No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Green Lipped Mussel Capsules 750 mg Ingredients & Drug Interactions

by BulkSupplements.com

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Green Lipped Mussel Capsules 750 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for osteoarthritis joint pain, rheumatoid arthritis symptoms, joint stiffness and mobility.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Green Lipped Mussel Capsules 750 mg by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: green-lipped mussel at 750 mg per capsule. The capsule itself is made from bovine gelatin, which is an inactive ingredient.

Green-lipped mussel (also called New Zealand green-lipped mussel) is a shellfish harvested off the coast of New Zealand. It's used in supplements for a range of purposes, though the evidence for most of those uses isn't yet established in our data.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient New Zealand Green-lipped Mussel product and its label doesn't state a use — see New Zealand Green-lipped Mussel's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for green-lipped mussel isn't established in the data we hold. The product's potential uses — asthma, ADHD, breast cancer, and exercise-induced muscle soreness — all show insufficient reliable evidence to rate right now.

That doesn't mean it won't work; it means larger or better-designed studies are needed to know for sure.

The evidence, ingredient by ingredient New Zealand Green-lipped Mussel

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Green-lipped mussel is generally well tolerated by mouth. The most common side effects are mild: abdominal pain, acid reflux, diarrhea, flatulence, and nausea.

In rare cases, liver inflammation (hepatitis) and abnormal liver function have been reported with certain mussel extracts, so if you have liver disease or concerns, mention this supplement to your doctor. If you have a shellfish allergy, avoid this product entirely.

During pregnancy, the safety data is limited — the product is rated possibly unsafe, so it's best avoided unless you've talked with your doctor. While breastfeeding, safety hasn't been established, so it's best to skip it.

Side effects, ingredient by ingredient New Zealand Green-lipped Mussel

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, run your exact medications through the checker on this page or ask your pharmacist before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Green-lipped mussel is generally well tolerated and has no documented drug interactions, but the evidence for what it actually does isn't clear yet. If you have a shellfish allergy, are pregnant, or are breastfeeding, don't take it.

Before you start, mention it to your pharmacist — especially if you have liver concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Green Lipped Mussel Capsules 750 mg, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X003XHJ17B
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 330013
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Green Lipped Mussel Capsules 750 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
X003XHJ17B
IngredientAmount% DV
Green-Lipped Mussel750 mg--

Other ingredients: Bovine Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Green Lipped Mussel Capsules 750 mg per serving

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 capsule daily, or as directed by a physician.

Precautions

Allergen statement: Contains shellfish

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Formulation

Free of: Added sugar, soy, dairy, yeast, gluten, additives

Storage

Store in a dry, cool place

General Statements

Scan me New

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Green Lipped Mussel Capsules 750 mg by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Green Lipped Mussel Capsules 750 mg by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Green-Lipped Mussel

No known
interactions
750 mg per serving Form: Protein

New Zealand green-lipped mussel is a shellfish-derived supplement rich in omega-3 fats that is mostly used for joint pain and arthritis. Some studies...

Green-Lipped Mussel monograph & interactions

Other (inactive) ingredients: Bovine Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Green Lipped Mussel Capsules 750 mg by BulkSupplements.com Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Green Lipped Mussel Capsules 750 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Green Lipped Mussel Capsules 750 mg, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Green Lipped Mussel Capsules 750 mg by BulkSupplements.com: Common Questions

Does Green Lipped Mussel Capsules 750 mg by BulkSupplements.com interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Green Lipped Mussel Capsules 750 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Green Lipped Mussel Capsules 750 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe if I have a shellfish allergy?
No. Green-lipped mussel is a shellfish, so you should avoid it if you have a shellfish allergy.
Can I take this while pregnant?
There isn't enough safety data to say it's safe during pregnancy — it's rated possibly unsafe. Talk with your doctor or pharmacist before taking it.
Can I take this while breastfeeding?
Safety hasn't been established for breastfeeding, so it's best to avoid it. Check with your doctor or pharmacist.
What are the most common side effects?
Mild digestive issues: abdominal pain, acid reflux, diarrhea, flatulence, and nausea. Serious side effects like liver inflammation are rare.
Does green-lipped mussel really work for arthritis or joint pain?
The evidence isn't established in our data yet. We do hold evidence ratings for asthma, ADHD, breast cancer, and exercise soreness — all show insufficient evidence to rate right now.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Green Lipped Mussel Capsules 750 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Green Lipped Mussel Capsules 750 mg label
Go deeper

The Full Monographs Behind Green Lipped Mussel Capsules 750 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Green Lipped Mussel Capsules 750 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

New Zealand Green-lipped Mussel 12 references
  1. Miller T, Wu H. In vivo evidence for prostaglandin inhibitory activity in New Zealand green-lipped mussel extract. N Z Med J 1984;97:355-7.
  2. Gibson SLM, Gibson RG. The treatment of arthritis with a lipid extract of Perna canaliculus: a randomised trial. Complement Ther Med 1998;6:122-6.
  3. Gibson RG, Gibson SL, Conway V, Chappell D. Perna canaliculus in the treatment of arthritis. Practitioner 1980;224:955-60.
  4. Fabrin, B. [Possible toxic hepatitis after intake of an alternative preparation]. Ugeskr.Laeger 6-13-1988;150(24):1474-1475.
  5. Gibson, R. G. and Gibson, S. L. Green-lipped mussel extract in arthritis. Lancet 2-21-1981;1(8217):439. PubMed
  6. Ahern, M. J., Milazzo, S. C., and Dymock, R. Granulomatous hepatitis and Seatone. Med J Aust 8-9-1980;2(3):151-152. PubMed
  7. Croft, J. E. Granulomatous hepatitis and Seatone. Med J Aust 10-4-1980;2(7):401-402. PubMed
  8. Lau, S., Chiu, P. K., Chu, E. M. Y., Cheng, I. Y. W., Tang, W. M., Man, R. Y. K., and Halpern, G. M. Treatment of knee osteoarthritis with Lyprinol, lipid extract of the green-lipped mussel - a double-blind placebo-controlled study. Progress in Nutrition
  9. Gruenwald, J., Graubaum, H., Hansen, K., and Grube, B. Efficacy and tolerability of a combination of LYPRINOL and high concentrations of EPA and DHA in inflammatory rheumatoid disorders... eicosapentaenoic acid... decosahexaenoid acid. Advances in Therap PubMed
  10. Coulson S, Vecchio P, Gramotnev H, Vitetta L. Green-lipped mussel (Perna canaliculus) extract efficacy in knee osteoarthritis and improvement in gastrointestinal dysfunction: a pilot study. Inflammopharmacology 2012;20:71-6. PubMed
  11. Sukumaran S, Pittman KB, Patterson WK, et al. A phase I study to determine the safety, tolerability and maximum tolerated dose of green-lipped mussel (Perna canaliculus) lipid extract, in patients with advanced prostate and breast cancer. Ann Oncol 2010;2 PubMed
  12. Lello J, Liang A, Robinson E, et al. Treatment of children's asthma with a lipid extract of the new Zealand green lipped mussel (Perna canaliculus) (Lyprinol®)-A double blind, randomized controlled trial in children with moderate to serve chronic obstruct

See these in context on the New Zealand Green-lipped Mussel monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring