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Dietary supplement

Glycine Sticks 3 grams Ingredients & Drug Interactions

by Metabolic Maintenance

Powder Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Glycine Sticks 3 grams is a dietary supplement by Metabolic Maintenance with 1 active ingredient. Its ingredients are commonly taken for sleep quality and insomnia, relaxation, cognitive function.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glycine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Glycine Sticks 3 grams by Metabolic Maintenance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: glycine, a simple amino acid. Each stick delivers 3 grams of glycine in powder form, with no inactive fillers or other ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glycine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Glycine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Schizophrenia — rated "Possibly Effective" (Natural Medicines).

Glycine is rated possibly effective for schizophrenia. For other conditions listed—3-phosphoglycerate dehydrogenase deficiency, ADHD, benign prostatic hyperplasia, and cystic fibrosis—the evidence we hold is insufficient to rate whether it works.

The evidence, ingredient by ingredient Glycine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glycine is generally well tolerated at typical doses, but long-term safety data are limited. A small number of trial participants reported mild sedation, though symptoms cleared quickly after stopping it.

Rarely, people have also reported irritability, insomnia, fatigue, memory problems, headache, and sensory changes, though whether glycine caused these isn't clear. Digestive side effects like soft stools, nausea, vomiting, and upper stomach discomfort have occurred rarely and resolved quickly; dry mouth has also been reported.

There isn't enough reliable safety data on glycine in pregnancy or while breastfeeding, so it's best avoided in these situations unless your doctor approves.

Side effects, ingredient by ingredient Glycine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glycine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take clozapine (Clozaril) for schizophrenia, check with your doctor or pharmacist before starting this product. Glycine may decrease how well clozapine works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Glycine may help with schizophrenia symptoms, though the evidence is still developing and long-term safety isn't fully established. If you take clozapine, talk with your doctor or pharmacist before trying this product—the interaction could affect how well your medication works.

For anyone else considering glycine, a conversation with your own healthcare provider about whether it fits your situation is a good idea.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glycine Sticks 3 grams, straight from the product label.

Brand Metabolic Maintenance
Barcode (UPC) 838287001256
Net contents 30 Stick(s)
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 274042
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glycine Sticks 3 grams by Metabolic Maintenance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Gram(s)
Maximum serving Sizes:
3 Gram(s)
Servings per container
30
UPC/BARCODE
838287001256
IngredientAmount% DV
Calories10 {Calories}--
Glycine3 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Caution: Pregnant or lactating women, consult your healthcare professional before taking this product.

Keep tightly closed in a cool, dry place, out of the reach of children.

Storage

Keep tightly closed in a cool, dry place, out of the reach of children.

Formulation

Egg free Gluten free Free of nuts Dairy free

Manufactured in a GMP Compliant Facility

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: One stick daily, or as directed by a healthcare professional. Pure Glycine Powder may be easily combined with water, fruit juice or other liquids.

See for yourself

Glycine Sticks 3 grams by Metabolic Maintenance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Glycine Sticks 3 grams by Metabolic Maintenance

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Glycine

Interacts with
1 drug
3 Gram(s) per serving

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...

Glycine monograph & interactions
Interaction report

Glycine Sticks 3 grams by Metabolic Maintenance Drug Interactions

Want to check YOUR meds against Glycine Sticks 3 grams?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Glycine Sticks 3 grams with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Glycine1 drug type · 1 drug

Clozapine (Clozaril)

Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.

Likelihood Probable Evidence B
The maker

Brand information

Manufacturer and brand details for Glycine Sticks 3 grams, from the product label.

Metabolic Maintenance

See all Metabolic Maintenance products
Name
Metabolic Maintenance
Street Address
601 N Larch Street
City
Sisters
State
Oregon
ZipCode
97759
Phone Number
800-772-7873
Web Address
MetabolicMaintenance.com
Pharmacist Counseling Corner

Glycine Sticks 3 grams by Metabolic Maintenance: Common Questions

Does Glycine Sticks 3 grams by Metabolic Maintenance interact with any medications?
Yes. Based on its ingredients, Glycine Sticks 3 grams has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glycine Sticks 3 grams contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is glycine safe to take while I'm pregnant or breastfeeding?
There isn't enough reliable safety data to know either way. Talk with your doctor or pharmacist before using glycine during pregnancy or while breastfeeding—they can help you decide what's best for you and your baby.
What does glycine do in the body?
Glycine is an amino acid your body uses naturally. This product is studied mainly for schizophrenia, where it's rated possibly effective, though long-term research is still limited.
Can glycine cause side effects?
Most people tolerate it well. Rarely, mild sedation, digestive upset (soft stools, nausea, vomiting, stomach discomfort), or dry mouth have been reported and cleared quickly when people stopped taking it. Other uncommon reports include irritability, insomnia, fatigue, memory problems, headache, and sensory changes, though a clear link to glycine isn't certain.
Why is it in powder form as sticks?
The product facts don't detail why this particular form was chosen—that's a question for the manufacturer or your pharmacist.
How much glycine does each stick contain?
Each stick provides 3 grams of glycine.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glycine Sticks 3 grams label
Go deeper

The Full Monographs Behind Glycine Sticks 3 grams’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Glycine Sticks 3 grams's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glycine 5 references
  1. Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
  2. Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
  3. Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
  4. Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
  5. Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed

See these in context on the Glycine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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