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Dietary supplement

Graviola750 Ingredients & Drug Interactions

by Maximum

Graviola750 label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Graviola750 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Graviola750 is a dietary supplement by Maximum with 1 active ingredient. Its ingredients are commonly taken for cancer support (unproven), infections, inflammation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Graviola. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Graviola750 by Maximum

Ask about any prescription or over-the-counter medication and we check it for interactions with Graviola750 by Maximum — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Graviola750 by Maximum

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Maximum Graviola750 contains one active ingredient: graviola (from the graviola tree). The capsule also includes inactive ingredients—hypromellose, dicalcium phosphate, silicon dioxide, and magnesium stearate—which are fillers and binders that help form and hold the capsule together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Graviola product and its label doesn't state a use — see Graviola's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for graviola is limited. Our data shows insufficient reliable evidence to rate it for human papillomavirus (HPV), headache, male infertility, or use as an insect repellent.

In other words, we don't have solid proof that it works for any of these purposes, and more rigorous studies would be needed to know.

The evidence, ingredient by ingredient Graviola

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Regular use of graviola raises safety concerns. The most common side effects from oral use are stomach pain (epigastrium pain) and nausea, though these tend to be mild.

More rarely, graviola has been linked to movement disorders and nerve damage (myeloneuropathy) that resemble Parkinson disease symptoms. One study found that even low amounts of graviola fruit, juice, or herbal tea may worsen motor and thinking symptoms in people with Parkinson disease.

Graviola is rated possibly unsafe in pregnancy and should be avoided while breastfeeding due to insufficient safety data. Because human safety information is limited and lab studies raise concerns about possible nerve toxicity with long-term use, talk with your doctor or pharmacist before taking this product, especially if you plan to use it regularly.

Side effects, ingredient by ingredient Graviola

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Graviola.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take carbamazepine (Tegretol) or any other anti-seizure medication, check with your doctor or pharmacist before starting Graviola750. Graviola may lower carbamazepine levels enough to reduce how well it controls seizures.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Graviola has very limited evidence for any health use, and regular consumption carries real safety concerns—particularly the risk of nerve damage and movement problems over time. If you take carbamazepine (Tegretol) for seizures, you must check with your doctor or pharmacist before using this product, as it may reduce the drug's effectiveness.

If you're pregnant or breastfeeding, it's best avoided. Talk it over with your own healthcare provider to decide if this is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Graviola750, straight from the product label.

Brand Maximum
Barcode (UPC) 800326500051
Net contents 100 Veggie Cap(s)
Market status On market
Date entered into DSLD Jul 24, 2019
DSLD ID 204994
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Graviola750 by Maximum, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
50
UPC/BARCODE
800326500051
IngredientAmount% DV
Graviola750 mg--

Other ingredients: Hypromellose, Dicalcium Phosphate, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Manufactured in a GMP facility

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Made in the USA

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Take two (2) capsules 3 to 4 times per day.

Precautions

Keep out of reach of children!

Do not use if safety seal is broken or missing.

Warning: Consult a physician before using this or any product, if you are pregnant, lactating or have a medical condition.

Storage

Store product in a cool and dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Graviola750 by Maximum label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Graviola750 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Graviola750 by Maximum

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Graviola

Interacts with
1 drug
750 mg per serving

Graviola (soursop) is a tropical fruit tree whose leaves, fruit, and bark are used in traditional medicine, especially in parts of South America, Afri...

Graviola monograph & interactions

Other (inactive) ingredients: Hypromellose, Dicalcium Phosphate, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Graviola750 by Maximum Drug Interactions

Want to check YOUR meds against Graviola750?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Graviola 1

Individual Drug Interactions

The ingredients in Graviola750 interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in Graviola750 interact with drugs. Each result below shows which ingredient is responsible. Graviola

Each ingredient & the kinds of drugs it affects

For each ingredient in Graviola750 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Graviola1 drug type · 1 drug

Carbamazepine (Tegretol)

Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
A study in rats shows that graviola extract reduces the area under the curve of carbamazepine by 46% and maximum concentration by 35% when compared with carbamazepine alone.

Likelihood Possible Evidence D
Graviola full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Graviola750, from the product label.

Maximum

See all Maximum products
Name
Maximum International
Street Address
500 Northeast 25th Street
City
Pompano Beach
State
FL
ZipCode
33064
Phone Number
1(800) 940-2030
Web Address
www.MaximumInternational.com
Pharmacist Counseling Corner

Graviola750 by Maximum: Common Questions

Does Graviola750 by Maximum interact with any medications?
Yes. Based on its ingredients, Graviola750 has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Graviola750 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is graviola safe to take long-term?
Regular consumption of graviola may be unsafe. Lab studies raise concerns about possible nerve toxicity with long-term use, and there's a rare but serious risk of movement disorders and nerve damage (myeloneuropathy) that can look like Parkinson disease. Because human safety data are limited, talk with your doctor or pharmacist before using it regularly.
What are the common side effects?
The most common side effects from taking graviola orally are stomach pain (epigastrium pain) and nausea. In a clinical study, some people reported these after taking graviola leaf extract daily.
Can I take this if I'm pregnant or breastfeeding?
No. Graviola is rated possibly unsafe in pregnancy and should be avoided while breastfeeding due to insufficient safety data. Talk with your doctor or pharmacist if you have questions about alternatives.
What is graviola supposed to help with?
In our data, graviola is listed for human papillomavirus (HPV), headache, male infertility, and insect repellent use, but there is insufficient reliable evidence to say it actually works for any of these.
Does this product contain any fillers?
Yes. Besides the active graviola, the capsule contains inactive ingredients: hypromellose, dicalcium phosphate, silicon dioxide, and magnesium stearate. These are standard excipients that help form the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Graviola750 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Graviola750 label
Go deeper

The Full Monographs Behind Graviola750’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Graviola

Interacts with 1 drug

Graviola (soursop) is a tropical fruit tree whose leaves, fruit, and bark are used in traditional medicine, especially in parts of South America, Africa, and Asia. Despite popular online cla...

Read the full Graviola monograph →
Sources

Sources & How We Checked

Graviola750's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Graviola 4 references
  1. Caparros-Lefebvre D, Elbaz A. Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: a case-control study. Caribbean Parkinsonism Study Group. Lancet 1999;354:281-6. PubMed
  2. Gavamukulya Y, Wamunyokoli F, El-Shemy HA. Annona muricata: Is the natural therapy to most disease conditions including cancer growing in our backyard? A systematic review of its research history and future prospects. Asian Pac J Trop Med. 2017;10(9):835- PubMed
  3. Abu Soukhon AA, Abu-Qatouseh L, Mansoor K, et al. Cytotoxicity Activity of Graviola Fruit Extract with Carbamazepine and Valproic Acid Show Antagonistic and Indifferent Effects. Asian Pac J Cancer Prev 2023;24(6):1869-1875. PubMed
  4. Cleret de Langavant L, Roze E, Petit A, et al. Annonaceae Consumption Worsens Disease Severity and Cognitive Deficits in Degenerative Parkinsonism. Mov Disord 2022;37(12):2355-2366. PubMed

See these in context on the Graviola monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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