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Dietary supplement

Graviola 530 mg Ingredients & Drug Interactions

by Swanson

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Graviola 530 mg is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for cancer support (unproven), infections, inflammation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Graviola. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Graviola 530 mg by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: graviola (also called soursop), a tropical fruit extract at 530 mg per capsule. The inactive ingredients are gelatin, rice bran, rice extract blend, and silica — standard capsule fillers and binders.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: promotes calmness, relaxation and mood.
  • We looked for evidence on: anxiety, stress, depression, mood disorders.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence isn't established in our data. Graviola has been studied for human papillomavirus (HPV) infection, headache, insect repellent use, and male infertility, but all of these carry insufficient reliable evidence to rate its effectiveness.

If you're considering it for a specific concern, talk with your doctor about whether the science supports its use.

The evidence, ingredient by ingredient Graviola

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Regular use of graviola may not be safe. The most common side effects are stomach pain and nausea, reported in clinical studies.

More rarely, long-term use carries a risk of serious nerve and movement disorders — symptoms that can resemble Parkinson disease. Human safety data are limited, and lab studies raise concerns about possible nerve toxicity with long-term use.

Even people with existing Parkinson disease show worsened symptoms after consuming graviola. Because of these concerns, the safety data advise against use during pregnancy and breastfeeding — not enough is known about its effects on a developing baby or nursing infant.

Side effects, ingredient by ingredient Graviola

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Graviola.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take carbamazepine (Tegretol) or any other seizure medication — graviola may lower its blood levels and reduce how well it works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Graviola is not recommended for regular or long-term use given the potential for serious nerve-related side effects and limited safety data. If you take carbamazepine or have Parkinson disease, avoid this product.

Anyone considering it should talk with their doctor or pharmacist first, especially if they're pregnant, breastfeeding, or taking any medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Graviola 530 mg, straight from the product label.

Brand Swanson
Barcode (UPC) 087614117676
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 308593
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Graviola 530 mg by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
087614117676
IngredientAmount% DV
Graviola530 mg--

Other ingredients: Gelatin, Rice Bran, Rice extract Blend, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Promotes a feeling of calmness and relaxation Supports mood regulation Maintains immune health

Mental and emotional health

General Statements

Science-backed quality since 1969

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one capsule per day with water.

Precautions

Warning: For adults only. Keep out of reach of children.

Do not take this product if you are pregnant or nursing. Consult your healthcare provider before use if you are taking blood pressure medication or products that increase ATP levels (CoQ10).

If taking this product for longer than 30 days, supplementing with probiotics and digestive enzymes is recommended. Long-term use and/or excessive use can lead to changes in neurological function. Discontinue use immediately if you experience any changes in neurological function. Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Graviola 530 mg per capsule

FDA Statement of Identity

Herbal Supplement

See for yourself

Graviola 530 mg by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Graviola 530 mg by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Graviola

Interacts with
1 drug
530 mg per serving

Graviola (soursop) is a tropical fruit tree whose leaves, fruit, and bark are used in traditional medicine, especially in parts of South America, Afri...

Graviola monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Bran, Rice extract Blend, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Graviola 530 mg by Swanson Drug Interactions

Want to check YOUR meds against Graviola 530 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Graviola 530 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Graviola1 drug type · 1 drug

Carbamazepine (Tegretol)

Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
A study in rats shows that graviola extract reduces the area under the curve of carbamazepine by 46% and maximum concentration by 35% when compared with carbamazepine alone.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Graviola 530 mg, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Graviola 530 mg by Swanson: Common Questions

Does Graviola 530 mg by Swanson interact with any medications?
Yes. Based on its ingredients, Graviola 530 mg has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Graviola 530 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
No. The safety data advise against graviola use during pregnancy and breastfeeding because not enough is known about how it affects a developing baby or nursing infant. Talk with your doctor or pharmacist before taking this product if you are pregnant, planning to become pregnant, or breastfeeding.
What side effects should I watch for?
The most common are stomach pain and nausea. Rarely, long-term use may cause serious nerve and movement disorders that resemble Parkinson disease. If you have Parkinson disease or a family history of it, avoid this product — even small amounts are linked to worsening symptoms.
Does graviola actually work for HPV, headaches, or other conditions?
The evidence isn't there yet. Graviola has been studied for human papillomavirus infection, headache, insect repellent use, and male infertility, but all have insufficient reliable evidence to rate its effectiveness. Ask your doctor about proven treatments for whatever you're dealing with.
Is graviola safe to take long-term?
Regular consumption may not be safe. Lab studies raise concerns about possible nerve toxicity with long-term use, and the serious side effects documented are concerning enough that long-term use isn't recommended without strong medical reason and close monitoring.
What is graviola and where does it come from?
Graviola, also called soursop, is a tropical fruit. This product is a capsule extract at 530 mg per dose, combined with rice bran, rice extract, gelatin, and silica.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Graviola 530 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Graviola 530 mg label
Go deeper

The Full Monographs Behind Graviola 530 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Graviola 530 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Graviola 4 references
  1. Caparros-Lefebvre D, Elbaz A. Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: a case-control study. Caribbean Parkinsonism Study Group. Lancet 1999;354:281-6. PubMed
  2. Gavamukulya Y, Wamunyokoli F, El-Shemy HA. Annona muricata: Is the natural therapy to most disease conditions including cancer growing in our backyard? A systematic review of its research history and future prospects. Asian Pac J Trop Med. 2017;10(9):835- PubMed
  3. Abu Soukhon AA, Abu-Qatouseh L, Mansoor K, et al. Cytotoxicity Activity of Graviola Fruit Extract with Carbamazepine and Valproic Acid Show Antagonistic and Indifferent Effects. Asian Pac J Cancer Prev 2023;24(6):1869-1875. PubMed
  4. Cleret de Langavant L, Roze E, Petit A, et al. Annonaceae Consumption Worsens Disease Severity and Cognitive Deficits in Degenerative Parkinsonism. Mov Disord 2022;37(12):2355-2366. PubMed

See these in context on the Graviola monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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