregnancy and breastfeeding, even though lutein naturally appears in breast milk.
The safety data does rate it as likely safe in pregnancy and lactation, but the caution is worth knowing: if you're pregnant or nursing, it's wise to talk with your doctor or pharmacist before adding this to see if it makes sense for you personally.
Meds to double-check
No known interactions
No interactions are documented for the ingredients we could check. Still, run your exact medications through the search tool on this page just to be thorough — it only takes a moment.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
If you're concerned about age-related macular degeneration or cataracts and want a well-tolerated option with some research backing it, this is worth considering. It's not a magic fix, and it won't help every eye condition — but the evidence for AMD and cataract support is real.
Check with your own doctor or pharmacist first, especially if you're pregnant, nursing, or managing other health conditions.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Extra Strength Lutein 20 mg, straight from the product label.
| Brand | Nature Made |
|---|---|
| Barcode (UPC) | 031604010690 |
| Net contents | 30 Liquid Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Nov 25, 2013 |
| DSLD ID | 27707 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Qualified Health, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Extra Strength Lutein 20 mg by Nature Made, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lutein | 20 mg | -- |
Other ingredients: Corn Oil, Gelatin, Glycerin, Water, Artificial Colors
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Lutein liquid softgels are made to Nature Made's guaranteed purity and potency standards. Valid only for U.S. and Puerto Rico residents.
Clinical studies indicate that Lutein is beneficial in maintaining Eye Health & Healthy Vision. Lutein helps maintain macular pigment density which is essential for optimal vision. Nature Made's Lutein source is the only free lutein ingredient that has been shown through published studies to increase macular pigment optical density.
Enter Code for Wellness Rewards Points at www.NatureMade.com
Clinically Proven for Healthy Vision
Formulation
No Artificial Flavors - No Preservatives - No Yeast, Starch or Gluten
Storage
Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.
Precautions
Store in a cool, dry place, out of reach of children.
Do not use if imprinted seal under cap is broken or missing.
Suggested/Recommended/Usage/Directions
SUGGESTED USE: Take one softgel daily with a meal.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
List No. 1069 L34 Cat. 985 5A004
Seals/Symbols
{Drop}(R)
FDA Statement of Identity
DIETARY SUPPLEMENT
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Extra Strength Lutein 20 mg by Nature Made label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Extra Strength Lutein 20 mg by Nature Made
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Lutein
No knowninteractions
Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...
Lutein monograph & interactionsOther (inactive) ingredients: Corn Oil, Gelatin, Glycerin, Water, Artificial Colors. These complete the product’s ingredient list but are not active constituents.
Extra Strength Lutein 20 mg by Nature Made Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Extra Strength Lutein 20 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Extra Strength Lutein 20 mg, from the product label.
Nature Made
See all Nature Made products- Name
- Nature Made Nutritional Products
- City
- Mission Hills
- State
- CA
- ZipCode
- 91346-9606
- Phone Number
- 1-800-276-2878
- Web Address
- www.NatureMade.com
Extra Strength Lutein 20 mg by Nature Made: Common Questions
Does Extra Strength Lutein 20 mg by Nature Made interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does lutein actually prevent or reverse vision loss?
Is it safe to take while pregnant or breastfeeding?
What's the difference between getting lutein from food and from this supplement?
Are there any side effects at the 20 mg dose?
Can I take this with my other medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Extra Strength Lutein 20 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Extra Strength Lutein 20 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Extra Strength Lutein 20 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 2 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lutein 2 references
- Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
- Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC