No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Hamamelis Vir. Witch Hazel Ingredients & Drug Interactions

by Wise Woman Herbals

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Hamamelis Vir. Witch Hazel is a dietary supplement by Wise Woman Herbals with 1 active ingredient. Its ingredients are commonly taken for skin irritation and inflammation, hemorrhoids, minor cuts and bruises.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Hamamelis Vir. Witch Hazel by Wise Woman Herbals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (3 mL) without saying how much of each component you get.

This product contains one active ingredient: witch hazel, a plant extract traditionally used for skin concerns. The liquid form also includes spring water, alcohol, and glycerine as inactive ingredients that help deliver and preserve the witch hazel.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: skin health and minor wound care.
  • We looked for evidence on: Acne, Atopic dermatitis (eczema), Bruises, Burns, Hemorrhoids, Insect bite — and 4 related terms.
  • The strongest evidence on file: Witch Hazel is rated "Possibly Effective" for Hemorrhoids (Natural Medicines).
  • Also on file: Witch Hazel is rated "Possibly Ineffective" for Atopic dermatitis (eczema).
  • Also on file: Witch Hazel is rated "Insufficient Reliable Evidence To Rate" for Acne, Burns, Minor bleeding, Skin irritation, and more.

Witch hazel is possibly effective for hemorrhoids. For eczema (atopic dermatitis), the evidence suggests it's possibly ineffective.

For varicose veins and postmenopausal symptoms, we don't have enough reliable evidence to rate how well it works.

The evidence, ingredient by ingredient Witch Hazel

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Topically, witch hazel is generally well tolerated short-term. The most common side effect when applied to skin is contact dermatitis — a small number of people develop redness or burning.

This product is meant for topical use only and should not be taken by mouth. Witch hazel contains tannins, compounds that in very high oral doses may pose risks to the kidneys and liver, though topical use is considered likely low risk.

Because safety data are limited, especially during pregnancy and breastfeeding, check with your doctor before use.

Side effects, ingredient by ingredient Witch Hazel

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, use the medication checker below or ask your pharmacist to verify your specific drugs before you start.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you're looking to try witch hazel for hemorrhoid relief, this topical form is generally well tolerated with minimal side effects for most people. It's not the right choice if you're thinking of taking it by mouth.

Talk to your pharmacist if you have sensitive skin or a history of contact dermatitis, or if you're pregnant, breastfeeding, or planning either.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hamamelis Vir. Witch Hazel, straight from the product label.

Brand Wise Woman Herbals
Barcode (UPC) 748840010079
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD May 24, 2023
DSLD ID 284845
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hamamelis Vir. Witch Hazel by Wise Woman Herbals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10 Drop(s)
Maximum serving Sizes:
60 Drop(s)
Servings per container
20
UPC/BARCODE
748840010079
IngredientAmount% DV
Proprietary Blend3 mL--
Witch Hazel0 NP--

Other ingredients: spring Water, Alcohol, Glycerine

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Shake well. Add 10-60 drops to water, 1-4 times per day.

General Statements

The presence of particulate matter in this product is normal.

Botanical formula

Precautions

Caution: Keep out of the reach of children.

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry area away from direct sunlight with the lid tightly sealed.

See for yourself

Hamamelis Vir. Witch Hazel by Wise Woman Herbals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Hamamelis Vir. Witch Hazel by Wise Woman Herbals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size10 Drop(s) Dosage formLiquid Servings per container20 Amounts shown are per serving.

Proprietary Blend

3 mL per serving

Other (inactive) ingredients: Spring Water, Alcohol, Glycerine. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hamamelis Vir. Witch Hazel by Wise Woman Herbals Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Hamamelis Vir. Witch Hazel. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Hamamelis Vir. Witch Hazel, from the product label.

Wise Woman Herbals

See all Wise Woman Herbals products
Name
Wise Woman Herbals
City
Creswell
State
OR
ZipCode
97426
Phone Number
541.895.5152
Web Address
wisewomanherbals.com
Pharmacist Counseling Corner

Hamamelis Vir. Witch Hazel by Wise Woman Herbals: Common Questions

Does Hamamelis Vir. Witch Hazel by Wise Woman Herbals interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Hamamelis Vir. Witch Hazel. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Hamamelis Vir. Witch Hazel contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is witch hazel safe to use while pregnant or breastfeeding?
The safety data we hold for witch hazel during pregnancy and breastfeeding aren't complete enough to say yes or no. Because it's intended for topical use and not meant to be swallowed, the risk is likely low — but there's not enough evidence to be certain. Talk with your doctor or pharmacist for personalized advice.
Can I take witch hazel by mouth?
No. This product is meant for topical (skin) use only. Witch hazel should not be swallowed, especially in high doses, because the tannins it contains could harm your kidneys and liver.
What side effects might I notice?
When applied to skin, witch hazel is generally well tolerated. A small number of people develop contact dermatitis — redness or burning where they applied it. If that happens, stop use and rinse with water.
Will this help my eczema?
The evidence suggests witch hazel is possibly ineffective for eczema. If you're looking to treat atopic dermatitis, ask your pharmacist or doctor about other options that have stronger evidence behind them.
What are the inactive ingredients?
This liquid contains spring water, alcohol, and glycerine. These help preserve the witch hazel and keep it in liquid form.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hamamelis Vir. Witch Hazel is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hamamelis Vir. Witch Hazel label
Go deeper

The Full Monographs Behind Hamamelis Vir. Witch Hazel’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Hamamelis Vir. Witch Hazel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Witch Hazel 7 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  4. Hormann HP, Korting HC. Evidence for the efficacy and safety of topical herbal drugs in dermatology: part I: anti-inflammatory agents. Phytomedicine 1994;1:161-71. PubMed
  5. Wolff, H. H. and Kieser, M. Hamamelis in children with skin disorders and skin injuries: results of an observational study. Eur.J.Pediatr. 2007;166(9):943-948. PubMed
  6. Khanna, N. and Datta, Gupta S. Rejuvenating facial massage--a bane or boon? Int J Dermatol. 2002;41(7):407-410. PubMed
  7. Theisen LL, Erdelmeier CA, Spoden GA, Boukhallouk F, Sausy A, Florin L, Muller CP. Tannins from Hamamelis virginiana bark extract: characterization and improvement of the antiviral efficacy against influenza A virus and human papillomavirus. PLoS One. 201 PubMed

See these in context on the Witch Hazel monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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