Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Formula 899 Ingredients & Drug Interactions

by DC

Formula 899 label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Formula 899 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Formula 899 is a dietary supplement by DC with 2 active ingredients. Its ingredients are commonly taken for menopausal symptoms, menstrual cramps, hormone balance (popular belief).Based on those ingredients, 41 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Mexican Yam extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Formula 899 by DC

Ask about any prescription or over-the-counter medication and we check it for interactions with Formula 899 by DC — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Formula 899 by DC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Formula 899 contains 2 active ingredients: adrenal concentrate and Mexican Yam extract (from Wild Yam). The adrenal concentrate is a glandular ingredient intended to support adrenal function, while Mexican Yam extract is traditionally used for menopausal and hormonal support.

The capsule also contains several inactive ingredients — gelatin, vegetable cellulose, vegetable magnesium stearate, and silica — which are binding and filling materials.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: hormone balance and menopausal symptom support.
  • We looked for evidence on: Menopausal symptoms, Postmenopausal conditions, Dysmenorrhea, Premenstrual syndrome (PMS), hormonal balance, women's health — and 1 related terms.
  • The closest evidence on file: Wild Yam is rated "Possibly Ineffective" for Menopausal symptoms (Natural Medicines).
  • Also on file: Wild Yam is rated "Insufficient Reliable Evidence To Rate" for Postmenopausal conditions, Premenstrual syndrome (PMS), Dysmenorrhea.

The evidence for Mexican Yam extract is limited. For menopausal symptoms, the data suggests it's possibly ineffective — meaning trials haven't shown strong benefit.

For gallbladder disease, sexual dysfunction, irregular periods, and infertility, there isn't enough reliable evidence to rate whether it works. We hold no effectiveness data for the adrenal concentrate ingredient.

The evidence, ingredient by ingredient Wild Yam

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mexican Yam extract is generally well tolerated in the short term for healthy adults, but long-term safety hasn't been well studied. Common side effects can include fever, headache, upset stomach, and vomiting, especially at higher doses.

Anaphylaxis (a severe allergic reaction) is rare but possible. There isn't enough safety data to recommend this product during pregnancy or while breastfeeding — talk with your doctor or pharmacist about what's right for you in those situations.

Side effects, ingredient by ingredient Wild Yam

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wild Yam.
  • The most serious interaction on file is rated Moderate.
  • For scale: 41 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking Formula 899 if you're on estrogen-based medications — including birth control pills, hormone replacement therapy, or estrogen patches. The Mexican Yam extract in this product could theoretically increase or decrease estrogen's effects.

We couldn't check the adrenal concentrate for interactions either, so run all your prescriptions through the tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Formula 899 may appeal to you if you're exploring traditional support for adrenal and hormonal function, but the evidence for Mexican Yam extract's effectiveness is weak or absent. If you're on estrogen-based medications or hormone therapy, check with your doctor or pharmacist before taking it — the extract could interfere with how your medications work.

Long-term safety data is limited, so this isn't a long-term supplement without professional guidance.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Formula 899, straight from the product label.

Brand DC
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2022
DSLD ID 265786
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Formula 899 by DC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
IngredientAmount% DV
Adrenal concentrate100 mg--
Mexican Yam extract300 mg--

Other ingredients: Gelatin, Vegetable Cellulose, Vegetable Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Guaranteed Maximum Potency Mexican Yam Root Extract contains the highest quality, most potent form of Mexican Yam Root Extract available. An abundant source of Diosgenin, a DHEA precursor. Mexican Yam Root Extract is concentrated and standardized then blended with Premium Wildcrafted Mexican Yam Root Powder and Adrenal concentrate to contain the greatest concentration of naturally balanced active ingredients. This process retains and enhances all the whole plant's synergistic benefits.

Mexican yam root standardized for 30,000 mcg diosgenin

Formulation

FDA Registered Facility (Reg. #1023013) Mfg. under Good Manufacturing Practices (GMPs) Made in USA

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Gluten free

Made in USA

Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

General Statements

The names Mexican Yam root and Wild Yam root are interchangeable.

