Green Lipped Mussel Powder Ingredients & Drug Interactions
by XtendLife
What is this page for?
First and foremost: checking Green Lipped Mussel Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Green Lipped Mussel Powder is a dietary supplement by XtendLife with 1 active ingredient. Its ingredients are commonly taken for osteoarthritis joint pain, rheumatoid arthritis symptoms, joint stiffness and mobility.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Green Lipped Mussel Powder by XtendLife
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: green-lipped mussel powder, a nutrient-rich extract from New Zealand mussels. The capsule itself is an inactive ingredient (the container for the powder).
Does it work?
Not established
The evidence for green-lipped mussel is limited across several conditions we have data on — asthma, ADHD, breast cancer, and exercise-induced muscle soreness — we don't have enough reliable evidence to rate whether it works for any of them. If you're considering it for a specific health goal, talk with your pharmacist or doctor about what the research currently shows.
How safe is it?
Well-documented data
Green-lipped mussel is generally well tolerated by most people. Common side effects reported in studies include abdominal pain, acid reflux, diarrhea, flatulence, and nausea — most people don't experience these, but they're worth knowing about.
Rare cases of liver inflammation (hepatitis) and liver function abnormalities have been reported, particularly with a specific mussel extract called Seatone. If you have a shellfish allergy, avoid this product — it comes from mussels and could trigger an allergic reaction.
Pregnancy and breastfeeding are both cautionary: there isn't enough safety data to use it during pregnancy (rated possibly unsafe), and safety hasn't been established for breastfeeding, so the data advises against it.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we checked.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
Green-lipped mussel powder is well tolerated by most people and has no documented drug interactions. It's not the right choice if you're pregnant, breastfeeding, or allergic to shellfish.
Talk with your pharmacist before starting it, especially to discuss whether it fits your health goal — the evidence is still thin for most uses.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Green Lipped Mussel Powder, straight from the product label.
| Brand | XtendLife |
|---|---|
| Net contents | 120 Capsule(s); 600 mg |
| Market status | Off market |
| Date entered into DSLD | Apr 25, 2014 |
| DSLD ID | 32025 |
| Product type | Amino Acid/protein |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Green Lipped Mussel Powder by XtendLife, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 {Calories} | -- |
| Green Lipped Mussel Powder | 2400 mg | -- |
Other ingredients: Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions For Use Take 4 capsules per day, anytime, with or after food.
Brand IP Statement(s)
Xtend-Life(TM) Green Lipped Mussel Powder aims to help support healthy joint function, and provide nutritional support for skin and connective tissues.
Storage
Store in a cool, dry place.
General Statements
Batch number: Manufactured: Use by date:
love life. live life.
From the Pristine Waters of Marlborough, New Zealand
100% Pure and Natural
Made in New Zealand
Xtend-Life's Green Lipped Mussel powder is a 100% natural product from selected mussels cultured in the pristine waters of Marlborough, New Zealand. These mussels are processed using a proprietary method that enables ALL the components of the mussel to remain intact. Fresh live mussels are converted to the finished powder in a little over 30 minutes. This ensures unequalled freshness, and because this process does not require cooking, all of the valuable fractions of the mussels are preserved.
A typical analysis of Xtend-Life's Green Lipped Mussel Powder. 45% proteins and essential amino acids 30% mucopolysaccharides, chondroitins and marine collagens 12% natural vitamins (A, B complex, D, E), minerals and trace elements 10% marine lipids (including omega-3 fatty acids)
Not a significant source of Vitamin A, Calcium or Iron
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
L1043-6
Formulation
No additives
Does not contain dairy, gluten or peanut Does not contain any additives
Seals/Symbols
BEST QUALITY GUARANTEE
FDA Statement of Identity
Dietary Supplement
Formula
Contains shellfish material
Precautions
Contains shellfish material
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Green Lipped Mussel Powder by XtendLife label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Green Lipped Mussel Powder by XtendLife
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size4 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Green Lipped Mussel Powder
No knowninteractions
New Zealand green-lipped mussel is a shellfish-derived supplement rich in omega-3 fats that is mostly used for joint pain and arthritis. Some studies...
Green Lipped Mussel Powder monograph & interactionsOther (inactive) ingredients: Capsule. These complete the product’s ingredient list but are not active constituents.
Green Lipped Mussel Powder by XtendLife Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Green Lipped Mussel Powder. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Green Lipped Mussel Powder, from the product label.
XtendLife
- Web Address
- www.xtend-life.com
Green Lipped Mussel Powder by XtendLife: Common Questions
Does Green Lipped Mussel Powder by XtendLife interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this interact with my blood pressure or cholesterol medication?
Is it safe if I have a shellfish allergy?
Can I take this while pregnant or breastfeeding?
What are the side effects?
Does it actually work for joint pain or inflammation?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Green Lipped Mussel Powder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Green Lipped Mussel Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Green Lipped Mussel Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
New Zealand Green-lipped Mussel 12 references
- Miller T, Wu H. In vivo evidence for prostaglandin inhibitory activity in New Zealand green-lipped mussel extract. N Z Med J 1984;97:355-7.
- Gibson SLM, Gibson RG. The treatment of arthritis with a lipid extract of Perna canaliculus: a randomised trial. Complement Ther Med 1998;6:122-6.
- Gibson RG, Gibson SL, Conway V, Chappell D. Perna canaliculus in the treatment of arthritis. Practitioner 1980;224:955-60.
- Fabrin, B. [Possible toxic hepatitis after intake of an alternative preparation]. Ugeskr.Laeger 6-13-1988;150(24):1474-1475.
- Gibson, R. G. and Gibson, S. L. Green-lipped mussel extract in arthritis. Lancet 2-21-1981;1(8217):439. PubMed
- Ahern, M. J., Milazzo, S. C., and Dymock, R. Granulomatous hepatitis and Seatone. Med J Aust 8-9-1980;2(3):151-152. PubMed
- Croft, J. E. Granulomatous hepatitis and Seatone. Med J Aust 10-4-1980;2(7):401-402. PubMed
- Lau, S., Chiu, P. K., Chu, E. M. Y., Cheng, I. Y. W., Tang, W. M., Man, R. Y. K., and Halpern, G. M. Treatment of knee osteoarthritis with Lyprinol, lipid extract of the green-lipped mussel - a double-blind placebo-controlled study. Progress in Nutrition
- Gruenwald, J., Graubaum, H., Hansen, K., and Grube, B. Efficacy and tolerability of a combination of LYPRINOL and high concentrations of EPA and DHA in inflammatory rheumatoid disorders... eicosapentaenoic acid... decosahexaenoid acid. Advances in Therap PubMed
- Coulson S, Vecchio P, Gramotnev H, Vitetta L. Green-lipped mussel (Perna canaliculus) extract efficacy in knee osteoarthritis and improvement in gastrointestinal dysfunction: a pilot study. Inflammopharmacology 2012;20:71-6. PubMed
- Sukumaran S, Pittman KB, Patterson WK, et al. A phase I study to determine the safety, tolerability and maximum tolerated dose of green-lipped mussel (Perna canaliculus) lipid extract, in patients with advanced prostate and breast cancer. Ann Oncol 2010;2 PubMed
- Lello J, Liang A, Robinson E, et al. Treatment of children's asthma with a lipid extract of the new Zealand green lipped mussel (Perna canaliculus) (Lyprinol®)-A double blind, randomized controlled trial in children with moderate to serve chronic obstruct
See these in context on the New Zealand Green-lipped Mussel monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC