No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

GW 501516 Extreme Ingredients & Drug Interactions

by Mass Genetics

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

GW 501516 Extreme is a dietary supplement by Mass Genetics with 1 active ingredient. Its ingredients are commonly taken for endurance and athletic performance, fat loss and body recomposition, bodybuilding cycles.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of GW 501516 Extreme by Mass Genetics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: cardarine, a research compound being investigated for potential effects on athletic performance, blood sugar, and weight. The capsule also contains microcrystalline cellulose, magnesium stearate, and silicon dioxide as inactive ingredients (binders and flow agents).

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: fat loss and endurance for athletic performance.
  • We looked for evidence on: Athletic performance, Obesity, body composition, exercise capacity.
  • The closest evidence on file: Cardarine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Cardarine is rated "Insufficient Reliable Evidence To Rate" for Obesity.

The evidence we hold does not establish whether cardarine is effective for athletic performance, diabetes, or obesity—all three uses are rated as having insufficient reliable evidence to rate. This is in part because cardarine is not an approved medication and has not undergone the human trials needed to prove it works.

The evidence, ingredient by ingredient Cardarine

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cardarine is not approved for human use, and animal studies linked it to cancer. The safety data advises against use during pregnancy and while breastfeeding due to unknown safety in humans and serious toxicity concerns.

Because cardarine has not been adequately tested in people, adverse effects in humans are not well characterized. Talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Cardarine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredient we could check. However, because cardarine is not an approved human drug and has not been thoroughly studied, unknown interactions with medications are possible.

Discuss this product with your doctor or pharmacist before combining it with any medications you take.

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.

Cardarine is a research chemical without FDA approval and without proof it is safe or effective in humans. Animal studies raised cancer concerns.

If you're considering it for athletic performance, blood sugar control, or weight management, talk it over with your doctor or pharmacist first—they can discuss whether it's right for you and what risks it may carry.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about GW 501516 Extreme, straight from the product label.

Brand Mass Genetics
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Dec 22, 2019
DSLD ID 211527
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for GW 501516 Extreme by Mass Genetics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
IngredientAmount% DV
Cardarine10 mg--

Other ingredients: Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Fat metabolizer & extreme endurance Anti catabolic Lean muscle

Contains no sugar, salt, starch, yeast, milk, egg, shellfish, preservatives, artificial flavors and colors.

FDA Statement of Identity

Sports Supplement

General Statements

PPAR Product

See for yourself

GW 501516 Extreme by Mass Genetics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in GW 501516 Extreme by Mass Genetics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Cardarine

No known
interactions
10 mg per serving

Cardarine (GW501516) is a synthetic experimental drug, not a vitamin, herb, or true dietary supplement, even though it is often sold as one. Animal st...

Cardarine monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

GW 501516 Extreme by Mass Genetics Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in GW 501516 Extreme. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for GW 501516 Extreme, from the product label.

Mass Genetics

See all Mass Genetics products
Name
Mass Genetics
Pharmacist Counseling Corner

GW 501516 Extreme by Mass Genetics: Common Questions

Does GW 501516 Extreme by Mass Genetics interact with any medications?
We do not currently list a known interaction for the mapped ingredients in GW 501516 Extreme. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
GW 501516 Extreme contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is cardarine safe to use?
Cardarine is not FDA approved and is not proven safe for human use. Animal studies linked it to cancer, and it has not been adequately tested in people. The safety data advises against use, and you should discuss any interest in taking it with your doctor or pharmacist.
Can I take this while pregnant or breastfeeding?
No. The safety data advises against cardarine during pregnancy and while breastfeeding due to unknown safety and serious toxicity concerns in humans. Talk with your doctor if you have questions about what's safe during these times.
Does cardarine actually improve athletic performance?
The evidence we hold does not establish that it does. Athletic performance, diabetes, and obesity are all rated as having insufficient reliable evidence to rate—meaning human studies have not shown it works for these uses.
Will this interact with my medications?
No interactions are documented in our data for cardarine. However, because this is not an approved human drug and has not been thoroughly studied, unknown interactions are possible. Check your exact medications with your doctor or pharmacist before taking this product.
What are the inactive ingredients?
The capsule contains microcrystalline cellulose, magnesium stearate, and silicon dioxide—these are binders and flow agents that help form the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if GW 501516 Extreme is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

GW 501516 Extreme label
Go deeper

The Full Monographs Behind GW 501516 Extreme’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

GW 501516 Extreme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cardarine 1 reference
  1. What Should Tested Athletes Know About GW1516? Education, Spirit of Sport. U.S. Anti-Doping Agency (USADA). September 24, 2019. Available at: https://www.usada.org/spirit-of-sport/education/what-should-athletes-know-gw1516/

See these in context on the Cardarine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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