Seals/Symbols

Quali Pure

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 capsule twice daily, preferably with morning and evening meals.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Formula 899 by DC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Formula 899 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Formula 899 by DC

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Adrenal concentrate

100 mg per serving

Mexican Yam extract

Interacts with
41 drugs
300 mg per serving

Wild yam is a root traditionally used for menopausal symptoms, cramps, and as a so-called 'natural' hormone supplement, but solid human evidence for t...

Mexican Yam extract monograph & interactions

Other (inactive) ingredients: Gelatin, Vegetable Cellulose, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Formula 899 by DC Drug Interactions

Want to check YOUR meds against Formula 899?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
41Drugs
41 Moderate

Ingredients driving the most interactions

Mexican Yam extract 41

Individual Drug Interactions

The ingredients in Formula 899 interact with 41 drugs. Click any drug to see the details.

1 of the 2 ingredients in Formula 899 interact with drugs. Each result below shows which ingredient is responsible. Mexican Yam extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Formula 899 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Mexican Yam extract1 drug type · 41 drugs

Estrogens

Theoretically, wild yam might increase or decrease the effects of estrogen.
Wild yam root shows estrogenic and anti-estrogenic effects in vitro. Theoretically, wild yam might interfere with hormone therapy.

Likelihood Possible Evidence D
Mexican Yam extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Formula 899, from the product label.

DC

See all DC products
Name
Dee Cee Laboratories, Inc.
Street Address
304 Dee Cee Ct.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

Formula 899 by DC: Common Questions

Does Formula 899 by DC interact with any medications?
Yes. Based on its ingredients, Formula 899 has a known interaction with 41 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Formula 899 contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product work for menopause?
The data suggests Mexican Yam extract is possibly ineffective for menopausal symptoms. There's not strong evidence behind it for hot flashes or other menopause-related complaints.
Can I take this while on birth control?
Not without checking with your doctor first. Mexican Yam extract can theoretically interfere with how estrogen works, which means it might affect how your birth control functions. Your doctor or pharmacist can advise you based on your specific medication.
Is it safe to take long-term?
Short-term use in healthy adults appears generally fine, but long-term safety hasn't been well studied. If you're thinking about taking this regularly, talk it over with your doctor or pharmacist.
What are the side effects?
Most common ones are fever, headache, upset stomach, and vomiting — especially at higher doses. Severe allergic reaction (anaphylaxis) is rare but possible.
Can I take this while pregnant or breastfeeding?
There isn't enough safety data to know. Avoid it during pregnancy and while breastfeeding unless your doctor says otherwise — talk with them about whether it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Formula 899 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Formula 899 label
Go deeper

The Full Monographs Behind Formula 899’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wild Yam

Interacts with 41 drugs

Wild yam is a root traditionally used for menopausal symptoms, cramps, and as a so-called 'natural' hormone supplement, but solid human evidence for these uses is lacking. Despite popular cl...

Read the full Wild Yam monograph →
Sources

Sources & How We Checked

Formula 899's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wild Yam 7 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
  3. Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
  4. Rosenberg Zand, R. S., Jenkins, D. J., and Diamandis, E. P. Effects of natural products and nutraceuticals on steroid hormone-regulated gene expression. Clin Chim.Acta 2001;312(1-2):213-219. PubMed
  5. Araghiniknam M, Chung S, Nelson-White T, and et al. Antioxidant activity of Dioscorea and dehydroepiandrosterone (DHEA) in older humans. Life Sciences 1996;59:L147-L157.
  6. Zeng M, Zhang L, Li M, et al. Estrogenic effects of the extracts from the Chinese Yam (Dioscorea opposite Thunb.) and its effective compounds in vitro and in vivo. Molecules. 2018 Jan 23;23(2). Pii: E11. PubMed
  7. Lu J, Wong RN, Zhang L, et al. Comparative analysis of proteins with stimulating activity on ovarian estradiol biosynthesis from four different Dioscorea species in vitro using both phenotypic and target-based approaches: implication for treating menopaus

See these in context on the Wild Yam monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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