Glycine Powder Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Glycine Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Glycine Powder is a dietary supplement by Vital Nutrients with 1 active ingredient. Its ingredients are commonly taken for sleep quality and insomnia, relaxation, cognitive function.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glycine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Glycine Powder by Vital Nutrients
Ask about any prescription or over-the-counter medication and we check it for interactions with Glycine Powder by Vital Nutrients — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Glycine Powder by Vital Nutrients
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Vital Nutrients Glycine Powder contains one active ingredient: glycine, a simple amino acid your body makes naturally and uses to build proteins and support nervous system function. This product is just glycine — there are no other active ingredients or fillers listed.
Does it work?
Moderate evidence
Glycine is possibly effective for schizophrenia based on the evidence we hold. For other uses—including 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency, attention deficit-hyperactivity disorder (ADHD), benign prostatic hyperplasia (BPH), and cystic fibrosis—the evidence isn't established enough to rate it, which means either studies are too small or conflicting, or data is sparse.
How safe is it?
Well-documented data
Glycine is generally well tolerated at typical doses, but long-term safety data are limited. Mild sedation has occurred rarely; a small number of people report irritability, insomnia, fatigue, memory trouble, headache, or sensory changes, though a clear link to glycine isn't proven.
Digestive upset—soft stools, nausea, vomiting, stomach discomfort, or dry mouth—happens rarely and clears quickly when you stop taking it. Not enough reliable safety data exists for pregnancy or while breastfeeding, so caution is advised.
Talk with your doctor or pharmacist before taking this supplement if you're pregnant, planning pregnancy, or nursing.
Meds to double-check
Moderate interaction found
If you take clozapine (Clozaril) for schizophrenia, check with your doctor or pharmacist before adding this supplement—glycine may reduce how well it works. No other drug interactions are documented in our data for the ingredients we could check.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Glycine Powder may be worth considering if you have schizophrenia and want to explore options beyond medication alone, though evidence is limited. If you take clozapine, you need to check with your doctor or pharmacist first—the interaction matters.
For other uses, evidence isn't strong enough to support it yet. Talk it over with your own healthcare provider before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Glycine Powder, straight from the product label.
| Brand | Vital Nutrients |
|---|---|
| Barcode (UPC) | 693465111116 |
| Net contents | 250 Gram(s); 8.82 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Jan 24, 2024 |
| DSLD ID | 305046 |
| Product type | Amino Acid/protein |
| Supplement form | Powder |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Glycine Powder by Vital Nutrients, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Glycine | 4000 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Store sealed in a cool dry place
Precautions
Keep out of reach of children
Use only if safety seal is intact
Warning: If pregnant, consult your physician before taking.
Inner seal may lift off when cap is removed. Seal integrity is maintained until cap is removed.
Suggested/Recommended/Usage/Directions
Recommendations: One-half to one rounded teaspoon 1 to 3 times daily, dissolved in water, in between or with meals, or as directed by your healthcare professional.
Formulation
Excludes: Coatings, binders, gluten (wheat, rye barley), milk/dairy (Casein, whey), soy protein, egg protein, sugar. Verified by independent testing.
Raw materials and finished products are independently tested by U.S. Labs. Learn more at vitalnutrients.net
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Glycine Powder by Vital Nutrients label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Glycine Powder by Vital Nutrients
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Gram(s) Dosage formPowder Servings per container63 Amounts shown are per serving.
Glycine
Interacts with1 drug
Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...
Glycine monograph & interactionsGlycine Powder by Vital Nutrients Drug Interactions
HelloPharmacist Interaction Report
Vital Nutrients Glycine Powder has one documented interaction: glycine may decrease how well clozapine (Clozaril) works for schizophrenia.
One small study found that adding glycine to clozapine actually worsened schizophrenia symptoms compared to clozapine alone, though researchers don't yet understand exactly why this happens.
Read the full breakdown — every affected drug type, severity by severity
If you take clozapine, check with your doctor or pharmacist before starting this supplement. The interaction is moderate in severity, meaning the effect matters clinically but isn't an emergency.
Altogether, these interactions span 1 individual medication.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Glycine Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Glycine Powder interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in Glycine Powder interact with drugs. Each result below shows which ingredient is responsible. Glycine
ClozapineClozaril, Versacloz
How Clozapine interacts with Glycine Powder — through 1 ingredient. Tap an ingredient for the detail:
GlycineClozapine (clozaril) Moderate
Interaction Summary
Theoretically, glycine might decrease the effectiveness of clozapine.
Read the full Glycine + Clozapine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Glycine Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Glycine
Clozapine (Clozaril)
Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.
Brand information
Manufacturer and brand details for Glycine Powder, from the product label.
Vital Nutrients
See all Vital Nutrients products- Name
- Vital Nutrients
- Street Address
- 45 Kenneth Dooley Dr
- City
- Middletown
- State
- CT
- ZipCode
- 06457
- Web Address
- vitalnutrients.net
Glycine Powder by Vital Nutrients: Common Questions
Does Glycine Powder by Vital Nutrients interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does glycine actually help schizophrenia?
What side effects might I notice?
Can I take this while pregnant or breastfeeding?
Is this safe to take long-term?
What is glycine and what does it do in my body?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Glycine Powder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Glycine Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Glycine Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Glycine 5 references
- Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
- Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
- Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
- Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
- Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC