No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 10 ingredients. Check your meds →
Dietary supplement

GLTN Ingredients & Drug Interactions

by Loomis Enzymes

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

GLTN is a dietary supplement by Loomis Enzymes with 10 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of GLTN by Loomis Enzymes

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 10 active ingredients.
  • “Proprietary Enzyme Blend” is a proprietary blend — the label gives one combined amount (139 mg) without saying how much of each component you get.

GLTN is a multi-enzyme supplement with 10 active ingredients designed to support digestion. The product contains Lipase (a fat-digesting enzyme), Lactase (breaks down milk sugar), and Cellulase, Invertase, Glucoamylase, Hemicellulase, and Diastase — all carbohydrate-digesting enzymes.

It also includes a Proprietary Enzyme Blend, Tolerase G, and BioCore DPP-IV. The capsule also contains inactive ingredients including cellulose, water, and phytase.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Lactose intolerance — rated "Effective" (Lactase) (Natural Medicines).

Lactase is effective for lactose intolerance — if you have trouble digesting dairy, it can help. For the other enzymes in this product, the evidence we hold is insufficient to rate how well they work for dyspepsia (indigestion) or inflammatory bowel disease (IBD).

We don't have effectiveness data on file for Lipase, Amylase, Cellulase, Invertase, Glucoamylase, Hemicellulase, Diastase, Tolerase G, or BioCore DPP-IV.

The evidence, ingredient by ingredient Lipase Lactase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase is generally well tolerated in supplement form, though people with serious digestive conditions should use it only under medical guidance. Lactase is generally well tolerated when used as directed.

Both have limited pregnancy and breastfeeding safety data — there isn't enough evidence to know either way, so talk with your doctor or pharmacist if you're pregnant or nursing before taking this regularly. A rare case of allergic reaction (contact dermatitis and allergic rhinoconjunctivitis) to lactase has been reported in someone handling powdered lactase, though it's uncommon.

Side effects, ingredient by ingredient Lipase Lactase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, ask your pharmacist to run your exact medications against this product before you take it.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

This product is a broad-spectrum digestive enzyme blend — especially useful if you're lactose intolerant. Since most ingredients haven't been thoroughly tested against medications, talk with your pharmacist before starting it if you take any prescriptions.

It's generally well tolerated, but people with serious digestive conditions should check with their doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about GLTN, straight from the product label.

Brand Loomis Enzymes
Barcode (UPC) 697706014006
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 306283
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for GLTN by Loomis Enzymes, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
697706014006
IngredientAmount% DV
Amylase0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Invertase0 NP--
Glucoamylase0 NP--
Hemicellulase0 NP--
Diastase0 NP--
Proprietary Enzyme Blend139 mg--
Tolerase G345 mg--
BioCore DPP-IV160 mg--

Other ingredients: Cellulose, Water, Phytase

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of reach of children.

Note: Consult your physician before using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Do not use if inner or outer seal is broken, torn, or missing.

Notice: Tolerase G is not intended to replace a gluten-free diet. Tolerase G is not intended to treat or prevent celiac disease.

Storage

To ensure freshness and potency, keep bottle tightly closed and store in a cool, dry place.

FDA Statement of Identity

A Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions for use: Take 2 capsules with each meal or as directed by your healthcare practitioner.

Brand IP Statement(s)

Tolerase G is a registered trademark of DSM

BioCore DPP-IV is a registered trademark of Deerland Probiotics and Enzymes

See for yourself

GLTN by Loomis Enzymes label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in GLTN by Loomis Enzymes

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Enzyme Blend

139 mg per serving
  • › Amylase
  • Lipase
  • Lactase
  • › Cellulase
  • › Invertase
  • › Glucoamylase
  • › Hemicellulase
  • › Diastase

Tolerase G

345 mg per serving Form: Prolyl Endopeptidase

BioCore DPP-IV

160 mg per serving Form: Protease, Protease, Protease

Other (inactive) ingredients: Cellulose, Water, Phytase. These complete the product’s ingredient list but are not active constituents.

Interaction report

GLTN by Loomis Enzymes Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in GLTN. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for GLTN, from the product label.

Loomis Enzymes

See all Loomis Enzymes products
Name
Loomis Enzymes, LLC
City
Fitchburg
State
Wisconsin
ZipCode
53719
Phone Number
1-800-614-4400
Web Address
www.loomisenzymes.com
Pharmacist Counseling Corner

GLTN by Loomis Enzymes: Common Questions

Does GLTN by Loomis Enzymes interact with any medications?
We do not currently list a known interaction for the mapped ingredients in GLTN. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
GLTN contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this work for lactose intolerance?
Yes — lactase, one of the enzymes in this product, is effective for lactose intolerance. It helps you digest milk sugar if your body doesn't make enough of its own lactase enzyme.
Is it safe to take while pregnant?
The safety data on Lipase during pregnancy is limited, so use it only if your doctor advises it. Lactase is likely safe in pregnancy, but check with your doctor first. There isn't enough data on the other ingredients.
What if I'm breastfeeding?
Lactase has limited breastfeeding data but acts only in the gut, so ask your doctor or pharmacist first. Lipase safety while breastfeeding hasn't been well studied — check with your healthcare provider.
What's this product supposed to do?
It's a digestive enzyme blend meant to support digestion of fats, carbohydrates, and milk sugar. Lactase specifically helps if you're lactose intolerant.
Are there any side effects?
No adverse effects have been reported in adults with these enzymes in supplement form. A rare allergic reaction to lactase (contact dermatitis or allergic rhinitis) has been reported in occupational settings, but it's uncommon.
Can I take this if I have digestive problems?
Lactase works well for lactose intolerance. For other digestive conditions, the evidence for the other enzymes isn't established. If you have serious digestive disease, use this only under medical guidance.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if GLTN is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

GLTN label
Sources

Sources & How We Checked

GLTN's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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